| 1. |
- Lissek, T, et al.
(författare)
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Building Bridges through Science
- 2017
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Ingår i: Neuron. - : Elsevier BV. - 1097-4199 .- 0896-6273. ; 96:4, s. 730-735
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Lin, Yan-Shih, et al.
(författare)
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Optimal stomatal behaviour around the world
- 2015
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Ingår i: Nature Climate Change. - : Springer Science and Business Media LLC. - 1758-678X .- 1758-6798. ; 5, s. 459-464
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Tidskriftsartikel (refereegranskat)abstract
- Stomatal conductance (gs) is a key land-surface attribute as it links transpiration, the dominant component of global land evapotranspiration, and photosynthesis, the driving force of the global carbon cycle. Despite the pivotal role of gs in predictions of global water and carbon cycle changes, a globalscale database and an associated globally applicable model of gs that allow predictions of stomatal behaviour are lacking. Here,we present a database of globally distributed gs obtained in the field for a wide range of plant functional types (PFTs) and biomes. We find that stomatal behaviour differs among PFTs according to their marginal carbon cost of water use, as predicted by the theory underpinning the optimal stomatal model1 and the leaf and wood economics spectrum2,3.We also demonstrate a global relationship with climate. These findings provide a robust theoretical framework for understanding and predicting the behaviour of gs across biomes and across PFTs that can be applied to regional, continental and global-scale modelling of ecosystem productivity, energy balance and ecohydrological processes in a future changing climate.
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| 3. |
- Lin, Yan-Shih, et al.
(författare)
-
Optimal stomatal behaviour around the world
- 2015
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Ingår i: Nature Climate Change. - 1758-6798 .- 1758-678X. ; 5:5, s. 459-464
-
Tidskriftsartikel (refereegranskat)abstract
- Stomatal conductance (g(s)) is a key land-surface attribute as it links transpiration, the dominant component of global land evapotranspiration, and photosynthesis, the driving force of the global carbon cycle. Despite the pivotal role of g(s) in predictions of global water and carbon cycle changes, a global-scale database and an associated globally applicable model of g(s) that allow predictions of stomatal behaviour are lacking. Here, we present a database of globally distributed g(s) obtained in the field for a wide range of plant functional types (PFTs) and biomes. We find that stomatal behaviour differs among PFTs according to their marginal carbon cost of water use, as predicted by the theory underpinning the optimal stomatal model(1) and the leaf and wood economics spectrum(2,3). We also demonstrate a global relationship with climate. These findin g(s) provide a robust theoretical framework for understanding and predicting the behaviour of g(s) across biomes and across PFTs that can be applied to regional, continental and global-scale modelling of ecosystem productivity, energy balance and ecohydrological processes in a future changing climate.
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| 4. |
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| 5. |
- GholamHosseini, Hamid, et al.
(författare)
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Cuffless blood pressure estimation using pulse transit time and photoplethysmogram intensity ratio
- 2018
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Ingår i: Studies in Health Technology and Informatics, vol 249. - : IOS Press. - 9781614998679 ; , s. 77-83
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Konferensbidrag (refereegranskat)abstract
- High blood pressure (BP) is one of the common risk factors for heart disease, stroke, congestive heart failure, and kidney disease. An accurate, continuous and cuffless BP monitoring technique could help clinicians improve the rate of prevention, detection, and treatment of hypertension and related diseases. Pulse transit time (PTT) has attracted interest as an index of BP changes for cuffless BP measurement techniques. Currently, PPT-based BP measurement approaches have improved and are able to relieve the discomfort associated with an inflated cuff such as that used in auscultatory and oscillometric BP measurement techniques. However, PTT can only track the BP variation in high frequency (HF) which limits the true representation of BP changes. This paper presents a continuous and cuffless BP monitoring method based on multiparameter fusion. We used photoplethysmogram (PPG) and a two-lead electrocardiogram (ECG) and employed an algorithm based on PTT and the PPG intensity ratio (PIR) to continuously track BP in both high and low frequencies and estimate systolic and diastolic BP.
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| 6. |
- Tariq, M., et al.
(författare)
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Homozygosity for a missense variant in COMP gene associated with severe pseudoachondroplasia
- 2018
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Ingår i: Clinical Genetics. - : WILEY. - 0009-9163 .- 1399-0004. ; 93:1, s. 182-186
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Tidskriftsartikel (refereegranskat)abstract
- The phenotypic spectrum associated with heterozygous mutations in cartilage oligomeric matrix protein gene (COMP) range from a mild form of multiple epiphyseal dysplasia (MED) to pseudoachondroplasia (PSACH). However, the phenotypic effect from biallelic COMP variants is unclear. We investigated a large consanguineous Pakistani family with a severe form of PSACH in 2 individuals. Another 14 family members presented with a mild PSACH phenotype similar to MED. Using exome sequencing and subsequent segregation analysis, we identified homozygosity for a COMP missense variant [c.1423G>A; p.(D475N)] in the 2 severely affected individuals, whereas family members with the mild PSACH phenotype were heterozygous. Our observations show for the first time that a biallelic COMP variant may be associated with pronounced and widespread skeletal malformations suggesting an additive effect of the 2 mutated alleles.
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