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Träfflista för sökning "WFRF:(Bengtsson Nils O.) "

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1.	2019 Journal article (peer-reviewed)
2.	Abe, O, et al. (author) Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials 2005 In: Lancet (London, England). - 1474-547X. ; 366:9503, s. 2087-2106 Journal article (peer-reviewed)
3.	Bengtsson, O., et al. (author) Freeze-drying of raw beef. : 1. Influence of some raw material variables 1968 In: Journal of the Science of Food and Agriculture. ; 19:6, s. 317-321 Journal article (peer-reviewed)
4.	Bengtsson, O., et al. (author) Freeze-drying of raw beef. : 2. Influence of some freezing and dehydration variables. 1968 In: Journal of the Science of Food and Agriculture. ; 19:9, s. 481-485 Journal article (peer-reviewed)
5.	Bengtsson, O., et al. (author) Freeze-drying of raw beef. : 3. Influence of some packaging and storage variables 1968 In: Journal of the Science of Food and Agriculture. ; 19:9, s. 486-491 Journal article (peer-reviewed)
6.	Bengtsson, Nils, et al. (author) Dielectric properties of fruits at 3 GHz as determined by a cavity pertubation technique. : 2. Measurements on food materials 1971 In: Journal of Microwave Power. ; 2:6, s. 107-123 Journal article (peer-reviewed)
7.	Rydén, Lisa, et al. (author) Tumor-specific VEGF-A and VEGFR2 in postmenopausal breast cancer patients with long-term follow-up : Implication of a link between VEGF pathway and tamoxifen response 2005 In: Breast Cancer Research and Treatment. - The Hague : Nijhoff. - 0167-6806 .- 1573-7217. ; 89:2, s. 135-143 Journal article (peer-reviewed)abstract Vascular endothelial growth factor (VEGF-A) is considered a prognostic indicator for clinical outcome in breast cancer. Conflicting results nevertheless exist and there is a need for larger studies including untreated patients in order to clarify the importance of tumor-specific VEGF-A regarding prognosis as well as potential links to predictive treatment information. VEGF-A and its receptor, vascular endothelial growth receptor 2 (VEGFR2), were therefore analyzed by immunohistochemistry in postmenopausal breast cancers enrolled in a clinical trial where patients were randomized to adjuvant tamoxifen treatment (n=124) for 2 years or no treatment (n=127) with a median follow-up of 18 years. The tumors were arranged in a tumor tissue microarray system enabling parallell analysis of the angiogenic factors and hormone receptor status. Tumor-specific expression of VEGFR2 correlated strongly with expression of VEGF-A and progesterone receptor (PR) negativity, whereas VEGF-A was not associated with hormone receptor status. Among patients with estrogen receptor (ER) positive (fraction > 10%) tumors, there was a statistically significant tamoxifen response in VEGF-A negative tumors at both 10-year and 18-year disease-free survival (DFS), contrasting to VEGF-A positive tumors who had no beneficial effect of tamoxifen. A treatment-interaction variable indicated a marked difference in tamoxifen response depending on VEGFA-status in terms of DFS at 10 and 18 years of follow-up, p=0.046 and p=0.039, respectively. VEGFR2 status did not yield significant predicitve information for tamoxifen response in patients with ER fraction > 10%, whereas in patients with ER fraction > 90% both VEGF-A and VEGFR2 status were associated with tamoxifen treatment effect.

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Result 1-7 of 7

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Type of publication: journal article (7)

Type of content: peer-reviewed (7)

Author/Editor: Christiansen, P. (1); Rosso, R (1); Cameron, D. (1); Schumacher, M. (1); Wang, X. (1); Taylor, C. (1); show more...; Steinberg, S (1); Nilsson, J. (1); Kaufman, M (1); Brown, A. (1); Bergh, J (1); Malmström, Per (1); Landberg, Göran (1); Rydén, Lisa (1); Ivanov, V. (1); Wang, Y. (1); Gnant, M. (1); Jonat, W. (1); Thürlimann, B. (1); Kelly, Daniel (1); James, S. (1); Jackson, S. (1); Whelan, T. (1); Bengtsson-Palme, Joh ... (1); Soderberg, M (1); Nilsson, Henrik (1); Hall, E (1); Lee, M (1); Anderson, S (1); Brenner, H (1); Cross, M (1); Hill, C. (1); Kelly, Ryan (1); Li, Ying (1); Morris, P. (1); Costa, A. (1); Collins, R (1); Moore, Matthew D. (1); Martin, P. (1); Yoshida, M. (1); Abe, O (1); Abe, R (1); Enomoto, K (1); Kikuchi, K (1); Koyama, H (1); Masuda, H (1); Nomura, Y (1); Sakai, K (1); Sugimachi, K (1); Tominaga, T (1); show less...

University: RISE (4); Lund University (3); Umeå University (2); Karolinska Institutet (2); University of Gothenburg (1); Uppsala University (1); show more...; Halmstad University (1); Stockholm University (1); Chalmers University of Technology (1); show less...

Language: English (7)

Research subject (UKÄ/SCB): Agricultural Sciences (4); Medical and Health Sciences (3); Natural sciences (1)

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