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Sökning: WFRF:(Ashraf M) > (2005-2009)

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1.
  • van den Dool, Annemieke, et al. (författare)
  • The future is distributed: a vision of sustainable economies
  • 2009
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • “The Future is distributed: a vision of sustainable economies” is a collection of case studies on distributed economies, a concept describing sustainable alternatives to the existing business models. The authors of this publication are international Masters students of the Environmental Sciences, Policy and Management Programme at the International Institute for Industrial Environmental Economics at Lund University in Sweden. The aim of their work is to demonstrate that local, small-scale, community-based economies are not just part of the theory, but have already been implemented in various sectors and geographical settings.
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  • Zakey, Ashraf, et al. (författare)
  • Seasonal and spatial variation of atmospheric particulate matter in a developing megacity, the Greater Cairo, Egypt
  • 2008
  • Ingår i: Atmósfera. ; 21:2, s. 171-189
  • Tidskriftsartikel (refereegranskat)abstract
    • As an example of a developing megacity the Greater Cairo (GC) area in Egypt has been evaluated with respect to atmospheric particulate matter (PM) and lead (Pb). Particulate matter was collected during 2001-2002 in the two size fractions PM2.5 and PM10 at 17 sites representing different activities (industrial, urban, residential and background condition). The PM concentrations were generally high, with yearly average PM2.5 and PM10 values of 85 ± 12 and 170 ± 25 μg/m-3, respectively. On an annual scale, the high PM levels were due to many sources that included traffic, waste burning and wind blown dust particles emitted from the desert outside GC and the Moqattam hill inside GC. On a seasonal scale, the PM concentrations were highest in the industrial sector during spring, the dusty season, due to the combined effect of dust storm events and anthropogenic emissions over GC. The lowest seasonal concentrations were recorded in the summer season at the background sites. There was a marked increase in PM levels during the period Octoberto December due to burning of waste from harvested rice in the agriculture area in the Nile Delta (north of Cairo). The highest PM2.5/PM10 ratio was recorded in the urban sector (0.59) while the lowest ratio was recorded in the residential sector (0.32). The PM2.5 and PM10 samples were also analyzed for Pb in order to address the influence of different emission sources. The monthly average concentrations of Pb in both PM2.5 (Pb2.5) and PM10 (Pb10) varied between 0.4 and 1.8 ± μg m-3 at the non industrial sites. The concentrations were significantly higher in the industrial areas, where concentration up to a maximum of 16 ± g m-3 could be observed. Both the high lead and PM concentrations measured are contributing to local environmental pollution. GC is subjected to high concentrations of particulates most of the year. There is no annual limit for PM10 concentrations in the Egyptian law of environment, but comparing to the 24 hour average, PM10 is representing health risks on the long-term that will give both regionally and globally environmental effects. High volume samplers measuring PM10 as daily average shows that the air quality limit value has been exceeded at sites Heliopolis (35), Maadi (6) and 6th October (13) during 60.47, 79.07, and 62.96% of the measuring period of 2001, and at Shoubra El-Kheima (20), El-Qolaly Sq (1), and Abbasiya (36) during 100.0, 91.7, and 89.8% of the measuring period of 2002. Thus, the evaluation of the data presented in this paper will serve as a basis for future regional and global modelling and source apportionment.
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  • Ashraf, Ali, et al. (författare)
  • Self-reported use of tobacco products in nine rural INDEPTH Health and Demographic Surveillance Systems in Asia
  • 2009
  • Ingår i: Global Health Action. - : Taylor & Francis. - 1654-9716 .- 1654-9880. ; 2, s. 19-27
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Tobacco use is the most preventable cause of premature death and disability. Even though tobacco use is common in many Asian countries, reliable and comparable data on the burden imposed by tobacco use in this region are sparse, and surveillance systems to track trends are in their infancy.OBJECTIVE: To assess and compare the prevalence of tobacco use and its associated factors in nine selected rural sites in five Asian countries.METHODS: Tobacco use among 9,208 men and 9,221 women aged 25-64 years in nine Health and Demographic Surveillance System (HDSS) sites in five Asian countries of the INDEPTH Network were examined in 2005 as part of a broader survey of the major chronic non-communicable disease risk factors. All sites used a standardised protocol based on the WHO STEPS approach to risk factor surveillance; expanded questions of local relevance, including chewing tobacco, were also included. Multivariable logistic regression was used to assess demographic factors associated with tobacco use.RESULTS: Tobacco use, whether smoked or chewed, was common across all sites with some notable variations. More than 50% of men smoked daily; this applied to almost all age groups. Few women smoked daily in any of the sites. However, women were more likely to chew tobacco than men in all sites except Vadu in India. Tobacco use in men began in late adolescence in most of the sites and the number of cigarettes smoked daily ranged from three to 15. Use of both forms of tobacco, smoked and chewed, was associated with age, gender and education. Men were more likely to smoke compared to women, smoking increased with age in the four sites in Bangladesh but not in other sites and with low level of education in all the sites.CONCLUSION: The prevalence of tobacco use, regardless of the type of tobacco, was high among men in all of these rural populations with tobacco use started during adolescence in all HDSS sites. Innovative communication strategies for behaviour change targeting adolescents in schools and adult men and women at work or at home, may create a mass awareness about adverse health consequences of tobacco smoking or chewing tobacco. Such efforts, to be effective, however, need to be supported by strong legislation and leadership. Only four of the five countries involved in this multi-site study have ratified the Framework Convention on Tobacco Control, and even where it has been ratified, implementation is uneven.
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  • Ma, Li-Jun, et al. (författare)
  • Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication.
  • 2009
  • Ingår i: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404. ; 5:7, s. e1000549-
  • Tidskriftsartikel (refereegranskat)abstract
    • Rhizopus oryzae is the primary cause of mucormycosis, an emerging, life-threatening infection characterized by rapid angioinvasive growth with an overall mortality rate that exceeds 50%. As a representative of the paraphyletic basal group of the fungal kingdom called "zygomycetes," R. oryzae is also used as a model to study fungal evolution. Here we report the genome sequence of R. oryzae strain 99-880, isolated from a fatal case of mucormycosis. The highly repetitive 45.3 Mb genome assembly contains abundant transposable elements (TEs), comprising approximately 20% of the genome. We predicted 13,895 protein-coding genes not overlapping TEs, many of which are paralogous gene pairs. The order and genomic arrangement of the duplicated gene pairs and their common phylogenetic origin provide evidence for an ancestral whole-genome duplication (WGD) event. The WGD resulted in the duplication of nearly all subunits of the protein complexes associated with respiratory electron transport chains, the V-ATPase, and the ubiquitin-proteasome systems. The WGD, together with recent gene duplications, resulted in the expansion of multiple gene families related to cell growth and signal transduction, as well as secreted aspartic protease and subtilase protein families, which are known fungal virulence factors. The duplication of the ergosterol biosynthetic pathway, especially the major azole target, lanosterol 14alpha-demethylase (ERG11), could contribute to the variable responses of R. oryzae to different azole drugs, including voriconazole and posaconazole. Expanded families of cell-wall synthesis enzymes, essential for fungal cell integrity but absent in mammalian hosts, reveal potential targets for novel and R. oryzae-specific diagnostic and therapeutic treatments.
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