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Träfflista för sökning "WFRF:(Barter P) srt2:(2005-2009)"

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1.	Barter, PJ, et al. (author) Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel 2006 In: Journal of internal medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 259:3, s. 247-258 Journal article (peer-reviewed)
2.	Kastelein, John J. P., et al. (author) Lipids, apolipoproteins, and their ratios in relation to cardiovascular events with statin treatment 2008 In: Circulation. - 0009-7322 .- 1524-4539. ; 117:23, s. 3002-3009 Journal article (peer-reviewed)abstract Background - Low-density lipoprotein (LDL)cholesterol is the principal target of lipid-lowering therapy, but recent evidence has suggested more appropriate targets. We compared the relationships of on-treatment levels of LDL cholesterol, non-high-density lipoprotein (HDL) cholesterol, and apolipoprotein B, as well as ratios of total/HDL cholesterol, LDL/HDL cholesterol, and apolipoprotein B/A-I, with the occurrence of cardiovascular events in patients receiving statin therapy. Methods and Results - A post hoc analysis was performed that combined data from 2 prospective, randomized clinical trials in which 10 001 ("Treating to New Targets") and 8888 ("Incremental Decrease in End Points through Aggressive Lipid Lowering") patients with established coronary heart disease were assigned to usual-dose or high-dose statin treatment. In models with LDL cholesterol, non-HDL cholesterol and apolipoprotein B were positively associated with cardiovascular outcome, whereas a positive relationship with LDL cholesterol was lost. In a model that contained non-HDL cholesterol and apolipoprotein B, neither was significant owing to collinearity. Total/HDL cholesterol ratio and the apolipoprotein B/A-I ratio in particular were each more closely associated with outcome than any of the individual proatherogenic lipoprotein parameters. Conclusions - In patients receiving statin therapy, on-treatment levels of non-HDL cholesterol and apolipoprotein B were more closely associated with cardiovascular outcome than levels of LDL cholesterol. Inclusion of measurements of the antiatherogenic lipoprotein fraction further strengthened the relationships. These data support the use of non-HDL cholesterol or apolipoprotein B as novel treatment targets for statin therapy. Given the absence of interventions that have been proven to consistently reduce cardiovascular disease risk through raising plasma levels of HDL cholesterol or apolipoprotein A-I, it seems premature to consider the ratio variables as clinically useful.
3.	Nicholls, SJ, et al. (author) Consumption of saturated fat impairs endothelial function and the anti-inflammatory properties of high density lipoproteins 2005 In: CIRCULATION. - 0009-7322. ; 112:17, s. U435-U436 Conference paper (other academic/artistic)
4.	Nicholls, SJ, et al. (author) Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function 2006 In: Journal of the American College of Cardiology. - : Elsevier BV. - 1558-3597 .- 0735-1097. ; 48:4, s. 715-720 Journal article (peer-reviewed)
5.	Patel, S, et al. (author) Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-inflammatory capacity of high density lipoproteins 2009 In: Atherosclerosis. - : Elsevier BV. - 1879-1484 .- 0021-9150. ; 204:2, s. 424-428 Journal article (peer-reviewed)

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Type of publication: journal article (4); conference paper (1)

Type of content: peer-reviewed (4); other academic/artistic (1)

Author/Editor: Barter, PJ (4); Lundman, P (3); Celermajer, DS (3); Nicholls, SJ (3); Sarrafzadegan, N (1); Holme, Ingar (1); show more...; Patel, S. (1); Olsson, Anders (1); Humphries, SE (1); Wang, XS (1); Reddy, KS (1); Frohlich, J (1); Lambert, G (1); Talmud, PJ (1); Walldius, G (1); Jungner, I (1); Kastelein, John J. P ... (1); Harmer, JA (1); Ballantyne, CM (1); Pedersen, Terje R. (1); Carmena, R (1); Cabezas, MC (1); Chapman, MJ (1); Couture, P (1); De Graaf, J (1); Durrington, PN (1); Faergeman, O (1); Furberg, CD (1); Gagne, C (1); Haffner, SM (1); Krauss, RM (1); Kwiterovich, P (1); Marcovina, S (1); Packard, CJ (1); Pearson, TA (1); Rosenson, R (1); Sniderman, AD (1); Stalenhoef, AF (1); Stein, E (1); Tonkin, AM (1); Williams, KMS (1); Deedwania, Prakash (1); Boekholdt, S. Matthi ... (1); Szarek, Michael (1); Stocker, R. (1); Puranik, R (1); Grundy, S (1); Cater, Nilo B. (1); LaRosa, John C (1); Griffiths, K. (1); show less...

University: Karolinska Institutet (4); Linköping University (1)

Language: English (5)

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