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- Qian, Yan, et al.
(författare)
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Quantification for total demethylation potential of environmental samples utilizing the EGFP reporter gene
- 2016
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Ingår i: Journal of Hazardous Materials. - : Elsevier. - 0304-3894 .- 1873-3336. ; 306, s. 278-285
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Tidskriftsartikel (refereegranskat)abstract
- Abstract The demethylation potential of pollutants is arguably an innate component of their toxicity in environmental samples. A method was developed for determining the total demethylation potential of food samples (TDQ). The demethylation epigenetic toxicity was determined using the Hep G2 cell line transfected with pEGFP-C3 plasmids containing a methylated promoter of the EGFP reporter gene. The total demethylation potential of the sample extracts (the 5-AZA-CdR demethylation toxic equivalency) can be quantified within one week by using a standard curve of the 5-AZA-CdR demethylation agent. To explore the applicability of TDQ for environmental samples, 17 groundwater samples were collected from heavy polluted Kuihe river and the total demethylation potentials of the sample extracts were measured successfully. Meaningful demethylation toxic equivalencies ranging from 0.00050 to 0.01747 μM were found in all groundwater sample extracts. Among 19 kinds of inorganic substance, As and Cd played important roles for individual contribution to the total demethylation epigenetic toxicity. The TDQ assay is reliable and fast for quantifying the DNA demethylation potential of environmental sample extracts, which may improve epigenetic toxicity evaluations for human risk assessment, and the consistent consuming of groundwater alongside the Kuihe river pose unexpected epigenetic health risk to the local residents.
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| 6. |
- Bao, Jinchen, et al.
(författare)
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Bit-Interleaved Coded SCMA With Iterative Multiuser Detection : Multidimensional Constellations Design
- 2018
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Ingår i: IEEE Transactions on Communications. - : IEEE Press. - 0090-6778 .- 1558-0857. ; 66:11, s. 5292-5304
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Tidskriftsartikel (refereegranskat)abstract
- This paper investigates the constellation/codebook design of a promising uplink multiple access technique, sparse code multiple access (SCMA), proposed for the fifth generation mobile networks. The application of bit-interleaved coded modulation with iterative multiuser detection is considered for uplink SCMA over fading channels. Extrinsic information transfer chart is used to aid the analysis and the design of multidimensional constellations, and the design criteria for multidimensional constellations and labelings optimization are thus established. Furthermore, a new and simple approach of multi-stage optimization for the multidimensional constellation design is proposed for SCMA, to improve the bit-error rate performance and alleviate the complexity of turbo multiuser detection. Numerical and simulation results are also provided to demonstrate the performance and verify the efficiency of the proposed scheme, compared with the state of the art.
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| 7. |
- Bao, Jinchen, et al.
(författare)
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Error Performance of Sparse Code Multiple Access Networks with Joint ML Detection
- 2016
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Ingår i: 2016 IEEE 83RD VEHICULAR TECHNOLOGY CONFERENCE (VTC SPRING). - : IEEE. - 9781509016983
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Konferensbidrag (refereegranskat)abstract
- This paper investigates error performance of sparse code multiple access (SCMA) networks with multiple access channels (MAC) and broadcast channels (BC). We give the closedform expression for the pairwise error probability (PEP) of joint maximum likelihood (ML) detection for multiuser signals over additive white Gaussian noise (AWGN) and Rayleigh fading channels with an arbitrary number of users and multidimensional codebooks. An upper bound for the average symbol error rate (SER) is calculated. The bound is tight in both AWGN channel and Rayleigh fading channels for high SNR regions. The analytical bounds are compared with simulations, and the results confirm the effectiveness of the analysis for both AWGN and Rayleigh fading channels.
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| 8. |
- Bao, J., et al.
(författare)
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Joint Multiuser Detection of Multidimensional Constellations over Fading Channels
- 2017
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Ingår i: IEEE Transactions on Communications. - : IEEE Press. - 0090-6778 .- 1558-0857. ; 65:1, s. 161-172
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Tidskriftsartikel (refereegranskat)abstract
- We investigate the error performance of multidimensional constellations in the multiple access and broadcast channels. More specifically, we provide closed-form expressions for the pairwise error probability (PEP) of the joint maximum likelihood detection, for multiuser signaling in the presence of additive white Gaussian noise and Rayleigh fading. Arbitrary numbers of users and multidimensional signal sets are assumed, while the provided formula for the PEP is a function of the dimension-wise distances of the multidimensional constellation. Furthermore, a useful upper bound on the average symbol error probability is also obtained through the union bound. The analysis is applied to the sparse code multiple access systems. The analytical results are validated successfully through simulations, and show their importance in the multidimensional constellation design.
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| 9. |
- Bao, Jinchen, et al.
(författare)
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Performance Analysis of Uplink SCMA With Receiver Diversity and Randomly Deployed Users
- 2018
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Ingår i: IEEE Transactions on Vehicular Technology. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 0018-9545 .- 1939-9359. ; 67:3, s. 2792-2797
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Tidskriftsartikel (refereegranskat)abstract
- This paper considers the performance analysis of sparse code multiple access (SCMA) with receive diversity arrays and randomly deployed users in a cellular uplink scenario. The impact of path loss on the performance of SCMA is characterized, by assuming independent Rayleigh fading and joint maximum likelihood (ML) receivers. A tight upper bound on the probability of symbol detection error is derived, and the achievable diversity and coding gains are investigated. The analytical results are validated by using simulations, and show that a diversity order which is equal to the product of the number of receive antennas and the signal-space diversity can be achieved, and the large-scale path-loss decreases only the coding gain.
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| 10. |
- Bao, J., et al.
(författare)
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Performance analysis of uplink sparse code multiple access with iterative multiuser receiver
- 2017
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Ingår i: 2017 IEEE International Conference on Communications, ICC 2017. - : Institute of Electrical and Electronics Engineers (IEEE). - 9781467389990
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Konferensbidrag (refereegranskat)abstract
- This paper investigates the asymptotic performance of bit-interleaved coded modulation (BICM) with iterative multiuser detection and decoding in uplink sparse code multiple access (SCMA) systems. The extrinsic information transfer (EXIT) characteristics analysis of the joint multiuser detector for SCMA is provided, and shows that the average detection reliability for multiple users converges to the single-user case, if ideal feedback from the decoder is available to the detector. We develop a tight analytical bound on the convolutionally encoded bit-error rate (BER) for independent Rayleigh fadings, based on the single-user bound with arbitrary multidimensional constellations. Moreover, we analyze the achievable coding and diversity gains of the SCMA-BICM system with iterative receiver. Simulations are carried out to verify the effectiveness of the analysis.
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