| 1. |
- Andersson, John Åke, et al.
(författare)
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Sweden's Economic Relationships with Uganda
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This explorative study aims to map commercial and other economic relations between Sweden and Uganda during the years 2000-2014. In addition, we will discuss whether and how these relations may be related to Swedish bilateral aid.
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| 2. |
- Ahlgren, Kerstin M, et al.
(författare)
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Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus
- 2014
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 9:8, s. e105473-
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Tidskriftsartikel (refereegranskat)abstract
- AIMS/HYPOTHESIS:Diabetes mellitus is one of the most common endocrine disorders in dogs and is commonly proposed to be of autoimmune origin. Although the clinical presentation of human type 1 diabetes (T1D) and canine diabetes are similar, the aetiologies may differ. The aim of this study was to investigate if autoimmune aetiology resembling human T1D is as prevalent in dogs as previously reported.METHODS:Sera from 121 diabetic dogs representing 40 different breeds were tested for islet cell antibodies (ICA) and GAD65 autoantibodies (GADA) and compared with sera from 133 healthy dogs. ICA was detected by indirect immunofluorescence using both canine and human frozen sections. GADA was detected by in vitro transcription and translation (ITT) of human and canine GAD65, followed by immune precipitation. Sections of pancreata from five diabetic dogs and two control dogs were examined histopathologically including immunostaining for insulin, glucagon, somatostatin and pancreas polypeptide.RESULTS:None of the canine sera analysed tested positive for ICA on sections of frozen canine or human ICA pancreas. However, serum from one diabetic dog was weakly positive in the canine GADA assay and serum from one healthy dog was weakly positive in the human GADA assay. Histopathology showed marked degenerative changes in endocrine islets, including vacuolisation and variable loss of immune-staining for insulin. No sign of inflammation was noted.CONCLUSIONS/INTERPRETATIONS:Contrary to previous observations, based on results from tests for humoral autoreactivity towards islet proteins using four different assays, and histopathological examinations, we do not find any support for an islet autoimmune aetiology in canine diabetes mellitus.
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| 3. |
- Andersson, C, et al.
(författare)
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The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes
- 2011
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Ingår i: Autoimmunity. - : Taylor & Francis. - 0891-6934 .- 1607-842X. ; 44:5, s. 394-405
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Tidskriftsartikel (refereegranskat)abstract
- Aims: We tested whether autoantibodies to all three ZnT8RWQ variants, GAD65, insulinoma-associated protein 2 (IA-2), insulin and autoantibodies to islet cell cytoplasm (ICA) in combination with human leukocyte antigen (HLA) would improve the diagnostic sensitivity of childhood type 1 diabetes by detecting the children who otherwise would have been autoantibody-negative.Methods: A total of 686 patients diagnosed in 1996–2005 in Skåne were analyzed for all the seven autoantibodies [arginin 325 zinc transporter 8 autoantibody (ZnT8RA), tryptophan 325 zinc transporter 8 autoantibody (ZnT8WA), glutamine 325 Zinc transporter 8 autoantibody (ZnT8QA), autoantibodies to glutamic acid decarboxylase (GADA), Autoantibodies to islet-antigen-2 (IA-2A), insulin autoantibodies (IAA) and ICA] in addition to HLA-DQ genotypes.Results: Zinc transporter 8 autoantibody to either one or all three amino acid variants at position 325 (ZnT8RWQA) was found in 65% (449/686) of the patients. The frequency was independent of age at diagnosis. The ZnT8RWQA reduced the frequency of autoantibody-negative patients from 7.5 to 5.4%—a reduction by 28%. Only 2 of 108 (2%) patients who are below 5 years of age had no autoantibody at diagnosis. Diagnosis without any islet autoantibody increased with increasing age at onset. DQA1-B1*X-0604 was associated with both ZnT8RA (p = 0.002) and ZnT8WA (p = 0.01) but not with ZnT8QA (p = 0.07). Kappa agreement analysis showed moderate (>0.40) to fair (>0.20) agreement between pairs of autoantibodies for all combinations of GADA, IA-2A, ZnT8RWQA and ICA but only slight ( < 0.19) agreement for any combination with IAA.Conclusions: This study revealed that (1) the ZnT8RWQA was common, independent of age; (2) multiple autoantibodies were common among the young; (3) DQA1-B1*X-0604 increased the risk for ZnT8RA and ZnT8WA; (4) agreement between autoantibody pairs was common for all combinations except IAA. These results suggest that ZnT8RWQA is a necessary complement to the classification and prediction of childhood type 1 diabetes as well as to randomize the subjects in the prevention and intervention of clinical trials.
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| 4. |
- Andersson, David Emanuel, et al.
(författare)
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Globalisation in stages
- 2017
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Ingår i: Economics of Globalisation. - : Taylor and Francis. - 9781351159326 - 9780815388715 ; , s. 77-93
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Andersson, David Emanuel, et al.
(författare)
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Phase transitions as a cause of economic development
- 2019
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Ingår i: Environment and planning A. - : Sage Publications. - 0308-518X .- 1472-3409. ; 51:3, s. 670-686
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Tidskriftsartikel (refereegranskat)abstract
- Economic development spans centuries and continents. Underlying infrastructural causes of development, such as institutions and networks, are subject to slow but persistent change. Accumulated infrastructural changes eventually become so substantial that they trigger a phase transition. Such transitions disrupt the prior conditions for economic activities and network interdependencies, requiring radically transformed production techniques, organizations and location patterns. The interplay of economic equilibria and structural changes requires a theoretical integration of the slow time scale of infrastructural change and the fast time scale of market equilibration. This paper presents a theory that encompasses both rapidly and slowly changing variables and illustrates how infrequent phase transitions caused four logistical revolutions in Europe over the past millennium.
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| 6. |
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| 7. |
- Andersson, D. E., et al.
(författare)
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Sustainability and the built environment : The role of durability
- 2019
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Ingår i: Sustainability. - : MDPI. - 2071-1050. ; 11:18
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Tidskriftsartikel (refereegranskat)abstract
- A sustainable city combines stable long-term economic growth with a resilient ecological system. It is also a region of social sustainability with low levels of spatial segregation of different socio-economic groups. Spatial inclusion primarily involves provision of equalized city-wide access to territorial public goods. High durability of physical networks and buildings facilitates economic, environmental and social sustainability. This study shows that durability varies considerably between Asian, European and North American cities, with mean life expectancies of buildings that range from below 20 years in Chinese cities to over 100 years in European cities such as Paris. Urban planning principles that focus on the slow and steady expansion of accessibility and density within a durable built environment are consistent with general economic equilibria, while avoiding the pitfalls of political planning of the markets for private goods.
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| 8. |
- Andersson, David Emanuel, et al.
(författare)
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Unemployment in European regions: structural problems versus the Eurozone hypothesis
- 2015
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Ingår i: Journal of Economic Geography. - Oxford University Press : Oxford University Press (OUP). - 1468-2702 .- 1468-2710. ; 15:5, s. 883-905
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Tidskriftsartikel (refereegranskat)abstract
- Unemployment rates differ dramatically across European regions. This article analyses these differences by integrating institutional and spatial perspectives into a unified dynamic framework distinguishing between slow and fast processes of change. The framework forms the basis for an econometric model that is used to analyse labour market differences among European Nomenclature des unités territoriales statistiques 2 regions. The results of random-effects models indicate that four key factors—all of which are of the slowly changing type—explain a large part of the variation in unemployment as well as employment rates. Flexible labour market regulations and above-average levels of interpersonal trust are institutional factors that reduce unemployment. Accessibility factors such as inter-regional transport connectivity and local access to skilled workers have similarly substantial effects. Whether a region belongs to the Eurozone or not seems to be less important.
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| 9. |
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| 10. |
- Andersson, Åke E., et al.
(författare)
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Creative cities and the new global hierarchy
- 2015
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Ingår i: Applied Spatial Analysis and Policy. - : Springer. - 1874-463X .- 1874-4621. ; 8:3, s. 181-198
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Tidskriftsartikel (refereegranskat)abstract
- The world experienced three major urbanization processes between the eleventh and the twentieth century. All three periods of city growth were associated with revolutionary improvements in the logistical systems. In large parts of the world the third logistical revolution (the Industrial Revolution) has not yet come to an end. In industrializing countries and regions urbanization is thus very rapid. Concurrently, a new and fourth logistical revolution is changing the economic, social and regional structure of the post-industrial parts of the world, leading to the creation of a new Creative Society. A key aspect of this development is the increasing role of creative and innovative city regions with global linkages. These regions now form a new supranational rank-size distribution, which is centred on a few conurbations in Europe, North America and East Asia. Most post-industrial economic development is taking place in a small number of highly ranked creative regions, while other regions are suffering from the “creative destruction” of their traditional industries. One consequence of this restructuring is increasing regional income inequalities in the post-industrial nations.
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