| 1. |
- El-Sayed, Najib M., et al.
(författare)
-
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease.
- 2005
-
Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 309:5733, s. 409-15
-
Tidskriftsartikel (refereegranskat)abstract
- Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 represent allelic pairs. Over 50% of the genome consists of repeated sequences, such as retrotransposons and genes for large families of surface molecules, which include trans-sialidases, mucins, gp63s, and a large novel family (>1300 copies) of mucin-associated surface protein (MASP) genes. Analyses of the T. cruzi, T. brucei, and Leishmania major (Tritryp) genomes imply differences from other eukaryotes in DNA repair and initiation of replication and reflect their unusual mitochondrial DNA. Although the Tritryp lack several classes of signaling molecules, their kinomes contain a large and diverse set of protein kinases and phosphatases; their size and diversity imply previously unknown interactions and regulatory processes, which may be targets for intervention.
|
|
| 2. |
- Kese, K. O., et al.
(författare)
-
Contact residual stress relaxation in soda-lime glass Part II. Aspects relating to strength recovery
- 2006
-
Ingår i: Journal of the European Ceramic Society. - : Elsevier BV. - 0955-2219 .- 1873-619X. ; 26:6, s. 1013-1022
-
Tidskriftsartikel (refereegranskat)abstract
- Strength recovery of Vickers indented soda lime glass was measured and compared after annealing at two temperatures: one below and one above T, The atomic force microscope was used to study the cracks. At 540 degrees C, no changes were observed in crack morphology either below the surface or on the surface relative to the pre-anneal state. At 630 degrees C, both sub-surface and surface crack morphology changes were observed. The trends in strength recovery were compared with residual stress relaxation as measured by a new method of stress estimation based on nanoindentation elastic response. At short hold times at 630 degrees C, and regardless of the length of hold time at 540 degrees C, strength recovery of only similar to 30% was measured while at moderately long hold times at 630 similar to C, strong recovery of fracture strength, similar to 132% was measured. Trends in strength recovery above T. are shown to match those of crack tip radius instead of trends in stress relaxation across the residual stress field.
|
|
| 3. |
- Kese, K. O., et al.
(författare)
-
Effect of ageing on the electrical resistivities of (Ba0.69Pb0.31)Ti-3 PTCR ceramic thermistors
- 2005
-
Ingår i: Ceramics International. - : Elsevier BV. - 0272-8842 .- 1873-3956. ; 31:3, s. 375-378
-
Tidskriftsartikel (refereegranskat)abstract
- The electrical resistivity of (Ba0.69Pb0.31)TiO3 PTCR ceramic thermistors aged at temperatures of 175, 200, 250 and 300 degrees C, respectively, were measured. When the samples were aged at temperatures of 175 and 200 degrees C, room-temperature resistivity decreased at the initial ageing stage, and then increased with the ageing time. The samples displayed a monotonous rise of the room-temperature resistivity when the ageing treatments were performed at 250 and 300 degrees C. PTCR effects showed different characteristics after different ageing treatments. These ageing characteristics were analyzed by considering interior oxidation and reduction reactions.
|
|
| 4. |
- Smuk, O., et al.
(författare)
-
The effect of copper on secondary phase precipitation in duplex stainless steel - a thermodynamic calculations approach
- 2005
-
Ingår i: Zeitschrift für Metallkunde. - : Walter de Gruyter GmbH. - 0044-3093. ; 96:8, s. 918-923
-
Tidskriftsartikel (refereegranskat)abstract
- Thermodynamic calculations with Thermo-Calc software and the steel database TCFE3 was applied to investigate the precipitation behavior of industrial grades of duplex stainless steels with high copper content, 1.6 and 2.3 wt.%, Duplok 27 and DUP 27, respectively. Well-documented super duplex stainless grade SAF 2507 with copper content of 0.20 wt.% was used as the reference steel. The results of the calculations are compared with the experimental results obtained previously for these steels. It is shown that copper decreases the high-temperature limit of precipitation of sigma and chi phases and reduces the equilibrium amount of precipitated chi phase. Copper addition to a duplex stainless steel facilitates precipitation of chromium nitride phase and stabilizes it at elevated temperatures. The ferrite-austenite balance at high temperatures is also affected in these steels by the copper addition.
|
|
| 5. |
- Stattin, P., et al.
(författare)
-
Geographical variation in incidence of prostate cancer in Sweden : Survey from the National Prostate Cancer Register
- 2005
-
Ingår i: Scandinavian Journal of Urology and Nephrology. - : Informa UK Limited. - 0036-5599 .- 1651-2065. ; 39:5, s. 372-379
-
Tidskriftsartikel (refereegranskat)abstract
- Objective. To investigate the geographical variation in prostate cancer incidence in Sweden, in particular the incidences of screening-detected tumours and curative treatment of prostate cancer. Material and methods. Data were retrieved from the National Prostate Cancer Register of Sweden for all cases of prostate cancer diagnosed in the year 2000-01. There were a total of 14376 cases of prostate cancer and the mean total annual age-adjusted incidence was 197/100000 men. There were 3318 cases in tumour category T1c, i.e. non-palpable tumours diagnosed during work-up for an elevated serum level of prostate-specific antigen, 1006 of which (30%) were asymptomatic and detected at a health check-up. Results. The difference between the counties with the lowest and highest age-adjusted incidences per 1OO 000 men of total prostate cancer was almost twofold (128 vs 217). The corresponding variation in incidence of category Tie tumours was more than fourfold (13 vs 60), the difference in incidence of Tie tumours detected in asymptomatic men was up to 10-fold (2 vs 20), and there was more than a fourfold variation in incidence of curative treatment between counties (13 vs 67). Measured incidences were mostly highest in urban regions and in counties with university hospitals. Conclusion. There are large geographical variations in prostate cancer incidence and in the frequency of curative treatment for prostate cancer in Sweden and there appear to be large geographical variations in the uptake of prostate cancer screening. © 2005 Taylor & Francis.
|
|
