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Sökning: WFRF:(Blakely I) > (2010-2014)

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  • Prasanna, Pataje G. S., et al. (författare)
  • Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop
  • 2010
  • Ingår i: Radiation Research. - 0033-7587 .- 1938-5404. ; 173:2, s. 245-53
  • Tidskriftsartikel (refereegranskat)abstract
    • Radiation exposures from accidents, nuclear detonations or terrorist incidents are unlikely to be homogeneous; however, current biodosimetric approaches are developed and validated primarily in whole-body irradiation models. A workshop was held at the Armed Forces Radiobiology Research Institute in May 2008 to draw attention to the need for partial-body biodosimetry, to discuss current knowledge, and to identify the gaps to be filled. A panel of international experts and the workshop attendees discussed the requirements and concepts for a path forward. This report addresses eight key areas identified by the Workshop Program Committee for future focus: (1) improved cytogenetics, (2) clinical signs and symptoms, (3) cutaneous bioindicators, (4) organ-specific biomarkers, (5) biophysical markers of dose, (6) integrated diagnostic approaches, (7) confounding factors, and (8) requirements for post-event medical follow-up. For each area, the status, advantages and limitations of existing approaches and suggestions for new directions are presented.
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