| 1. |
- Sunn Pedersen, Thomas, et al.
(författare)
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Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X
- 2022
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 0029-5515 .- 1741-4326. ; 62:4, s. 042022-042022
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Tidskriftsartikel (refereegranskat)abstract
- We present recent highlights from the most recent operation phases of Wendelstein 7-X, the most advanced stellarator in the world. Stable detachment with good particle exhaust, low impurity content, and energy confinement times exceeding 100 ms, have been maintained for tens of seconds. Pellet fueling allows for plasma phases with reduced ion-temperature-gradient turbulence, and during such phases, the overall confinement is so good (energy confinement times often exceeding 200 ms) that the attained density and temperature profiles would not have been possible in less optimized devices, since they would have had neoclassical transport losses exceeding the heating applied in W7-X. This provides proof that the reduction of neoclassical transport through magnetic field optimization is successful. W7-X plasmas generally show good impurity screening and high plasma purity, but there is evidence of longer impurity confinement times during turbulence-suppressed phases.
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| 2. |
- Andreeva, S, et al.
(författare)
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Case Report: Two New Cases of Autosomal-Recessive Hypertrophic Cardiomyopathy Associated With TRIM63-Compound Heterozygous Variant
- 2022
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Ingår i: Frontiers in genetics. - : Frontiers Media SA. - 1664-8021. ; 13, s. 743472-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Hypertrophic cardiomyopathy (HCM) is one of the most common hereditary diseases, and it is associated with fatal complications. The clinical heterogeneity of HCM requires risk prediction models to identify patients at a high risk of adverse events. Most HCM cases are caused by mutations in genes encoding sarcomere proteins. However, HCM is associated with rare genetic variants with limited data about its clinical course and prognosis, and existing risk prediction models are not validated for such patients’ cohorts. TRIM63 is one of the rare genes recently described as a cause of HCM with autosomal-recessive inheritance. Herein, we present two cases of HCM associated with TRIM63-compound heterozygous variants in young male sportsmen. They demonstrated progressively marked hypertrophy, advanced diastolic dysfunction, a significant degree of fibrosis detected by magnetic resonance imaging, and clear indications for implantable cardioverter-defibrillator. One of the cases includes the first description of TRIM63-HCM with extreme hypertrophy. The presented cases are discussed in light of molecular consequences that might underlie cardiac and muscle phenotype in patients with mutations of TRIM63, the master regulator of striated muscle mass.
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| 3. |
- Baulin, R. A., et al.
(författare)
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Unique surface sensitivity to ferro- and antiferromagnetic phases by polarization analysis in synchrotron Mossbauer reflectivity
- 2021
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Ingår i: SURFACES AND INTERFACES. - : Elsevier. - 2468-0230. ; 27
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Tidskriftsartikel (refereegranskat)abstract
- Polarization analysis of the reflected radiation has been performed in Mossbauer reflectivity measurements with a Synchrotron Mossbauer Source (SMS). Effective pi ->sigma' polarization selection is attained with LiF crystal ((6 2 2) 90 degrees-reflection for 14.4 keV radiation, angular acceptance similar to 100 '') capable of high pi ->pi' suppression. Basic features of the reflectivity with the rotated pi ->sigma' polarization are revealed in the experiment with the [Fe-57(10 ML)/V(20 ML)](20) multilayer. Selection of pi ->sigma' polarization component in Mossbauer reflectivity allows to exclude nonresonant electronic scattering, besides Mossbauer pi ->sigma' reflectivity spectra (R-spectra) contain only contributions from magnetized along the beam ferromagnetic phases. The antiferromagnetic iron oxides do not contribute to pi ->sigma' R-spectra (dichroic component is compensated). Therefore, in the Mossbauer reflectivity experiment supplemented by polarization analysis the data interpretation becomes more certain and gives information about depth position for ferromagnetic layers selectively. With this new technique we locate antiferromagnetic iron phases in the very top layer of [Fe-57(10 ML)/V(20 ML)](20) multilayer and ascertain the ferromagnetic ordered iron layers in the remaining part of the structure. This new approach in Mossbauer reflectivity has interesting perspectives for investigations of hyperfine interactions for iron complexes on the surface, ultrathin layers and multilayers with complicated magnetic structures.
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