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Sökning: WFRF:(Agren H) > (2020-2024)

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1.
  • Zhao, Y., et al. (författare)
  • Bismuth nanoplatelets : universal synthetic strategy and emerging application for PEC-type photodetectors
  • 2023
  • Ingår i: MATERIALS TODAY NANO. - : Elsevier BV. - 2588-8420. ; 23
  • Tidskriftsartikel (refereegranskat)abstract
    • Bi nanoplatelets (NPLs) with a narrow size distribution and high yield have been successfully fabricated by a novel two-step sonication-assisted solvothermal method. Applied as photo-electrochemical (PEC)-type photodetectors (PDs), it is shown that the Bi NPLs exhibit a pronounced photo-response ranging from the ultraviolet to the visible regions. The photo-response performance of Bi NPLs-based PDs was adjusted by external conditions and interpreted by density functional theory calculations in terms of the formation of the respective Bi-based compounds. The PEC results demonstrate that the optimal photocurrent density (P-ph) and photoresponsivity (R-ph) can reach 12.27 mu A/cm(2) and 3016 mu A/W in alkaline electrolytes, respectively. Besides, the Bi NPLs-based PDs exhibit superb long-term cycling stability (similar to 97.86% remained after 1000 cycles). We conclude that Bi NPLs demonstrate great promise as an emerging building block for the design of high-performance PEC-type PDs as well as other novel optoelectronic devices, holding the potential for breakthrough developments in these fields.
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  • Fast, L, et al. (författare)
  • Fluorescence-Based Measurements of Membrane-Bound Angiotensin Converting Enzyme 2 Activity Using Xenopus Laevis Oocytes
  • 2022
  • Ingår i: Biosensors. - : MDPI AG. - 2079-6374. ; 12:8
  • Tidskriftsartikel (refereegranskat)abstract
    • Functional investigations of enzymes involving cellular expression systems are important for pharmacological studies. The precise control of expression is challenging in transiently transfected mammalian cell lines. Here, we explored the ability of Xenopus laevis oocytes to express a membrane-bound enzyme for functional characterization using standard 96-well plates and a fluorescence-based plate reader assay. We microinjected oocytes with cRNA encoding the angiotensin converting enzyme 2 (ACE2) and measured the enzymatic activity in single oocytes using a commercial fluorescence-based assay. The injected oocytes showed up to a 50-fold increase in fluorescence compared to uninjected oocytes. This fluorescence intensity was dose-dependent on the amount of ACE2 cRNA. These results suggest that Xenopus oocytes can be used for the functional evaluation of membrane-bound enzymes, decreasing the experimental workload.
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