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Träfflista för sökning "WFRF:(Bjorklund S) srt2:(1995-1999)"

Search: WFRF:(Bjorklund S) > (1995-1999)

  • Result 1-10 of 19
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1.
  • Ahlroth, S, et al. (author)
  • The output of the Swedish education sector
  • 1997
  • In: REVIEW OF INCOME AND WEALTH. - : INT ASSOC RES INCOME WEALTH. - 0034-6586. ; :1, s. 89-104
  • Journal article (other academic/artistic)abstract
    • The output of the Swedish education sector is defined as the addition to lifetime incomes generated by the schooling system. Using cross-sectional information on wages, employment rates, working hours, school-participation and leisure time, all by years o
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  • Bjorklund, K, et al. (author)
  • Pregnancy-related back and pelvic pain and changes in bone density
  • 1999
  • In: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. - : MUNKSGAARD INT PUBL LTD. - 0001-6349. ; 78:8, s. 681-685
  • Journal article (other academic/artistic)abstract
    • Objective. To elucidate whether there is an association between pregnancy-related back and pelvic pain and changes in bone density. Methods. In this prospective cohort study. bone density was measured in the distal and ultradistal forearm at 12 and 35 wee
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  • Grander, D, et al. (author)
  • Factors influencing the response to interferon therapy in chronic hepatitis C. Studies on viral genotype and induction of 2',5'-oligoadenylate synthetase in the liver and peripheral blood cells
  • 1996
  • In: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 1502-7708 .- 0036-5521. ; 31:6, s. 604-611
  • Journal article (peer-reviewed)abstract
    • BACKGROUND: The mechanism behind the antiviral action of interferon (IFN) therapy in chronic hepatitis C virus (HCV) infection is not well understood, and, furthermore, few factors have been shown to be good predictors of a favourable response to IFN treatment in chronic HCV infection. METHODS: Freshly explanted liver cells and peripheral blood mononuclear cells (PBMC) from 80 patients with chronic HCV infection were used to study the capacity of IFN to induce the enzyme 2',5'-oligoadenylate synthetase (2'5'-AS) in vitro. The HCV genotype was determined in 53 patients. The induction of 2'5'-AS was correlated to the results of IFN-alpha treatment in 36 patients. RESULTS: Normalization of transaminases during IFN treatment was significantly associated with 2'5'-AS levels in liver cells cultured in the absence of IFN. A similar tendency, although not statistically significant, was found for IFN-induced levels of 2'5'-AS in liver cells. No such associations were found when PBMC were analysed. Six patients showed a sustained biochemical response. These six did not deviate significantly from the remaining patients with regard to base-line or IFN-induced levels of 2'5'-AS in liver cells or PBMC. Eradication of HCV RNA during IFN treatment did not correlate with 2'5'-AS levels in liver cells. Comparison of HCV genotype and clinical response showed that patients with genotype 3a had the most favourable outcome. No association was found between liver histology and treatment outcome. CONCLUSION: These data imply that direct effects of IFN on liver cells are of importance for the response to IFN treatment.
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  • Result 1-10 of 19

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