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Träfflista för sökning "WFRF:(Andersson Helena 1966) srt2:(2015-2019)"

Sökning: WFRF:(Andersson Helena 1966) > (2015-2019)

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Numrering	Referens	Omslagsbild	Hitta
1.	Granfors, Michaela, et al. (författare) Iodine deficiency in a study population of pregnant women in Sweden 2015 Ingår i: Acta Obstetricia Et Gynecologica Scandinavica. - : Wiley. - 0001-6349 .- 1600-0412. ; 94:11, s. 1168-1174 Tidskriftsartikel (refereegranskat)abstract IntroductionIodine deficiency in utero may impair neurological development of the fetus. In Sweden, iodine nutrition is considered to be adequate in the general population. The aim of this study was to evaluate iodine nutrition during pregnancy in Sweden. Material and methodsIn this cross-sectional study, the total study population (n=459) consisted of two cohorts (Varmland County, n=273, and Uppsala County, n=186) of pregnant non-smoking women without pre-gestational diabetes mellitus or known thyroid disease before or during pregnancy. Spot urine samples were collected in the third trimester of pregnancy for median urinary iodine concentration (UIC) analysis. ResultsThe median UIC in the total study population was 98g/L (interquartile range 57-148g/L). ConclusionsAccording to WHO/UNICEF/IGN criteria, population-based median UIC during pregnancy should be 150-249g/L. Thus, our results indicate insufficient iodine status in the pregnant population of Sweden. There is an urgent need for further assessments in order to optimize iodine nutrition during pregnancy.
2.	Manousou, Sofia, 1979, et al. (författare) Iodine deficiency emerges among pregnant women in Sweden despite salt iodine fortification at 50 ppm-a national, cross-sectional study 2017 Ingår i: 87th Annual Meeting of the American Thyroid Association, October 18-22, 2017, Victoria, BC, Canada. - : Mary Ann Liebert Inc. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
3.	Satizabal, Claudia L., et al. (författare) Genetic architecture of subcortical brain structures in 38,851 individuals 2019 Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 51:11, s. 1624- Tidskriftsartikel (refereegranskat)abstract Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus, using genome-wide association analyses in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank. We show that variability in subcortical volumes is heritable, and identify 48 significantly associated loci (40 novel at the time of analysis). Annotation of these loci by utilizing gene expression, methylation and neuropathological data identified 199 genes putatively implicated in neurodevelopment, synaptic signaling, axonal transport, apoptosis, inflammation/infection and susceptibility to neurological disorders. This set of genes is significantly enriched for Drosophila orthologs associated with neurodevelopmental phenotypes, suggesting evolutionarily conserved mechanisms. Our findings uncover novel biology and potential drug targets underlying brain development and disease.

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Typ av publikation: tidskriftsartikel (2); konferensbidrag (1)

Typ av innehåll: refereegranskat (2); övrigt vetenskapligt/konstnärligt (1)

Författare/redaktör: Nyström, Helena Fili ... (2); Franke, Barbara (1); Westman, Eric (1); Tsolaki, Magda (1); Ching, Christopher R ... (1); Agartz, Ingrid (1); visa fler...; Brouwer, Rachel M (1); Melle, Ingrid (1); Westlye, Lars T (1); Thompson, Paul M (1); Andreassen, Ole A (1); Andersson, M (1); Loeffler, Markus (1); Andersson, Micael (1); Axelsson, Tomas (1); Skalkidou, Alkistis (1); Andersson, Maria (1); van der Wee, Nic J. ... (1); Sundström Poromaa, I ... (1); Ikram, M. Arfan (1); Amin, Najaf (1); van Duijn, Cornelia ... (1); Chen, Qiang (1); Rotter, Jerome I. (1); Soininen, Hilkka (1); Wikström, Anna-Karin (1); Weinberger, Daniel R (1); Eggertsen, Robert, 1 ... (1); de Geus, Eco J. C. (1); Martin, Nicholas G. (1); Boomsma, Dorret I. (1); Heslenfeld, Dirk J. (1); van der Meer, Dennis (1); Djurovic, Srdjan (1); Doan, Nhat Trung (1); Meyer-Lindenberg, An ... (1); Thalamuthu, Anbupala ... (1); Cichon, Sven (1); Rietschel, Marcella (1); Schofield, Peter R (1); Schmidt, Reinhold (1); Schmidt, Helena (1); Deary, Ian J (1); Mattheisen, Manuel (1); Hulthén, Lena, 1947 (1); Nyberg, Lars, 1966- (1); Jönsson, Erik G. (1); Wassink, Thomas H (1); Lopez, Oscar L. (1); Montgomery, Grant W. (1); visa färre...

Lärosäte: Göteborgs universitet (2); Uppsala universitet (2); Karolinska Institutet (2); Umeå universitet (1)

Språk: Engelska (3)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (3)

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