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| 2. |
- Högberg, Thomas, et al.
(author)
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Hopp om förbättring av överlevnad i ovarialcancer
- 2015
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In: Läkartidningen. - : Läkartidningen Förlag AB. - 0023-7205 .- 1652-7518. ; 112:50, s. 2281-3
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Journal article (peer-reviewed)abstract
- Ovarian cancer is the most common cause of death from a gynecologic cancer. Every year around 700 women contracts ovarian cancer in Sweden. The overall survival is among the highest in Europe, but still long term relative survival is only 46%. It is a long-held myth that ovarian cancer is a disease without symptoms. Almost 90% of women have symptoms, even in the early stages. Symptoms that should arise suspicion of ovarian cancer and initiate diagnostic work-up are continuous abdominal extension, early feeling of satiety, pelvic or abdominal pain, urinary urge and postmenopausal bleeding. Women's awareness of symptoms and willingness to seek medical advice and the organization of the health care system are important factors determining cancer survival. Ovarian cancer is a heterogeneous group of diseases with different tumor traits and prognosis. Personalized medicine and preventive measures recognizing recent knowledge about tumor biology will positively affect survival.
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| 3. |
- Högberg, Thomas, et al.
(author)
-
Hopp om förbättring av överlevnad i ovarialcancer
- 2015
-
In: Läkartidningen. - : Läkartidningen Förlag AB. - 1652-7518 .- 0023-7205. ; 112
-
Journal article (peer-reviewed)abstract
- Ovarian cancer is the most common cause of death from a gynecologic cancer. Every year around 700 women contracts ovarian cancer in Sweden. The overall survival is among the highest in Europe, but still long term relative survival is only 46%. It is a long-held myth that ovarian cancer is a disease without symptoms. Almost 90% of women have symptoms, even in the early stages. Symptoms that should arise suspicion of ovarian cancer and initiate diagnostic work-up are continuous abdominal extension, early feeling of satiety, pelvic or abdominal pain, urinary urge and postmenopausal bleeding. Women's awareness of symptoms and willingness to seek medical advice and the organization of the health care system are important factors determining cancer survival. Ovarian cancer is a heterogeneous group of diseases with different tumor traits and prognosis. Personalized medicine and preventive measures recognizing recent knowledge about tumor biology will positively affect survival.
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| 4. |
- Kalapotharakos, Grigorios, et al.
(author)
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Long term survival in women with borderline ovarian tumors: a population-based survey of borderline ovarian tumors in Sweden 1960-2007.
- 2016
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In: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley. - 1600-0412 .- 0001-6349. ; 95:4, s. 473-479
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Journal article (peer-reviewed)abstract
- Evaluation of incidence and survival of patients with borderline ovarian tumors in Sweden MATERIAL AND METHODS: All women diagnosed with borderline ovarian tumor in the Swedish Cancer Register 1960-2007 (n=6,252) combined with follow-up in the Swedish Death Registry to 1 July 2009 were included. Estimation of age-standardized relative survival rate according to time periods for diagnosis RESULTS: The incidence of borderline ovarian tumors increased during the study period, with a steep increase during the 1980-ies. The age standardized 5 year relative survival including all borderline tumors diagnosed 2000-2007 was 97% (95% confidence interval: 92-99%). In women age 64 or younger 10 year relative survival related to age at diagnosis of borderline tumors ranged from 95 to 98% and were 89% in women 65-74. In a multivariable analysis including age and decade of diagnosis relative survival for every decade increased. The 10-year relative survival in patients with mucinous and serous borderline tumors did not differ significantly (p=0.121).
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| 5. |
- Olsson, Caroline, 1970, et al.
(author)
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Initial experience with introducing national guidelines for CT- and MRI-based delineation of organs at risk in radiotherapy
- 2019
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In: Physics and Imaging in Radiation Oncology. - : Elsevier. - 2405-6316. ; 11, s. 88-91
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Journal article (peer-reviewed)abstract
- A fundamental problem in radiotherapy is the variation of organ at risk (OAR) volumes. Here we present our initial experience in engaging a large Radiation Oncology (RO) community to agree on national guidelines for OAR delineations. Our project builds on associated standardization initiatives and invites professionals from all radiotherapy departments nationwide. Presently, one guideline (rectum) has successfully been agreed on by a majority vote. Reaching out to all relevant parties in a timely manner and motivating funding agencies to support the work represented early challenges. Population-based data and a scalable methodological approach are major strengths of the proposed strategy.
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