| 1. |
- F. Abdel-Magied, Ahmed, et al.
(författare)
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Magnetic metal-organic frameworks for efficient removal of cadmium(II), and lead(II) from aqueous solution
- 2022
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Ingår i: Journal of Environmental Chemical Engineering. - : Elsevier BV. - 2213-2929 .- 2213-3437. ; 10:3
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Tidskriftsartikel (refereegranskat)abstract
- Efficient and convenient methods for the removal of toxic heavy metal ions especially Cd(II) and Pb(II) from aqueous solutions is of great importance due to their serious threat to public health and the ecological system. In this study, two magnetic metal-organic frameworks (namely: Fe3O4@ZIF-8, and Fe3O4@UiO-66–NH2) were synthesized, fully characterized, and applied for the adsorption of Cd(II) and Pb(II) from aqueous solutions. The adsorption efficiencies for the prepared nanocomposites are strongly dependent on the pH of the aqueous solution. The maximum adsorption capacities of Fe3O4@UiO-66–NH2, and Fe3O4@ZIF-8 at pH 6.0 were calculated to be 714.3 mg·g−, and 370 mg·g−1 for Cd(II), respectively, and 833.3 mg·g−1, and 666.7 mg·g−1 for Pb(II), respectively. The adsorption process follows a pseudo-second-order model and fit the Langmuir isotherm model. Moreover, the thermodynamic studies revealed that the adsorption process is endothermic, and spontaneous in nature. A plausible adsorption mechanism was discussed in detail. The magnetic adsorbents: Fe3O4@ZIF-8, and Fe3O4@UiO-66–NH2 showed excellent reusability, maintaining the same efficiency for at least four consecutive cycles. These results reveal the potential use of magnetic Fe3O4@ZIF-8, and Fe3O4@UiO-66–NH2 as efficient adsorbents in removing Cd(II) and Pb(II) from aqueous solutions.
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| 2. |
- F. Abenoza, Roberto, et al.
(författare)
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What is the role of weather, built-environment and accessibility geographical characteristics in influencing travelers’ experience?
- 2018
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Ingår i: Transportation Research Part A. - 0965-8564 .- 1879-2375.
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Tidskriftsartikel (refereegranskat)abstract
- We examine the effect of weather, accessibility and built-environment characteristics on overall travel experience as well as the experience with the latest trips. These are factors that are often disregarded in the travel satisfaction literature even though they are believed to largely influence the first mile of the door-to-door trip. This study fills a research gap in investigating all these factors by using, amongst other, a relatively large travel satisfaction survey from years 2009 to 2015 and by focusing on urban and peri-urban geographical contexts, the city and county of Stockholm (Sweden), respectively. The results show that county dwellers living close to a metro station and in well linked-to-all areas report higher overall travel satisfaction evaluations. In addition, precipitation and ground covered with snow have a negative influence on travel satisfaction. Our findings indicate that built-environment characteristics exert a rather weak influence on the travel experience, especially in the peri-urban context. However, some aspects such as living in areas with medium densities, low income and with high safety perceptions around public transport stations are associated with higher satisfaction levels. In turn, areas with single land uses are found to have lower travel satisfactions. These results are important for public transport planners and designers in devising measures to prevent and mitigate the negative outcome of some weather conditions and to conceive better designed transit oriented developments.
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| 3. |
- McKenzie, Robert J., et al.
(författare)
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Typification of the name Arctotis lanata and those of some southern African Haplocarpha species (Asteraceae, Arctotideae)
- 2008
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Ingår i: Taxon. - 0040-0262 .- 1996-8175. ; 57:2, s. 612-614
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Tidskriftsartikel (refereegranskat)abstract
- In a recent floristic treatment, Haplocarpha thunbergii Less. was considered to be the correct name for H. scaposa Harv. The name H. thunbergii is a substitute name for Arctotis lanata Thunb. Examination of the original material in the Thunberg herbarium proved that Thunberg based the name A. lanata on three specimens each belonging to different species (those currently known as A. acaulis L., If. lanata Less. and If. parvifolia (Schltr.) Beauverd). Our identifications of these specimens proved that the names A. lanata and H. scaposa are not conspecific and H. scaposa is not a homotypic synonym of H. thunbergii. Herein a lectotype for H. scoposa is designated from the syntypes specified by Harvey. With the objective of maintaining nomenclatural stability, we lectotypify A. lanata and place it in synonymy of A. acaulis, thus preserving usage of the name H. parvifolia. An updated synonymy for A. acaulis is provided. In addition, lectotypes are designated for A. fosteri N.E. Br., A. oocephala DC., A. parvifolia Schltr., H. lyrata Harv. and H. transvaalensis Gand.
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| 4. |
- Wymeersch, Henk, 1976, et al.
(författare)
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6G Radio Requirements to Support Integrated Communication, Localization, and Sensing
- 2022
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Ingår i: 2022 Joint European Conference on Networks and Communications and 6G Summit, EuCNC/6G Summit 2022. ; , s. 463-469
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Konferensbidrag (refereegranskat)abstract
- 6G will be characterized by extreme use cases, not only for communication, but also for localization, and sensing. The use cases can be directly mapped to requirements in terms of standard key performance indicators (KPIs), such as data rate, latency, or localization accuracy. The goal of this paper is to go one step further and map these standard KPIs to requirements on signals, on hardware architectures, and on deployments. Based on this, system solutions can be identified that can support several use cases simultaneously. Since there are several ways to meet the KPIs, there is no unique solution and preferable configurations will be discussed.
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| 6. |
- Dorlo, Thomas P. C., et al.
(författare)
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Visceral leishmaniasis relapse hazard is linked to reduced miltefosine exposure in patients from Eastern Africa : a population pharmacokinetic/pharmacodynamic study
- 2017
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Ingår i: Journal of Antimicrobial Chemotherapy. - : OXFORD UNIV PRESS. - 0305-7453 .- 1460-2091. ; 72:11, s. 3131-3140
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Tidskriftsartikel (refereegranskat)abstract
- Background: Low efficacy of miltefosine in the treatment of visceral leishmaniasis was recently observed in Eastern Africa. Objectives: To describe the pharmacokinetics and establish a pharmacokinetic/pharmacodynamic relationship for miltefosine in Eastern African patients with visceral leishmaniasis, using a time-to-event approach to model relapse of disease. Methods: Miltefosine plasma concentrations from 95 patients (48 monotherapy versus 47 combination therapy) were included in the population pharmacokinetic model using non-linear mixed effects modelling. Subsequently a time-to-event model was developed to model the time of clinical relapse. Various summary pharmacokinetic parameters (various AUCs, Time > EC50, Time > EC90), normalized within each treatment arm to allow simultaneous analysis, were evaluated as relapse hazard-changing covariates. Results: A two-compartment population model with first-order absorption fitted the miltefosine pharmacokinetic data adequately. Relative bioavailability was reduced (- 74%, relative standard error 4.7%) during the first week of treatment of the monotherapy arm but only the first day of the shorter combination regimen. Time to the relapse of infection could be described using a constant baseline hazard (baseline 1.8 relapses/year, relative standard error 72.7%). Miltefosine Time > EC90 improved the model significantly when added in a maximum effect function on the baseline hazard (half maximal effect with Time. > EC90 6.97 days for monotherapy). Conclusions: Miltefosine drug exposure was found to be decreased in Eastern African patients with visceral leishmaniasis, due to a (transient) initial lower bioavailability. Relapse hazard was inversely linked to miltefosine exposure. Significantly lower miltefosine exposure was observed in children compared with adults, further urging the need for implementation of dose adaptations for children.
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| 7. |
- Dostert, Maria, et al.
(författare)
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Packable hyperbolic surfaces with symmetries
- 2022
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Ingår i: Canadian mathematical bulletin. - : Canadian Mathematical Society. - 0008-4395. ; , s. 1-11
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Tidskriftsartikel (refereegranskat)abstract
- We discuss several ways of packing a hyperbolic surface with circles (of either varying radii or all being congruent) or horocycles, and note down some observations related to their symmetries (or the absence thereof).
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| 8. |
- Zheng, H., et al.
(författare)
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A Cre-driver rat model for anatomical and functional analysis of glucagon (Gcg)-expressing cells in the brain and periphery
- 2022
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Ingår i: Molecular Metabolism. - : Elsevier BV. - 2212-8778. ; 66
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The glucagon gene (Gcg) encodes preproglucagon, which is cleaved to form glucagon-like peptide 1 (GLP1) and other mature signaling molecules implicated in metabolic functions. To date there are no transgenic rat models available for precise manipulation of GLP1-expressing cells in the brain and periphery. Methods: To visualize and manipulate Gcg-expressing cells in rats, CRISPR/Cas9 was used to express iCre under control of the Gcg promoter. Gcg-Cre rats were bred with tdTomato reporter rats to tag Gcg-expressing cells. Cre-dependent AAVs and RNAscope in situ hybridization were used to evaluate the specificity of iCre expression by GLP1 neurons in the caudal nucleus of the solitary tract (cNTS) and intermediate reticular nucleus (IRt), and by intestinal and pancreatic secretory cells. Food intake was assessed in heterozygous (Het) Gcg-Cre rats after chemogenetic stimulation of cNTS GLP1 neurons expressing an excitatory DREADD. Results: While genotype has minimal effect on body weight or composition in chow-fed Gcg-Cre rats, homozygous (Homo) rats have lower plasma glucose levels. In neonatal and adult Gcg-Cre/tdTom rats, reporter-labeled cells are present in the cNTS and IRt, and in additional brain regions (e.g., basolateral amygdala, piriform cortex) that lack detectable Gcg mRNA in adults but display transient developmental or persistently low Gcg expression. Compared to wildtype (WT) rats, hindbrain Gcg mRNA and GLP1 protein in brain and plasma are markedly reduced in Homo Gcg-Cre rats. Chemogenetic stimulation of cNTS GLP1 neurons reduced overnight chow intake in males but not females, the effect in males was blocked by antagonism of central GLP1 receptors, and hypophagia was enhanced when combined with a subthreshold dose of cholecystokinin-8 to stimulate gastrointestinal vagal afferents. Conclusions: Gcg-Cre rats are a novel and valuable experimental tool for analyzing the development, anatomy, and function of Gcg-expressing cells in the brain and periphery. In addition, Homo Gcg-Cre rats are a unique model for assessing the role of Gcg-encoded proteins in glucose homeostasis and energy metabolism.
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