| 1. |
- Alvarado-Kristensson, Maria, et al.
(författare)
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Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3.
- 2005
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Ingår i: Journal of Biological Chemistry. - 1083-351X. ; 280:7, s. 6238-6244
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Tidskriftsartikel (refereegranskat)abstract
- The induction of apoptosis in neutrophils is an essential event in the resolution of an inflammatory process. We found recently that the reduction of the activity of the neutrophil survival factor p38 MAPK and dephosphorylation and thus activation of caspases must occur to initiate such cell death in these leukocytes. Here, we report a previously undetected early and transient activation of protein phosphatase 2A WPM in neutrophils undergoing apoptosis. The pharmacological inhibition of this phosphatase during Fas-induced apoptosis augmented the levels of phosphorylation of both p38 MAPK and caspase 3, resulting in a decreased activity of caspase 3 and an increased neutrophil survival. The complementary finding of a time-dependent association among PP2A, p38 MAPK, and caspase 3 in intact neutrophils indicated that there is a direct regulatory link among these signaling enzymes during Fas-provoked apoptosis. Moreover, immunoprecipitated active p38 MAPK and recombinant phosphorylated caspase 3 were dephosphorylated by exposure to purified PP2A in vitro. Consequently, the early and temporary activation of PP2A in neutrophils impaired not only the p38 MAPK-mediated inhibition of caspase 3 but also restored the activity to caspase 3 that had already been phosphorylated and thereby inactivated. These findings indicate that PP2A plays a pivotal dual role in the induction of neutrophil apoptosis and therefore also in the resolution of inflammation.
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| 2. |
- Andersson, Gunvor, et al.
(författare)
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Teenagers as victims in the press
- 2007
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Ingår i: Children & Society. - : Wiley. - 0951-0605. ; 21:3, s. 175-188
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Tidskriftsartikel (refereegranskat)abstract
- Research into press reporting on young people has tended to concentrate on young people as offenders. In contrast, this article focuses on press coverage of teenagers as victims. Reports in two Swedish newspapers (a morning broadsheet and an evening tabloid) were studied over a period of four months and subjected to a qualitative analysis of discourse on teenagers as victims of various forms of violence and ill-treatment. It was found that danger and threats to the teenagers were seen as gendered, and as emanating from their own age group and from outside the home and family. The class background of the victims was not salient and child welfare issues were seldom mentioned.
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| 3. |
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| 4. |
- Andersson, Gunnel, 1955-
(författare)
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Vardagsliv och boendestöd : En studie om människor med psykiska funktionshinder
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In the wake of deinstitutionalization, people with psychiatric disabilities are, to a great extent, living in the community. In this thesis everyday life of people with psychiatric disabilities, living in independent housing with community-based social support to manage their daily life, is investigated. Special attention is paid to the characteristics and meaning of community-based social support. Through participating observational studies, interviews and time-geographic diaries, data have been gathered about everyday life of seventeen men and women. It is the interpersonal social conditions that have been the main target of the study, addressed as social networks and social support. Everyday life conditions are dependent on social as well as physical and material circumstances. Although the social conditions are emphasized in the study they are not looked upon as isolated dimensions but as part of everyday life circumstances. The everyday life perspective offers an opportunity to reveal the structures within which everyday life takes place. The time-geographic concepts “community-organized projects” and “individual-organized projects” were used to investigate the structures of everyday life, resulting in four substructures. Four types of everyday life and four patterns of networks connected to the different substructures were identified, showing great variations. The characteristics of community-based social support can be summarized as “the doing”, “the talking” and “the being with” in a reciprocal type of relationship. The meaning of support is shortly described as solution of and relieving problems, social companionship, security, protection and control. Community-based social support show similar importance regardless of the type of everyday life when it comes to solution of problems and different importance when it comes to aspects of support such as social companionship.
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| 5. |
- Andersson, Maria, 1977, et al.
(författare)
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Effects of consistency and accurate predictions of stock prices on herding in a simulated financial market.
- 2008
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Ingår i: Poster presented at the 29th annual conference of the Society for Judgment and Decision Making, Chicago, USA..
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- In a simulated financial market setting we investigate the degree to which participants in judgment tasks were influenced by other (fictitious) participants’ judgments. Two experiments examine the influence from random vs. accurate majorities (Experiment 1), random vs. accurate minorities (Experiment 2), and whether the influence was affected by instructing participants to focus on the accuracy in performance (Experiments 1 and 2). Results show that participants followed majorities irrespectively of their level of accuracy, whereas accurate minorities were more influential than random minorities. The focus instruction decreased majority influence, regardless of accuracy, but increased the influence from accurate minorities.
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| 6. |
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| 7. |
- Andersson, Maria, 1977, et al.
(författare)
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Effects of financial incentives on herding in simulated financial markets
- 2008
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Ingår i: Paper presented at the International Association for Research in Economic Psychology (IAREP), Rome, Italy..
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Konferensbidrag (refereegranskat)abstract
- Herding in financial markets refers to that investors influence each other when making investment decisions. In these experimental studies, herding leads to worse performance relative to relying on private information. Previous studies of herding have shown that majorities in general are more influential than minorities. The aim of this research was to investigate whether financial incentives impact herding with majorities and minorities under these conditions. In two experimental simulations of a financial market, participants predicted an “upmarket” or “downmarket” conditional on diagnostic information presented on each trial. In Experiment 1, participants in an individual condition only received private information, while participants in a group condition, in addition, received information about randomly generated predictions ostensibly made by three others. Economic incentives for accurate predictions were based on individual performance, and were hypothesized to counteract reliance on invalid information about the herd’s choices. As expected, performance was worse in the group condition than in the individual condition, implying that participants were influenced by the herd. In Experiment 2, the effects of financial incentives for making predictions similar to either the majority or the minority of the others were examined. We hypothesized that financially rewarding group performance may reinforce non-systematic processing, and hence enhance majority influence. Since minority influence is associated with systematic processing, we hypothesized that systematic processing in minority conditions may increase the influence of the private information, and thus improve performance. The results showed that participants followed the majority but not the minority. One explanation for the asymmetry in the effects of rewarding herding with a majority and a minority may be the notion that the tendency to conform overrides systematic processing in majority influence, whereas the reverse would be true in minority influence.
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| 8. |
- Andersson, Maria, 1977, et al.
(författare)
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Experimental Studies of Majority Influences in Financial Markets.
- 2008
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Ingår i: Paper presented at the 6th Nordic conference on group and social psychology (GRASP), Lund University, Sweden.
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Konferensbidrag (refereegranskat)abstract
- Herding in financial markets refers to that investors imitate others when making investment decisions. The aim of this research is to investigate factors that would break influences of a majority of others. In one experiment we investigate the impact of the size of a herd (majority vs. minority), accuracy of the herds’ predictions, and attentional focus. Undergraduates serving as participants are asked to predict fictitious stock prices in 50 trials, conditional on information about the current price and predictions made by five fictitious other participants. The prices and the others’ predictions are generated by random sampling. A majority of the others’ predictions is correlated (rs .95), and the predictions made by the majority are either random (uncorrelated with the price, r <.20) or accurate (correlated with the price, range of rs equal to .65 - .85). Participants are instructed to focus their attention on either accuracy or consistency of the others’ predictions. The results showed that a focus on accuracy reduced majority influence, whereas a focus on consistency had no effect. This was true both in the conditions with accurate and inaccurate majorities. An ongoing additional experiment investigates whether an accurate minority has an influence when its predictions have higher predictive validity than the price. The level of accuracy in the predictions made by the minority is either random (uncorrelated with the price, r <.20) or accurate (correlated with the price, rs .95).
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| 9. |
- Andersson, Maria, 1977, et al.
(författare)
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Social influence on predictions of simulated stock prices
- 2009
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Ingår i: Journal of Behavioral Decision Making. ; 22, s. 271-279
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Tidskriftsartikel (refereegranskat)abstract
- Herding in financial markets refers to that investors are influenced by others. This study addresses the importance of consistency for herding. It is suggested that, in financial markets perceptions of consistency are based on repeated observations over time. Consistency may then be perceived as the agreement across time between investors’ predictions. In addition, consistency may be related to variance over time in each investor’s predictions. In an experiment using a Multiple Cue Probability Learning paradigm, 96 undergraduates made multi-trial predictions of future stock prices given information about the current price and the predictions made by five fictitious others. Consistency was varied between the others' predictions (correlation) and within the others’ predictions (variance). The results showed that the predictions were significantly influenced by the others’ predictions when these were correlated. No effect of variance was observed. Hence, participants were influenced by the others when they were in agreement, regardless of whether they varied their predictions over trials or not.
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| 10. |
- Andersson, Maria, 1977, et al.
(författare)
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The effect of accuracy and focus on herding in financial predictions.
- 2008
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Ingår i: Paper presented at the 10th meeting of the European Social Cognition Network (ESCON), Volterra, Italy..
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Konferensbidrag (refereegranskat)abstract
- Herding in financial markets refers to that investors influence each other when making investment decisions. Previous studies of herding have shown that a majority is more influential than a minority. This result is in line with theories of social influence, arguing that majorities in general are more influential but consistent minorities may also exert influence. The aim of this research is to investigate what factors may impact the level of influence from minorities and majorities in financial markets, focusing on accuracy and focal attention. Experiment 1 investigates the impact of the size of the herd (majority vs. minority) and the accuracy in its predictions. Participants’ task was to predict fictitious stock prices in 50 trials, conditional on information about the current price and predictions made by five fictitious other participants. Either four (majority) or two (minority) of the others’ predictions were correlated (rs > .95), and they made either random (uncorrelated with the price trend, rs < .20) or non-random predictions (correlated with the price trend, range of rs equal to .65 to .85). The results showed that the majority exerted more influence than did the minority, more when the majority made non-random than random predictions. The correlation and accuracy of predictions thus increased the majority influence, but not the minority influence. The aim of Experiment 2 was to investigate whether the majority influence would decrease if participants were instructed to focus on the others’ performance. Conditions in which the majority made random or non-random predictions were included. After a number of trials participants were requested to state either which of the others that made accurate predictions or which of the others that made predictions that were correlated. The results showed that focus on accuracy reduced majority influence.
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