| 1. |
- Andersson, John Åke, et al.
(författare)
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Sweden's Economic Relationships with Uganda
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This explorative study aims to map commercial and other economic relations between Sweden and Uganda during the years 2000-2014. In addition, we will discuss whether and how these relations may be related to Swedish bilateral aid.
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| 2. |
- Ahlgren, Kerstin. M, et al.
(författare)
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Diabetes mellitus in dog - : No evidence for a type-1-like phenotype
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Aims/hypothesis Diabetes mellitus (DM) is one of the most common endocrine disorders in dogs, and is commonly proposed to be of autoimmune origin. Although the clinical symptoms of human type 1 diabetes (T1D) and canine DM are similar, the aetiologies may differ. The aim of this study was to investigate if autoimmune aetiology resembling human T1D is as prevalent in dogs as previously reported. Methods Sera from 121 diabetic dogs representing 38 different breeds were tested for islet cell antibodies (ICA) and GAD65 autoantibodies (GADA) and compared with sera from 133 healthy dogs from 40 breeds. ICA was detected by indirect immunofluorescence using both canine and human frozen sections. GADA was detected by in vitro transcription and translation (ITT) of human and canine GAD65, followed by immunoprecipitation. Results None of the canine sera analyzed tested positive for ICA on sections of frozen canine or human ICA pancreas. However, serum from one diabetic dog was weakly positive in the canine GADA assay and serum from one healthy dog was weakly positive in the human GADA assay. Conclusions/interpretations Based on sera from 121 diabetic dogs from 38 different breeds were tested for humoral autoreactivity using four different assays, contrary to previous observations, we find no support for an autoimmune aetiology in canine diabetes.
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| 3. |
- Ahlgren, Kerstin M, et al.
(författare)
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Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus
- 2014
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 9:8, s. e105473-
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Tidskriftsartikel (refereegranskat)abstract
- AIMS/HYPOTHESIS:Diabetes mellitus is one of the most common endocrine disorders in dogs and is commonly proposed to be of autoimmune origin. Although the clinical presentation of human type 1 diabetes (T1D) and canine diabetes are similar, the aetiologies may differ. The aim of this study was to investigate if autoimmune aetiology resembling human T1D is as prevalent in dogs as previously reported.METHODS:Sera from 121 diabetic dogs representing 40 different breeds were tested for islet cell antibodies (ICA) and GAD65 autoantibodies (GADA) and compared with sera from 133 healthy dogs. ICA was detected by indirect immunofluorescence using both canine and human frozen sections. GADA was detected by in vitro transcription and translation (ITT) of human and canine GAD65, followed by immune precipitation. Sections of pancreata from five diabetic dogs and two control dogs were examined histopathologically including immunostaining for insulin, glucagon, somatostatin and pancreas polypeptide.RESULTS:None of the canine sera analysed tested positive for ICA on sections of frozen canine or human ICA pancreas. However, serum from one diabetic dog was weakly positive in the canine GADA assay and serum from one healthy dog was weakly positive in the human GADA assay. Histopathology showed marked degenerative changes in endocrine islets, including vacuolisation and variable loss of immune-staining for insulin. No sign of inflammation was noted.CONCLUSIONS/INTERPRETATIONS:Contrary to previous observations, based on results from tests for humoral autoreactivity towards islet proteins using four different assays, and histopathological examinations, we do not find any support for an islet autoimmune aetiology in canine diabetes mellitus.
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| 4. |
- Andersson, David Emanuel, et al.
(författare)
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Globalisation in stages
- 2017
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Ingår i: Economics of Globalisation. - : Taylor and Francis. - 9781351159326 - 9780815388715 ; , s. 77-93
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Andersson, David Emanuel, et al.
(författare)
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Infrastructural change and secular economic development
- 2008
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Ingår i: Technological forecasting & social change. - : Elsevier BV. - 0040-1625 .- 1873-5509. ; 75:6, s. 799-816
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Tidskriftsartikel (refereegranskat)abstract
- Long-term economic development is determined by changes to the infrastructure, especially material and non-material infrastructural networks that link agents in different locations. The infrastructure consists of the slowly changing, collective arena that supports production, exchange, and consumption, such as the built environment, transport networks, and institutions. In the short run the infrastructure can be regarded as fixed. Changes to the infrastructure are under normal conditions small enough to be disregarded by producers and consumers. With the creation of a critical link of a network, there will however be a revolutionary restructuring of the arena. Critical links are here defined as additions to infrastructural networks that create opportunities for new information and transport flows between previously unconnected regions. Such a revolutionary restructuring of infrastructural networks has been called a logistical revolution. Certain institutional pre-conditions are necessary for a logistical revolution, while the creation of a critical link is both a necessary and a sufficient condition. This paper discusses the three logistical revolutions that occurred in the 13th century, around 1600, and in the 19th century, which each had crucial similarities with the current “information revolution.”
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| 6. |
- Andersson, David Emanuel, et al.
(författare)
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Phase transitions as a cause of economic development
- 2019
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Ingår i: Environment and planning A. - : Sage Publications. - 0308-518X .- 1472-3409. ; 51:3, s. 670-686
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Tidskriftsartikel (refereegranskat)abstract
- Economic development spans centuries and continents. Underlying infrastructural causes of development, such as institutions and networks, are subject to slow but persistent change. Accumulated infrastructural changes eventually become so substantial that they trigger a phase transition. Such transitions disrupt the prior conditions for economic activities and network interdependencies, requiring radically transformed production techniques, organizations and location patterns. The interplay of economic equilibria and structural changes requires a theoretical integration of the slow time scale of infrastructural change and the fast time scale of market equilibration. This paper presents a theory that encompasses both rapidly and slowly changing variables and illustrates how infrequent phase transitions caused four logistical revolutions in Europe over the past millennium.
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| 7. |
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| 8. |
- Andersson, D. E., et al.
(författare)
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Sustainability and the built environment : The role of durability
- 2019
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Ingår i: Sustainability. - : MDPI. - 2071-1050. ; 11:18
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Tidskriftsartikel (refereegranskat)abstract
- A sustainable city combines stable long-term economic growth with a resilient ecological system. It is also a region of social sustainability with low levels of spatial segregation of different socio-economic groups. Spatial inclusion primarily involves provision of equalized city-wide access to territorial public goods. High durability of physical networks and buildings facilitates economic, environmental and social sustainability. This study shows that durability varies considerably between Asian, European and North American cities, with mean life expectancies of buildings that range from below 20 years in Chinese cities to over 100 years in European cities such as Paris. Urban planning principles that focus on the slow and steady expansion of accessibility and density within a durable built environment are consistent with general economic equilibria, while avoiding the pitfalls of political planning of the markets for private goods.
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| 9. |
- Andersson, David Emanuely, et al.
(författare)
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The geography of science in 12 European countries : a NUTS2-level analysis
- 2020
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Ingår i: Scientometrics. - : Springer Nature. - 0138-9130 .- 1588-2861. ; 124:2, s. 1099-1125
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Tidskriftsartikel (refereegranskat)abstract
- Europe has a long history as a global center of scientific research, but not all European regions are alike. Regions such as ile de France and the corridor that stretches from Cambridge to Oxford via London produce a disproportionate share of Europe's science output. An econometric analysis sheds light on the factors that explain the spatial distribution of European science. One result is that the regional volume of Web of Science publications depends on the regional number of researchers in higher education institutions. This is however not the only cause of high output. Universities and their surrounding regions are slowly evolving institutional structures. Some regions host universities that are more than 500 years old. A second key result is that an increase in the age of a region's oldest university is associated with greater output, other things being equal. Third, interregional accessibility via road, rail, and air networks is important for small regions, but not for large ones. Conversely, regional high-tech R&D employment is important for large but not for small regions.
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| 10. |
- Andersson, D. E., et al.
(författare)
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The impossibility of the triple helix
- 2020
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Ingår i: Prometheus. - : Pluto Journals. - 0810-9028 .- 1470-1030. ; 36:3, s. 235-252
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Tidskriftsartikel (refereegranskat)abstract
- A dynamic model that distinguishes between slow and fast processes shows that a triple helix model is impossible as a tool for promoting interdependencies among science, industry and government. We present a theorem to demonstrate that a triple helix strategy is logically impossible as a means of funding scientific research in universities. In spite of this logical impossibility, national and regional triple helix strategies to improve productivity and innovative capacity have been favoured by politicians of almost every ideological stripe. Coordination of science and industry by governments is not new; it harks back to the mercantilism of seventeenth-century Britain and France. In the twentieth and twenty-first centuries, triple helix policies have led to a short-term bias in favour of applied technological research. Several examples, ranging from the military use of scientists in World War II to Chinese high technology parks show how triple helix strategies tilt playing fields, suppress academic freedom0 and expose scientists to the whims of politicians.
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