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- Andersson, Agneta, et al.
(författare)
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Domiciliary liquid oxygen versus concentrator treatment in chronic hypoxaemia: a cost-utility analysis
- 1998
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Ingår i: European Respiratory Journal. - 1399-3003. ; 12:6, s. 1284-1289
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Tidskriftsartikel (refereegranskat)abstract
- Whether long-term oxygen therapy (LTOT) improves quality of life in chronic hypoxaemia has been questioned. LTOT with an oxygen concentrator (C/C) and gas cylinders for ambulation is considered cumbersome compared to mobile liquid oxygen equipment (L). The hypothesis for this study was that LTOT with liquid oxygen treatment (L) improves patients' health-related quality of life, but that it is also more expensive compared to concentrator (C/C) treatment. A prospective, randomized multicentre trial comparing C/C with L for LTOT was conducted during a six-month period. Fifty-one patients (29 on L and 22 on C/C) with chronic hypoxaemia, regularly active outside the home, participated in the study initially. Costs for oxygen were obtained from the pharmacies. Patient diaries and telephone contacts with members of the healthcare sector were used to estimate costs. Health-related quality of life was measured by the Sickness Impact Profile (SIP) and the EuroQol, instruments at the start and after 6 months. The average total cost per patient for group C/C for the six-month period was US$1,310, and for group L it was US$4,950. Health-related quality of life measured by the SIP instrument showed significant differences in favour of group L in the categories/dimensions of physical function, body care, ambulation, social interaction and total SIP score. In conclusion, liquid-oxygen treatment was more expensive compared to concentrator treatment. However, treatment effects showed that liquid oxygen had a better impact on quality of life.
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| 2. |
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| 3. |
- Andersson, Arne, et al.
(författare)
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Ottenby fågelstation : Årsrapport 1999
- 1999
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Decenniets, seklets och milleniets sista år blev ett år av stora förändringar vid Ottenby fågelstation. Deföregående tre-fyra åren hade präglats av mycket dålig ekonomi och därtill personalproblem. Under 1998blev situationen akut. Som ett första led i att förbättra situationen ombildades Ottenbykommittén (avSveriges Ornitologiska Förening satt att sköta fågelstationen) under hösten 1998. Den störstaförändringen blev sedan att Jan Pettersson, platschef sedan 1978, sades upp. Därtill kom uppsägning,pensionering, dödsfall (se nedan) och sedan tidigare överflyttade tjänster till OFAB, vilket innebar detatt den “fast” anställda personalstyrkan, som 1992 var 7 personer, reducerades till noll!Ottenbykommittén har nu fått en mycket mer aktiv roll i stationens arbete. Olika verksamhetsdelar haridentifierats och ledamöterna har getts olika ansvarsområden.Kommittén bestod under året av :Åke Lindström (ordförande)Christian Hjort (sekreterare, utlandsverksamheten)Dennis Kraft (ekonomi)Arne Andersson (datafrågor)Dennis Hasselquist (samordning av ansökningar)Anders Hedenström (forskningssamordnare)Niclas Jonzén (personal)Lars Lindell (SOF:s styrelse).Aktiviteterna inom dessa olika områden redovisas nedan och här skallbara de generella linjerna i arbetet läggas fram.Tvivelsutan förbättrades arbetsklimatet för den ideellt arbetandepersonalen på fågelstationen och glädjande nog var tillströmningen storav arbetsvilliga ungdomar. Stationen blev på många sätt öppnare, inteminst mot fågelskådarleden. Fler personer besökte stationen och pådetta sätt kan många fler känna sig delaktiga och trivas. Nackdelen äratt det rent praktiskt blir svårare att driva verksamheten med mångamänniskor närvarande och relativt stor omsättning på personer.Genom mycket hård åtstramning på utgiftssidan kunde ett förväntat rejält underskott i budgeten vändastill en liten vinst. Alla inblandade skall ha stor ära av detta eftersom både stora som små uppoffringarkrävts för att styra ekonomin rätt. Den lilla vinsten användes till att börja täcka det underskott somunder många år ackumulerats. Även om det nu känns som att vi har en god kontroll över den löpandeekonomin så måste vi på lång sikt hitta fler finansieringskällor till stationens verksamhet. Det är tillexempel mycket otillfredsställande att vi nu inte har någon heltidsanställd personal, något som på siktmåste lösas.Fågelstationens gamla dröm om att ha en egen filial söder om Sahara gick i uppfyllelse under 1999 meden månads försöksverksamhet i Nigeria under våren. Denna slog väl ut på alla sätt och verksamhetenskall nu intensifieras under 2000.Datahanteringen fick sig en rejäl skjuts framåt under året och kan vi bara snart förnya maskinparken finnsgrunden för en smidig och effektiv datahantering vid stationen. Detta kommer att underlätta bådeutåtriktad verksamhet (Internet) och eget analysarbete.Ottenby Försäljnings AB (OFAB), som drivit den affärsmässiga delen av stationens verksamhet sedan1995, fortsatte sin verksamhet parallellt med fågelstationens ideella verksamhet. Genom verksamheten iNaturum och restaurang Fågel Blå svarar OFAB för en viktig del av fågelstationens publika aktiviteter.Det är av stor vikt för framtiden att behålla och utveckla det goda samarbetet mellan fågelstationen ochOFAB.Figur 1. Åke LindströmFigur 2. Patrik Rhönnstad, platschef 1999Kontinuiteten i det praktiska arbetet på stationen blev naturligtvis något lidande av att den rutineradepersonalen försvunnit. Situationen hjälptes dock upp signifikant av att OFABs personal fanns på plats(Håkan och Annika Lundkvist, Gösta Friberg) samt att nye platschefen och många av de ideelltarbetande hade erfarenhet från tidigare år.
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| 5. |
- Andersson, Agneta, et al.
(författare)
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Vertical transport of lipid in seawater
- 1993
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Ingår i: Marine Ecology Progress Series. - : Inter-Research Science Center. - 0171-8630 .- 1616-1599. ; 98:1-2, s. 149-155
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Tidskriftsartikel (refereegranskat)abstract
- Lipids in seawater act as solvents and transporters of lipophilic organic pollutants. To investigate a possible transport route of lipophilic pollutants, the vertical flux of lipid was quantified during an annual cycle in the northern Baltic Sea. The lipid content in both sedimenting material and different size fractions of seawater was analyzed. During the year, 8 g lipid m-2 sedimented out from the photic zone to the benthic system. The sedimentation of lipid accounted for 300 to 400 % of the average standing stock of pelagic lipid and was concentrated in the spring bloom period (April-June) when 70 % of the total lipid sedimentation occurred. About 30 % of the produced pelagic lipid settled out from the system. In seawater the lipid maximum occurred at the end of the spring bloom, shortly after nutrient depletion, indicating a stress response in the algae. Since lipid sedimentation is concentrated in the spring bloom, removal of lipophilic organic pollutants may be important during this period.
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| 7. |
- Andersson, Bert, 1952, et al.
(författare)
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Changes in early and late diastolic filling patterns induced by long-term adrenergic beta-blockade in patients with idiopathic dilated cardiomyopathy.
- 1996
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Ingår i: Circulation. - 0009-7322. ; 94:4, s. 673-82
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Tidskriftsartikel (refereegranskat)abstract
- beta-Blockers have been used in patients with idiopathic dilated cardiomyopathy to improve cardiac performance and theoretically would be beneficial to diastolic function. However, there are few reports on changes in diastolic function during chronic pharmacological treatment of congestive heart failure.The present study was a substudy in the international Metoprolol in Dilated Cardiomyopathy Trial. Transmitral Doppler echocardiography was used to evaluate diastolic function in 77 patients randomly assigned to placebo (n = 37) or metoprolol (n = 40). The patients were treated for 12 months. Changes in Doppler flow variables in the metoprolol group implied a less restrictive filling pattern, expressed as an increase in E-wave deceleration time (placebo, 185 +/- 126 to 181 +/- 64 ms; metoprolol, 152 +/- 63 to 216 +/- 78 ms; P = .01, placebo versus metoprolol). Maximal increase in deceleration time had occurred by 3 months, whereas systolic recovery was achieved gradually and maximal effect was seen by 12 months of treatment. Although deceleration time was correlated to heart rate at baseline, changes in deceleration time were not significantly correlated to changes in heart rate during treatment.During the first 3 months of treatment, maximal effects on diastolic variables were reached, whereas the most prominent effect on systolic function was seen late in the study. It is suggested that effects on diastolic filling account for subsequent later myocardial systolic recovery. The E-wave deceleration time, which in recent studies has been shown to be a powerful predictor of survival, was significantly improved in the metoprolol-treated patients.
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| 8. |
- Andersson, Bert, 1952, et al.
(författare)
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Improved exercise hemodynamic status in dilated cardiomyopathy after beta-adrenergic blockade treatment.
- 1994
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Ingår i: Journal of the American College of Cardiology. - 0735-1097. ; 23:6, s. 1397-404
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Tidskriftsartikel (refereegranskat)abstract
- This study was performed to investigate exercise hemodynamic status in a double-blind, placebo-controlled trial and was a substudy in the Metoprolol in Dilated Cardiomyopathy Trial.Previous open studies have shown beneficial effects on exercise hemodynamic status after beta-adrenergic blocking agent therapy in patients with congestive heart failure.The study included 41 patients with idiopathic dilated cardiomyopathy with ejection fraction < 0.40 (metoprolol, 20 patients; placebo, 21 patients) whose hemodynamic status was investigated at rest and during supine submaximal exercise, at baseline and after 6 and 12 months of treatment. Myocardial metabolism was evaluated in a subset of 19 patients.Metoprolol-treated patients responded favorably, as expressed by improved exercise cardiac index ([mean +/- SD] placebo 4.8 +/- 1.6 to 4.7 +/- 1.8 liters/min per m2, metoprolol 4.3 +/- 1.1 to 5.4 +/- 1.9 liters/min per m2, p = 0.0001) and stroke work index (placebo 44 +/- 20 to 41 +/- 27 g.m/m2, metoprolol 35 +/- 16 to 58 +/- 28 g.m/m2, p < 0.0001). Exercise systolic arterial pressure increased (placebo 161 +/- 25 to 151 +/- 23 mm Hg, metoprolol 155 +/- 29 to 165 +/- 37 mm Hg, p = 0.0003) as well as exercise oxygen consumption index (placebo 463 +/- 194 to 474 +/- 232 ml/min per m2, metoprolol 406 +/- 272 to 507 +/- 298 ml/min per m2, p = 0.045). There was a significant increase in exercise duration in the metoprolol group (63 +/- 38 s) compared with the placebo group (-24 +/- 42 s) (p = 0.01). Net myocardial lactate extraction increased in the metoprolol group, suggesting less myocardial ischemia (placebo 17 +/- 22 to 9.5 +/- 6.4 mmol/min, metoprolol -32 +/- 100 to 42 +/- 45 mmol/min, p = 0.03). Peripheral levels of norepinephrine tended to decrease at rest and during exercise, whereas myocardial net spillover was unchanged.Metoprolol improved hemodynamic status in patients with dilated cardiomyopathy at rest and had a more pronounced effect during exercise. These positive effects were achieved along with improved or stable myocardial metabolic data.
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| 9. |
- Andersson, Bengt-Åke, et al.
(författare)
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Bed-to-wall heat transfer in a 10m2 bubbling fluidized bed
- 1994
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Ingår i: Congreso Europeo de Fluidización. - 8478060936 ; 1, s. 251-260
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Konferensbidrag (refereegranskat)abstract
- The heat transfer is measured on the membrane tube wall in contact with a bubbling fluidized bed boiler. Measurements are carried out by heat transfer meters through holes in the wall both in the bed and above the bed in the splash zone and freeboard. Heat transfer coefficients are given and compared with previous measurements of material loss at the same wall and under the same conditions (typical for a fluidized bed boiler)
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| 10. |
- Andersson, Bengt-Åke, et al.
(författare)
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Experimental methods of estimating heat transfer in circulating fluidized bed boilers
- 1992
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Ingår i: International Journal of Heat and Mass Transfer. - 0017-9310. ; 35:12, s. 3353-3362
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Tidskriftsartikel (refereegranskat)abstract
- Four different experimental methods have been used for the estimation of the bed-to-membranewall heat transfer in a 12 MW,, circulating fluidized bed boiler. The methods are compared for a case ofnormal operating conditions and the measured heat transfer coefficients are presented. In the central partof the combustion chamber where most of the cooling surface is located, the cross-sectional averagesuspension density normally varies in the range of 10-20 kg m -’ and the heat transfer coefficient is around130 W m ’ K-’ with a scatter of + 15% due to the different methods. The methods are critically analyzedand the heat transfer data are compared with relevant literature data.
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