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Träfflista för sökning "WFRF:(Alexopoulos P) ;srt2:(2020-2022)"

Sökning: WFRF:(Alexopoulos P) > (2020-2022)

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1.
  • Gao, Y., et al. (författare)
  • Characteristics of pre-ELM structures during ELM control experiment on JET with n=2 magnetic perturbations
  • 2016
  • Ingår i: Nuclear Fusion. - : IOP PUBLISHING LTD. - 0029-5515 .- 1741-4326. ; 56:9
  • Tidskriftsartikel (refereegranskat)abstract
    • Radially propagating pre-ELM (edge localized mode) structures in the heat flux profile on the outer divertor have been observed both with and without magnetic perturbations on Joint European Torus. Recently pre-ELM structures over 80% of the ELM cycle are observed. The effects of n = 2 fields on pre-ELM structures are presented and analysed in detail. Redistribution of the inter-ELM heat load with the appearances of pre-ELM structures suggest that a wider energy wetted area could be achieved by the application of n = 2 fields. The influences of q(95) and gas puffing position on the change of pre-ELM structures are studied. Pre-ELM structures are normally long lived (several milliseconds) and appear consecutively with n = 2 fields, but do not necessarily lead to an ELM crash. The experimental observations suggest that the changed magnetic topology might be a possible explanation for the propagating structures.
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  • Nelldal, Bo-Lennart, 1946-, et al. (författare)
  • VEL-Wagon: Implementation and migration strategy : Versatile, Efficient and Longer Wagon for European TransportationEC Grant agreement no: 265610 Deliverable 5.2
  • 2012
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • AbstractIn this report VEL-wagon has been analysed from the economic point of view, both as a part of an inter-modal train and as a part of an inter-modal transport chain. Also in D3.1 “Study on railway business for VEL-Wagon and target costs” economic calculations has been presented. In this report further analysis has been done with KTH and University of Žilina cost-models and some final conclusions will be presented. Also the wagon cost model has been further developed.In the wagon cost model the cost and mass breakdown of the VEL Wagon in its basic version (80 ft, 22.5 tonnes/axle) as well as potential versions (90 ft, 22.5 or 25 tonnes/axle).  To compare their relative efficiencies, the cost and mass model is also applied to modern, existing container wagons of 2-, 4-, and 6-axle configuration.The economic analysis of VEL-wagon shows that VEL-wagon in most cases is more efficient than other existing wagons when operating trains between the inter-modal terminals. The fact the wagon can transport 4 TEU on 2 bogies makes it more efficient than a 6-axle 80 ft wagon. But even more important is the flexibility to mix unit loads of different length on one wagon i.e. 20 ft and 40 ft containers. This makes it much more efficient than a 4-axle 60 ft wagon. It is also possible to load swap-bodies of 7.15-7.82 m length much more flexible than on existing wagons. The only case when VEL-wagon is not the best is transports of very heavy loaded unit loads, but this is not a common case. Cost for operating VEL-wagon has been calculated for Sweden, Germany and Slovakia. And in all these countries VEL-wagon is more efficient than other existing wagons on the market. The VEL-wagon has also been evaluated in a total inter-modal transport chain including terminal handling and feeder transports of the loading units. The distance for break-even-point to direct road transport has been calculated. That is important because there is a rank size rule that means the shorter distances the bigger volumes are available on the market. The VEL-wagon itself loaded with 4 TEU may shorten the break-even point with approximately 50 km for a typical inter-modal transport chain in Sweden compared with a 25,25m truck loading 3 TEU. In Sweden there are experiments with a 32m long truck which can load 4 TEU or haul two trailers. This will push break-even-point to 100 km longer distances. In Europe there are discussions to make the trucks longer than the ordinary 18 m. If Megatrucks with 25,25 will be introduced the break-even point will be pushed to 150 km longer distances. But the result of this depends not only of the weight but also of the weight.In long term there is a risk if 45 ft container will grow and axle load of 25 tonnes will be implemented in a wider network. A wagon with higher axle load seems to be easier to construct and build than a longer wagon because of the geometrical infrastructure parameters.VEL-wagon means “Versatile, Efficient and Longer Wagon for European Transportation”. The question is, does the result of the project fulfil the original target? Theoretically, the wagon has been constructed in the project. As a matter of fact, during the project time, also a real 80 ft wagon with 4 axles has been built by Tatravagonka, which is almost fulfils the requirements. It has the right length for 4 TEU but is approximately 10 cm too high to transport high-cube containers in some countries. But it has a high payload and allows flexible loading schemes of unit loads of different length. VEL-Wagon also received the “Green Corridor best project award” in Sweden 12-12-12 among 31 exhibitors. 
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  • Betancourt, Lazaro Hiram, et al. (författare)
  • The human melanoma proteome atlas-Defining the molecular pathology
  • 2021
  • Ingår i: Clinical and Translational Medicine. - : Wiley. - 2001-1326. ; 11:7, s. 1-20
  • Tidskriftsartikel (refereegranskat)abstract
    • The MM500 study is an initiative to map the protein levels in malignant melanoma tumor samples, focused on in-depth histopathology coupled to proteome characterization. The protein levels and localization were determined for a broad spectrum of diverse, surgically isolated melanoma tumors originating from multiple body locations. More than 15,500 proteoforms were identified by mass spectrometry, from which chromosomal and subcellular localization was annotated within both primary and metastatic melanoma. The data generated by global proteomic experiments covered 72% of the proteins identified in the recently reported high stringency blueprint of the human proteome. This study contributes to the NIH Cancer Moonshot initiative combining detailed histopathological presentation with the molecular characterization for 505 melanoma tumor samples, localized in 26 organs from 232 patients.
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5.
  • Betancourt, Lazaro, et al. (författare)
  • Quantitative Assessment of Urea In-Solution Lys-C/Trypsin Digestions Reveals Superior Performance at Room Temperature over Traditional Proteolysis at 37 °C.
  • 2018
  • Ingår i: Journal of Proteome Research. - : American Chemical Society (ACS). - 1535-3893 .- 1535-3907. ; 17:7, s. 2556-2561
  • Tidskriftsartikel (refereegranskat)abstract
    • Urea-containing buffer solutions are generally used in proteomic studies to aid protein denaturation and solubilization during cell and tissue lysis. It is well-known, however, that urea can lead to carbamylation of peptides and proteins and, subsequently, incomplete digestion of proteins. By the use of cells and tissues that had been lysed with urea, different solution digestion strategies were quantitatively assessed. In comparison with traditional proteolysis at 37 °C, urea in-solution digestion performed at room temperature improved peptide and protein identification and quantitation and had a minimum impact on miscleavage rates. Furthermore, the signal intensities and the number of carbamylated and pyroglutamic acid-modified peptides decreased. Overall, this led to a reduction in the negative effects often observed for such modifications. Data are available via ProteomeXchange with identifier PXD009426.
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6.
  • Sachs, Sven, et al. (författare)
  • Rare evidence of a giant pliosaurid-like plesiosaur from the Middle Jurassic (lower Bajocian) of Switzerland
  • 2019
  • Ingår i: SWISS JOURNAL OF PALAEONTOLOGY. - : SPRINGER HEIDELBERG. - 1664-2376 .- 1664-2384. ; 138:2, s. 337-342
  • Tidskriftsartikel (refereegranskat)abstract
    • Here, we describe part of a large-bodied macrophagous plesiosaur jaw from the lower Bajocian (Middle Jurassic) Passwang Formation near Arisdorf in the Basel-Land canton of Switzerland. The specimen preserves the posterior glenoid extremity of the right mandibular ramus comprising the surangular, angular, articular, and probably the prearticular. Notable character states include a transversely expanded surangular that incorporates a prominent medial ridge adjacent to the glenoid and a shallow dorsal fossa, together with a conspicuous trough extending across the lateral surfaces of both the surangular and angular; there is also a basally broad and medially deflected retroarticular process. Collectively, these features suggest affinities with Middle-Late Jurassic pliosaurids, as well as some coeval rhomaleosaurids. Based on such comparisons, we estimate that the Passwang Formation mandible was approximately 1.5 m long when complete, and thus approaches the size range of the largest-known pliosaurids. This discovery supplements the sparse record of diagnostic pliosaurid-like remains from Switzerland and contributes to the currently incomplete knowledge of pre-Callovian Middle Jurassic plesiosaurs globally.
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7.
  • Souza de Almeida, Jailton, et al. (författare)
  • Tuning the structural, electronic, and optical properties of BexZn1-xTe alloys
  • 2006
  • Ingår i: Applied Physics Letters. - : AIP Publishing. - 0003-6951 .- 1077-3118. ; 89:6, s. 061913-
  • Tidskriftsartikel (refereegranskat)abstract
    • A series of first principles calculations have been carried out to investigate structural, electronic, and optical properties of BexZn1-xTe alloys for five beryllium compositions. Our results show that the lattice constant scales linearly with beryllium composition and there is a direct-to-indirect band gap crossover nearly at the composition of 20%. It is also found that no bowing effect in the absorption edge is observed unlike other II-VI semiconductor alloys. Our results are in good qualitative agreements with experimental observations.
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