| 1. |
- Athanasakis-Kaklamanakis, M., et al.
(författare)
-
Radiative lifetime of the A 2Π1/2 state in RaF with relevance to laser cooling
- 2024
-
Ingår i: PHYSICAL REVIEW A. - 2469-9926 .- 2469-9934. ; 110:1
-
Tidskriftsartikel (refereegranskat)abstract
- The radiative lifetime of the A (2)Pi(1/2) (v = 0) state in radium monofluoride (RaF) is measured to be 35(1) ns. The lifetime of this state and the related decay rate Gamma = 2.86(8) . 86(8) x 107 7 s-1 - 1 are of relevance to the laser cooling of RaF via the optically closed A (2)Pi(1/2) <- X (2)Sigma(1/2) transition, which makes the molecule a promising probe to search for new physics. RaF is found to have a comparable photon-scattering rate to homoelectronic laser-coolable molecules. Owing to its highly diagonal Franck-Condon matrix, it is expected to scatter an order of magnitude more photons than other molecules when using just three cooling lasers, before it decays to a dark state. The lifetime measurement in RaF is benchmarked by measuring the lifetime of the 8P3/2 P 3 / 2 state in Fr to be 83(3) ns, in agreement with literature.
|
|
| 2. |
|
|
| 3. |
- Udrescu, S. M., et al.
(författare)
-
Precision spectroscopy and laser-cooling scheme of a radium-containing molecule
- 2024
-
Ingår i: NATURE PHYSICS. - 1745-2473 .- 1745-2481. ; 20:2, s. 193-194
-
Tidskriftsartikel (refereegranskat)abstract
- Molecules containing heavy radioactive nuclei are predicted to be extremely sensitive to violations of the fundamental symmetries of nature. The nuclear octupole deformation of certain radium isotopes massively boosts the sensitivity of radium monofluoride molecules to symmetry-violating nuclear properties. Moreover, these molecules are predicted to be laser coolable. Here we report measurements of the rovibronic structure of radium monofluoride molecules, which allow the determination of their laser cooling scheme. We demonstrate an improvement in resolution of more than two orders of magnitude compared to the state of the art. Our developments allowed measurements of minuscule amounts of hot molecules, with only a few hundred per second produced in a particular rotational state. The combined precision and sensitivity achieved in this work offer opportunities for studies of radioactive molecules of interest in fundamental physics, chemistry and astrophysics. Measurements of the rovibronic structure of radium monofluoride molecules allow the identification of a laser cooling scheme. This will enable precise tests of fundamental physics, such as searches for parity or time-reversal symmetry violation.
|
|
| 4. |
- Cancelloni, Virginia, et al.
(författare)
-
Reperfusion therapies in patients with acute ischaemic stroke and atrial fibrillation: data on safety and effectiveness from a multi-centre cohort study
- 2024
-
Ingår i: NEUROLOGICAL SCIENCES. - 1590-1874 .- 1590-3478.
-
Tidskriftsartikel (refereegranskat)abstract
- Background Intravenous thrombolysis (IVT) and/or endovascular therapy (EVT) are currently considered best practices in acute stroke patients. Data regarding the efficacy and safety of reperfusion therapies in patients with atrial fibrillation (AF) are conflicting as regards haemorrhagic transformation, mortality, and functional outcome. This study sought to investigate for any differences, in terms of safety and effectiveness, between AF patients with acute ischaemic stroke (AIS) treated and untreated with reperfusion therapies.Methods Data from two multicenter cohort studies (RAF and RAF-NOACs) on consecutive patients with AF and AIS were analyzed to compare patients treated and not treated with reperfusion therapies (IVT and/or EVT). Multivariable logistic regression analysis was performed to identify independent predictors for outcome events: 90-day good functional outcome and mortality. A propensity score matching (PSM) analysis compared treated and untreated patients.Results Overall, 441 (25.4%) were included in the reperfusion-treated group and 1,295 (74.6%) in the untreated group. The multivariable model suggested that reperfusion therapies were significantly associated with good functional outcome. Rates of mortality and disability were higher in patients not treated, especially in the case of higher NIHSS scores. In the PSM comparison, 173/250 patients (69.2%) who had received reperfusion therapies had good functional outcome at 90 days, compared to 146/250 (58.4%) untreated patients (p = 0.009, OR: 1.60, 95% CI:1.11-2.31).Conclusions Patients with AF and AIS treated with reperfusion therapies had a significantly higher rate of good functional outcome and lower rates of mortality compared to those patients with AF and AIS who had undergone conservative treatment.
|
|
