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- Bergkvist, Charlotte, et al.
(författare)
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Dietary exposure to polychlorinated biphenyls and risk of myocardial infarction - A population-based prospective cohort study
- 2015
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Ingår i: International Journal of Cardiology. - : ELSEVIER IRELAND LTD. - 0167-5273 .- 1874-1754. ; 183, s. 242-248
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Tidskriftsartikel (refereegranskat)abstract
- Background: Fish consumption may promote cardiovascular health. The role of major food contaminants, such as polychlorinated biphenyls (PCBs) common in fatty fish, is unclear. We assessed the association between dietary PCB exposure and risk of myocardial infarction taking into account the intake of long-chain omega-3 fish fatty acids. Methods: In the prospective population-based Swedish Mammography Cohort, 33,446 middle-aged and elderly women, free from cardiovascular disease, cancer and diabetes at baseline (1997) were followed-up for 12 years. Validated estimates of dietary PCB exposure and intake of fish fatty acids (eicosapentaenoic acid and docosahexaenoic acid; EPA-DHA) were obtained via a food frequency questionnaire at baseline. Results: During follow-up 1386 incident cases of myocardial infarction were ascertained through register-linkage. Women in the highest quartile of dietary PCB exposure (median 286 ng/day) had a multivariable-adjusted RR of myocardial infarction of 1.21 (95% confidence interval [CI], 1.01-1.45) compared to the lowest quartile (median 101 ng/day) before, and 1.58 (95% CI, 1.10-2.25) after adjusting for EPA-DHA. Stratification by low and high EPA-DHA intake, resulted in RRs 2.20 (95% CI, 1.18-4.12) and 1.73 (95% CI, 0.81-3.69), respectively comparing highest PCB tertile with lowest. The intake of dietary EPA-DHA was inversely associated with risk of myocardial infarction after but not before adjusting for dietary PCB. Conclusion: Exposure to PCBs was associated with increased risk of myocardial infarction, while some beneficial effect was associated with increasing EPA and DHA intake. To increase the net benefits of fish consumption, PCB contamination should be reduced to a minimum. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
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| 2. |
- Bergkvist, Charlotte, et al.
(författare)
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Dietary exposure to polychlorinated biphenyls and risk of myocardial infarction in men - A population-based prospective cohort study
- 2016
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Ingår i: Environment International. - : PERGAMON-ELSEVIER SCIENCE LTD. - 0160-4120 .- 1873-6750. ; 88, s. 9-14
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Tidskriftsartikel (refereegranskat)abstract
- Background: Major food contaminants such as polychlorinated biphenyls (PCBs) are proposed to play a role in the etiology of cardiovascular disease (CVD), but to date the impact of PCBs on cardiovascular health need to be explored. Methods and results: We assessed the association between validated food frequency questionnaire-based estimates of dietary PCB exposure and risk of myocardial infarction, ascertained through register-linkage, among 36,759 men from the population-based Swedish Cohort of Men, free of cardiovascular disease, diabetes and cancer at baseline (1997). Relative risks were adjusted for known cardiovascular risk factors, long-chain omega-3 fatty acids (eicosapentaenoic and docosahexaenoic acids) and methyl mercury exposure. During 12 years of follow-up (433,243 person-years), we ascertained 3005 incident cases of myocardial infarction (654 fatal). Compared with the lowest quintile of dietary PCB exposure (median 113 ng/day), men in the highest quintile (median 436 ng/day) had multivariable-adjusted relative risks of 1.74 (95% confidence interval [CI], 1.30-2.33; p-trend < 0.001) for total and 1.97 (95% C11.42-2.75; p-trend < 0.001) for non-fatal myocardial infarction. In mutually adjusted models, dietary PCB exposure was associated with an increased risk of myocardial infarction, while the intake of long-chain omega-3 fish fatty acids was associated with a decreased risk. We also observed an effect modification by adiposity on the association between of dietary PCB exposure and myocardial infarction, with higher risk among lean men (p value for interaction = 0.03). Conclusions: Exposure to PCBs via diet was associated with increased risk of myocardial infarction in men. (C) 2015 Elsevier Ltd. All rights reserved.
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| 5. |
- Bäccman, Charlotte, 1973-, et al.
(författare)
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Welfare technology and user experience : A study of seniors´ expectations on and first impressions of a robotic shower
- 2019
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Ingår i: Proceedings of the 52nd Hawaii International Conference on System Sciences. - Honolulu, Hawaii, USA : University of Hawaii at Manoa. - 9780998133126 ; , s. 4297-4306
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Konferensbidrag (refereegranskat)abstract
- This study shows that seniors strive to become more independent and that acceptance of welfare technology needs to be understood in the specific situation. User experiences from welfare technology, such as the robotic shower, that serve in a very intimate situation, may not be comparable to the results from previous studies of, for example, surveillance technology.The preliminary results in this paper build on both qualitative and quantitative data, and show that seniors are in general positive to replacing the current shower situation with a more autonomous shower situation as provided by the robotic shower. An important aspect for acceptance was the functionality of the robotic shower. Furthermore, this study showed that the understanding of the shower situation in general can be used for improvement of the current shower situation, to prevent learned helplessness.
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| 6. |
- Gustafsson, Ann-Sophie, et al.
(författare)
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Behovsstyrd utveckling av välfärdsteknik med test och utvärdering som en naturlig del av verksamhetens förbättringsarbete
- 2019
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Konferensbidrag (populärvet., debatt m.m.)abstract
- Presentation om hur införandet av en automatiserad duschlösning skapade olika värden för två användargrupper, äldre och vårdpersonal. Där oberoende var en viktig aspekt för både personal och äldre, men där personalens perspektiv var mer tvetydigt och ambivalent då deras arbetsinsatser inte bara förbättrades utan även i vissa aspekter försvårades. De äldre användarnas perspektiv handlade mer om ett ökat oberoende och upplevelsen av att återfå kontrollen i duschsituationen. Här diskuterades också resultatens implikationer samt lärdomar från studien.
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