| 1. |
- Almkvist, O, et al.
(författare)
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Mild cognitive impairment -- An early stage of Alzheimer´s disease?
- 1998
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Ingår i: Journal of Neural Transmission. ; 53, s. 21-29
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Tidskriftsartikel (refereegranskat)abstract
- The hypothesis that mild cognitive impairment (MCI) represents an early stage of Alzheimer´s disease (AD) was investigated by reviewing recent research from three sources: asymptomatic and symptomatic individuals carrying mutations that cause AD; hospital
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| 2. |
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| 3. |
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| 4. |
- Bäckman, Lars, et al.
(författare)
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The definition of very old age: A reply to French
- 1999
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Ingår i: American Journal of Psychiatry. ; 156, s. 1291-1292
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Tidskriftsartikel (refereegranskat)abstract
- French (1999) recently commented on the use of the term “very old age” in a previous study by us (Berger, Small, Forsell, Winblad, & Bäckman, 1998). In his comment, French argued that using the label “very old age” in characterizing our study sample was a
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| 5. |
- Wahlin, A, et al.
(författare)
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Influences of thyroid stimulating hormone on cognitive functioning in very old age
- 1998
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Ingår i: Journal of Gerontology: Psychological Sciences. ; 53, s. 234-239
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Tidskriftsartikel (refereegranskat)abstract
- This study investigated the relationship of thyroxine (T4) and thyroid stimulating hormone (TSH) within normal ranges to cognitive performance in very old age. The participants (N = 200) were selected from a population-based study of non-demented persons
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| 6. |
- Wahlin, T B, et al.
(författare)
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Reactions to predictive testing in Huntington disease : case reports of coping with a new genetic status.
- 1997
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Ingår i: American Journal of Medical Genetics. - 0148-7299 .- 1096-8628. ; 73:3, s. 356-65
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Tidskriftsartikel (refereegranskat)abstract
- A predictive testing program for Huntington disease has been available in Stockholm, Sweden since October 1990. Psychosocial assessments were performed throughout the testing program to evaluate the impact of the risk situation itself and the effect of predictive testing, and to identify those individuals who were most vulnerable to severe stress and anxiety reactions. All subjects underwent neurological, neuropsychological, and psychiatric examinations. Individuals undergoing predictive testing were assessed twice by a genetic counsellor before receiving their results, and at 10 days (gene carriers only) and then 2, 6, 12, and 24 months after receiving the results. The process of coping with the test results and the psychological adjustment to knowledge about new genetic status have been shown to vary considerably. In this report, we describe the results obtained from two gene carriers and two noncarriers. The four persons chosen represent different ways of coping with the outcome of the test and of integrating knowledge about their genetic status into everyday life. These cases illustrate common themes and recurrent problems often surfacing during the counselling and testing process. The longitudinal evaluations provide information about the impact, adaptation, and long-term effects of living with a new genetic status.
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| 7. |
- Berger, AK, et al.
(författare)
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The occurrence of depressive symptoms in the preclinical phase of AD - A population-based study
- 1999
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Ingår i: NEUROLOGY. - : LIPPINCOTT WILLIAMS & WILKINS. - 0028-3878. ; 53:9, s. 1998-2002
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To examine preclinical depressive symptoms 3 years before the diagnosis of AD. Methods: The authors compared incident AD patients and nondemented individuals in terms of baseline mood- and motivation-related symptoms of depression, and assesse
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| 8. |
- Bäckman, Lars, et al.
(författare)
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A continuity view of episodic memory impairment: Illustrations from Alzheimer´s disease and major depression
- 1998
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Ingår i: Basic mechanisms in cognition and language. - : New York: Pergamon. ; , s. 243-260
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- There is converging evidence that, in a variety of more or less devastating conditions associated with cognitive impairment (e.g., dementia, amnesia, depression, alcohol intoxication, sleep deprivation), the primary function affected is the ability to acq
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| 9. |
- Bäckman, Lars, et al.
(författare)
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Brain regions associated with episodic retrieval in normal aging and Alzheimer's disease
- 1999
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Ingår i: NEUROLOGY. - : LIPPINCOTT WILLIAMS & WILKINS. - 0028-3878. ; 52:9, s. 1861-1870
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To examine patterns of brain activation during verbal episodic retrieval in normal elderly subjects and patients in an early phase of AD. Background: It is established that 1) a profound episodic memory impairment is a cardinal symptom of AD;
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| 10. |
- Bäckman, Lars, et al.
(författare)
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Cognitive functioning in very old age
- 1999
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Ingår i: Handbook of cognitive aging. - : Mahwah, NJ: Erlbaum. ; , s. 499-558
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The general objective of this chapter is to provide an overview of current research on cognitive functioning among very old adults, with particular emphasis on memory functioning. Of special interest is whether empirical regularities derived from traditi
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