| 1. |
- Alarcón, Alvaro, 1991-
(författare)
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All-Fiber System for Photonic States Carrying Orbital Angular Momentum : A Platform for Classical and Quantum Information Processing
- 2023
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The protection of confidential data is a fundamental need in the society in which we live. This task becomes more relevant when observing that every day, data traffic increases exponentially, as well as the number of attacks on the telecommunication infra-structure. From the natural sciences, it has been strongly argued that quantum communication has great potential to solve this problem, to such an extent that various governmental and industrial entities believe the protection provided by quantum communications will be an important layer in the field of information security in the next decades. However, integrating quantum technologies both in current optical networks and in industrial systems is not a trivial task, taking into account that a large part of current quantum optical systems are based on bulk optical devices, which could become an important limitation. Throughout this thesis we present an all-in-fiber optical platform that allows a wide range of tasks that aim to take a step forward in terms of generation and detection of photonic states. Among the main features, the generation and detection of photonic quantum states carrying orbital angular momentum stand out. The platform can also be configured for the generation of random numbers from quantum mechanical measurements, a central aspect in future information tasks. Our scheme is based on the use of new space-division-multiplexing (SDM) technologies such as few-mode-fibers and photonic lanterns. Furthermore, our platform can also be scaled to high dimensions, it operates in 1550 nm (telecommunications band) and all the components used for its implementation are commercially available. The results presented in this thesis can be a solid alternative to guarantee the compatibility of new SDM technologies in emerging experiments on optical networks and open up new possibilities for quantum communication.
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| 2. |
- Alarcon, Alvaro, et al.
(författare)
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All-in-Fiber Dynamically Reconfigurable Orbital Angular Momentum Mode Sorting
- 2023
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Ingår i: ACS Photonics. - : AMER CHEMICAL SOC. - 2330-4022. ; 10:10, s. 3700-3707
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Tidskriftsartikel (refereegranskat)abstract
- The orbital angular momentum (OAM) spatial degree of freedom of light has been widely explored in many applications, including telecommunications, quantum information, and light-based micromanipulation. The ability to separate and distinguish between the different transverse spatial modes is called mode sorting or mode demultiplexing, and it is essential to recover the encoded information in such applications. An ideal d mode sorter should be able to faithfully distinguish between the different d spatial modes, with minimal losses, and have d outputs and fast response times. All previous mode sorters rely on bulk optical elements, such as spatial light modulators, which cannot be quickly tuned and have additional losses if they are to be integrated with optical fiber systems. Here, we propose and experimentally demonstrate, to the best of our knowledge, the first all-in-fiber method for OAM mode sorting with ultrafast dynamic reconfigurability. Our scheme first decomposes the OAM mode in-fiber-optical linearly polarized (LP) modes and then interferometrically recombines them to determine the topological charge, thus correctly sorting the OAM mode. In addition, our setup can also be used to perform ultrafast routing of the OAM modes. These results show a novel and fiber-integrated form of optical spatial mode sorting that can be readily used for many new applications in classical and quantum information processing.
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| 3. |
- Alarcon, Alvaro, et al.
(författare)
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Dynamic generation of photonic spatial quantum states with an all-fiber platform
- 2023
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Ingår i: Optics Express. - : Optica Publishing Group. - 1094-4087. ; 31:6, s. 10673-10683
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Tidskriftsartikel (refereegranskat)abstract
- Photonic spatial quantum states are a subject of great interest for applications in quantum communication. One important challenge has been how to dynamically generate these states using only fiber-optical components. Here we propose and experimentally demonstrate an all-fiber system that can dynamically switch between any general transverse spatial qubit state based on linearly polarized modes. Our platform is based on a fast optical switch based on a Sagnac interferometer combined with a photonic lantern and few-mode optical fibers. We show switching times between spatial modes on the order of 5 ns and demonstrate the applicability of our scheme for quantum technologies by demonstrating a measurement-device-independent (MDI) quantum random number generator based on our platform. We run the generator continuously over 15 hours, acquiring over 13.46 Gbits of random numbers, of which we ensure that at least 60.52% are private, following the MDI protocol. Our results show the use of photonic lanterns to dynamically create spatial modes using only fiber components, which due to their robustness and integration capabilities, have important consequences for photonic classical and quantum information processing.(c) 2023 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement
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| 4. |
- Argillander, Joakim, et al.
(författare)
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Quantum random number generation based on a perovskite light emitting diode
- 2023
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Ingår i: Communications Physics. - : NATURE PORTFOLIO. - 2399-3650. ; 6:1
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Tidskriftsartikel (refereegranskat)abstract
- True random number generation is not thought to be possible using a classical approach but by instead exploiting quantum mechanics genuine randomness can be achieved. Here, the authors demonstrate a certified quantum random number generation using a metal-halide perovskite light emitting diode as a source of weak coherent polarisation states randomly producing an output of either 0 or 1. The recent development of perovskite light emitting diodes (PeLEDs) has the potential to revolutionize the fields of optical communication and lighting devices, due to their simplicity of fabrication and outstanding optical properties. Here we demonstrate that PeLEDs can also be used in the field of quantum technologies by implementing a highly-secure quantum random number generator (QRNG). Modern QRNGs that certify their privacy are posed to replace classical random number generators in applications such as encryption and gambling, and therefore need to be cheap, fast and with integration capabilities. Using a compact metal-halide PeLED source, we generate random numbers, which are certified to be secure against an eavesdropper, following the quantum measurement-device-independent scenario. The obtained generation rate of more than 10 Mbit s(-1), which is already comparable to commercial devices, shows that PeLEDs can work as high-quality light sources for quantum information tasks, thus opening up future applications in quantum technologies.
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| 5. |
- Nepomuceno, Thales C., et al.
(författare)
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BRCA1 frameshift variants leading to extended incorrect protein C termini
- 2023
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Ingår i: Human Genetics and Genomics Advances. - : Elsevier. - 2666-2477. ; 4:4
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Tidskriftsartikel (refereegranskat)abstract
- Carriers of BRCA1 germline pathogenic variants are at substantially higher risk of developing breast and ovarian cancer than the general population. Accurate identification of at-risk individuals is crucial for risk stratification and the implementation of targeted preventive and therapeutic interventions. Despite significant progress in variant classification efforts, a sizable portion of reported BRCA1 variants remain as variants of uncertain clinical significance (VUSs). Variants leading to premature protein termination and loss of essential functional domains are typically classified as pathogenic. However, the impact of frameshift variants that result in an extended incorrect terminus is not clear. Using validated functional assays, we conducted a systematic functional assessment of 17 previously reported BRCA1 extended incorrect terminus variants (EITs) and concluded that 16 constitute loss-of-function variants. This suggests that most EITs are likely to be pathogenic. However, one variant, c.5578dup, displayed a protein expression level, affinity to known binding partners, and activity in transcription and homologous recombination assays comparable to the wild-type BRCA1 protein. Twenty-three additional carriers of c.5578dup were identified at a US clinical diagnostic lab and assessed using a family history likelihood model providing, in combination with the functional data, a likely benign interpretation. These results, consistent with family history data in the current study and available data from ClinVar, indicate that most, but not all, BRCA1 variants leading to an extended incorrect terminus constitute loss-of-function variants and underscore the need for comprehensive assessment of individual variants.
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