| 1. |
- Prokopenko, Inga, et al.
(författare)
-
Variants in MTNR1B influence fasting glucose levels
- 2009
-
Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 41:1, s. 77-81
-
Tidskriftsartikel (refereegranskat)abstract
- To identify previously unknown genetic loci associated with fasting glucose concentrations, we examined the leading association signals in ten genome-wide association scans involving a total of 36,610 individuals of European descent. Variants in the gene encoding melatonin receptor 1B (MTNR1B) were consistently associated with fasting glucose across all ten studies. The strongest signal was observed at rs10830963, where each G allele (frequency 0.30 in HapMap CEU) was associated with an increase of 0.07 (95% CI = 0.06-0.08) mmol/l in fasting glucose levels (P = 3.2 x 10(-50)) and reduced beta-cell function as measured by homeostasis model assessment (HOMA-B, P = 1.1 x 10(-15)). The same allele was associated with an increased risk of type 2 diabetes (odds ratio = 1.09 (1.05-1.12), per G allele P = 3.3 x 10(-7)) in a meta-analysis of 13 case-control studies totaling 18,236 cases and 64,453 controls. Our analyses also confirm previous associations of fasting glucose with variants at the G6PC2 (rs560887, P = 1.1 x 10(-57)) and GCK (rs4607517, P = 1.0 x 10(-25)) loci.
|
|
| 2. |
- Mohammadi, Siavoush, M, et al.
(författare)
-
Interactive visualization of new electromagnetic quantities
- 2008
-
Ingår i: SIGRAD 2008. - : Linköping University Electronic press. ; , s. 71-74
-
Konferensbidrag (refereegranskat)abstract
- Recent development in classical electrodynamics has demonstratedthe usefulness of different rotational and topological modes in theelectromagnetic fields (angular momentum, polarization, vorticityetc.). Unfortunately, the visualization tools available to illustratethese electrodynamic quantities have hitherto been inadequate.Therefore we have developed a VTK and Python based interactivevisualization tool, with working name EMVT (ElectroMagnetic VisualizationTool), targeted at visualizing precisely these modes.In the near future, EMVT will be further developed to visualize andcontrol live antenna systems, where electromagnetic field data isinstantly received, calculated, and visualized from an antenna or asystem of antennas. It will then be possible to see how the antennaproperties change through direct user interaction in real time.
|
|
| 3. |
- Stål, Oscar, et al.
(författare)
-
Prospects for Lunar Satellite Detection of Radio Pulses from Ultrahigh Energy Neutrinos Interacting with the Moon
- 2007
-
Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 98:7
-
Tidskriftsartikel (refereegranskat)abstract
- The Moon provides a huge effective detector volume for ultrahigh energy cosmic neutrinos, which generate coherent radio pulses in the lunar surface layer due to the Askaryan effect. We report systematic Monte Carlo simulations which show that radio instruments on board a Moon-orbiting satellite can detect Askaryan pulses from neutrinos with energies above 10^{19} eV, i.e. near and above the interesting GZK limit, at the very low fluxes predicted in different scenarios.
|
|
| 4. |
|
|
| 5. |
|
|
| 6. |
- Rothkaehl, H., et al.
(författare)
-
The COMPASS-2 satellite and the ground-based LOIS vector sensing radar facility as novel tools for ionospheric plasma diagnostics
- 2008
-
Ingår i: Journal of Atmospheric and Solar-Terrestrial Physics. - : Elsevier BV. - 1364-6826 .- 1879-1824. ; 70:6, s. 926-936
-
Tidskriftsartikel (refereegranskat)abstract
- To give a more detailed and complete understanding of physical plasma processes that govern the solar-terrestrial space, and to develop qualitative and quantitative models of the magnetosphere-ionosphere-thermosphere coupling, it is necessary to design and build the next generation of instruments for space diagnostics and monitoring. Novel ground-based wide-area sensor networks, such as the LOFAR Outrigger In Scandinavia (LOIS, LOFAR: Low Frequency Array) radar facility, comprising wide band, and vector-sensing radio receivers with full three-dimensional polarization coverage, and multi-spacecraft plasma diagnostics should help solve outstanding problems of space physics and describe long-term environmental changes. The new digital radio frequency analyzer (RFA) on board the low-orbiting COMPASS-2 satellite was designed to monitor and investigate the ionospheric plasma. properties. This two-point ground-based and topside ionosphere-located space plasma diagnostic can be a useful new tool for monitoring and diagnosing turbulent plasma properties. The RFA on board the COMPASS-2 satellite is the first in a series of experiments which is planned to be launched into the near-Earth environment. The main purpose of this presentation is to describe new advanced diagnostic techniques of the near-Earth space plasma and point out the scientific challenges of the COMPASS-2 and LOIS experiments.
|
|
| 7. |
|
|
