| 1. |
- Birgegard, Andreas, et al.
(författare)
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Longitudinal experiences and impact of the COVID-19 pandemic among people with past or current eating disorders in Sweden
- 2021
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Ingår i: Eating Disorders. - : ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD. - 1064-0266 .- 1532-530X. ; 30:6, s. 602-617
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Tidskriftsartikel (refereegranskat)abstract
- The study aimed to document the impact of the COVID-19 pandemic on the health and well-being of individuals with past and current eating disorders (ED) in Sweden. We re-contacted participants with a known lifetime history of ED from two previous Swedish studies. Participants completed an online survey about health and functioning at baseline early in the pandemic (Wave 1 ca May/June 2020; N= 982) and six months later (Wave 2 Dec/Jan 2020/21; N= 646). Three important patterns emerged: 1) higher current ED symptoms were associated with greater anxiety, worry, and pandemic-related ED symptom increase; 2) patterns were fairly stable across time, although a concerning percentage (23%) who were symptom-free at Wave 1 reported the re-emergence of symptoms at Wave 2; and 3) only a minority of participants (<50%) with a current ED were in treatment, and of those in treatment, many reported fewer treatment sessions and decreased quality of care. The COVID-19 pandemic appears to pose serious health challenges for individuals with an ED, whether currently symptomatic or in remission. We encourage health service providers and patient advocates to be alert to the needs of individuals with ED and to take active measures to ensure access to appropriate evidence-based care both during and following the pandemic.
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| 2. |
- Birgegard, Andreas, et al.
(författare)
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Proposal for increasing diagnostic clarity in research and clinical practice by renaming and reframing atypical anorexia nervosa as "Restrictive Eating Disorder" (RED)
- 2023
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Ingår i: Eating Behaviors. - : ELSEVIER. - 1471-0153 .- 1873-7358. ; 50
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Tidskriftsartikel (refereegranskat)abstract
- Atypical anorexia nervosa (AAN) in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM5), is characterized by meeting all criteria for anorexia nervosa (AN) except for weight being within or above the "normal" range despite significant weight loss. The current definition is plagued by several problems, resulting in widely heterogeneous operationalizations in research and clinical practice. As such, the poorly defined diagnosis of AAN negatively impacts affected individuals and frustrates research attempts to better understand the syndrome. We consider conceptual flaws in the AAN description and contend that the undefined weight range and nature of weight loss renders these two factors functionally inapplicable in research and practice. They also represent a departure from the originally intended use of the AAN category, i.e., arresting a negative weight trajectory likely to result in AN, making the target population, and the application of the label, unclear. We propose revised criteria and a new name, restrictive eating disorder (RED), intended to reduce stigma and encompass a wide but better-defined range of presentations. The RED criteria focus on clinically significant restrictive behavior that disrupts normal living (i.e., impairment), and cognitive symptoms of overevaluation, disturbed experience, and lack of recognition of illness seriousness. We believe that RED may enable more appropriate clinical application, but also inspire coordinated research toward a more valid psychiatric nosology in the eating disorders field.
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| 3. |
- Silverå Ejneby, Malin, et al.
(författare)
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Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Shaker potassium channel
- 2021
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Ingår i: The Journal of General Physiology. - : Rockefeller University Press. - 0022-1295 .- 1540-7748. ; 153:4
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Tidskriftsartikel (refereegranskat)abstract
- Voltage-gated potassium (K-V) channels can be opened by negatively charged resin acids and their derivatives. These resin acids have been proposed to attract the positively charged voltage-sensor helix (S4) toward the extracellular side of the membrane by binding to a pocket located between the lipid-facing extracellular ends of the transmembrane segments S3 and S4. By contrast to this proposed mechanism, neutralization of the top gating charge of the Shaker KV channel increased resin-acid-induced opening, suggesting other mechanisms and sites of action. Here, we explore the binding of two resin-acid derivatives, Wu50 and Wu161, to the activated/open state of the Shaker KV channel by a combination of in silico docking, molecular dynamics simulations, and electrophysiology of mutated channels. We identified three potential resin-acid-binding sites around S4: (1) the S3/S4 site previously suggested, in which positively charged residues introduced at the top of S4 are critical to keep the compound bound, (2) a site in the cleft between S4 and the pore domain (S4/pore site), in which a tryptophan at the top of S6 and the top gating charge of S4 keeps the compound bound, and (3) a site located on the extracellular side of the voltage-sensor domain, in a cleft formed by S1-S4 (the top-VSD site). The multiple binding sites around S4 and the anticipated helical-screw motion of the helix during activation make the effect of resin-acid derivatives on channel function intricate. The propensity of a specific resin acid to activate and open a voltage-gated channel likely depends on its exact binding dynamics and the types of interactions it can form with the protein in a state-specific manner.
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| 4. |
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Slöjdkunnande i förändring : Nordisk slöjdforskning
- 2021
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- Denna nordiska antologi baseras på artiklar från fyra av de nordiska länderna och utgör både en lägesbeskrivning genom tillbakablickar, nutidsskildringar och framtidsperspektiv. Artiklarna har grupperats utifrån fem teman: 1) Slöjdande och slöjdundervisning, 2) Lärarna och slöjdämnet, 3) Eleverna och slöjden, 4) Slöjdkunnande: utmaningar och återupptäckter, samt 5) Slöjd i Norden. Antologin avslutas med en syntetiserande epilog.
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| 5. |
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| 6. |
- Termorshuizen, Jet D., et al.
(författare)
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Longer-term impact of COVID-19 among individuals with self-reported eating disorders in the United States, the Netherlands, and Sweden
- 2023
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Ingår i: International Journal of Eating Disorders. - : WILEY. - 0276-3478 .- 1098-108X. ; 56:1, s. 80-90
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Tidskriftsartikel (refereegranskat)abstract
- Objective We assessed eating disorder (ED) illness status, symptomatology, treatment access, anxiety, and depression in the first year of the COVID-19 pandemic among individuals with a pre-existing ED in the United States (US), the Netherlands (NL), and Sweden (SE). Methods Participants completed online surveys in April-July 2020, at the early stage of the pandemic, and one year later. At one-year follow-up, we added questions addressing retrospective changes in ED symptoms, treatment, and anxiety/depression since the start of the COVID-19 pandemic. We present descriptive statistics and assess change in ED symptomatology, treatment, and anxiety/depression among those with an active or lingering ED. Results Participants (US n = 132; NL n = 219; SE n = 702) were mostly young and female with a history of anorexia nervosa (>60% in all three countries). Across countries, respondents reported impact of COVID-19 on ED symptoms at both time points, with improvement in US and NL at one-year follow-up, and stable but less impact on ED symptoms in SE. Furthermore, at one-year follow-up, roughly half of those in treatment reported reduced treatment access and quality, and the majority of the sample reported increased anxiety and depressive mood since the start of the pandemic. Discussion Our findings suggest that the self-perceived impact of COVID-19 changed over time but remained concerning even one year after the start of the pandemic. Clinicians, community organizations, and policy makers are encouraged to address potentially changing treatment needs in the face of public health emergency events. Public Significance Our findings suggest that the impact of COVID-19 on individuals with eating disorders decreased over time but remained concerning even one year after the start of the pandemic and that the impact differed across countries. Clinicians, community organizations, and policy makers are encouraged to incorporate this knowledge to address potentially changing treatment needs in the face of public health emergency events.
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| 7. |
- Westerlund, Stina, 1968-, et al.
(författare)
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Epilog
- 2021
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Ingår i: Techne series. - : OsloMet - Oslo Metropolitan University. - 1238-9501 .- 1893-1774. ; 28:4, s. vii-x
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Tidskriftsartikel (refereegranskat)abstract
- De olika bidragen i antologin grundar sig i den slöjdverksamhet som funnits i nordiska skolor sedan närmare 150 år. Hur har slöjdkunnandet förändrats? Artiklarna berör många aspekter av slöjdaktiviteter, men skall inte uppfattas som en forskningsöversikt, endast som exempel på nutida slöjdforskning. Här återfinner vi några av alla de eldsjälar som betytt oerhört mycket för slöjdämnets utveckling och konsolidering i både referenslistor och texter. De slöjdande barnens röst blir hörd, ämnets organisation och slöjdlärarnas undervisning diskuteras. Vi påminns även om grundläggande begrepp och bildningsfrågor (no. danning) som utgör en del av basen för all slöjdundervisning oavsett vilken tidsålder vi befinner oss i.
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| 8. |
- Westerlund, Stina, Filosofie doktor, PhD, 1968-, et al.
(författare)
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Epilog
- 2021
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Ingår i: Slöjdkunnande i förändring. - Umeå : NordFo. ; , s. vii-x
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Bokkapitel (refereegranskat)
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| 9. |
- Westerlund, Stina, et al.
(författare)
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Inledning
- 2021
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Ingår i: Techne series. - 1238-9501 .- 1893-1774. ; 28:4, s. ii-vi
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Initiativet till en nordisk antologi har sin grund i att professor Marléne Johansson, Högskolan för design och konsthantverk (HDK), Göteborgs universitet närmade sig den formella pensionsåldern i Sverige. De artiklar som är resultatet i denna antologi representerar författare från olika nordiska länder. Var och har själv fått välja innehåll för sina artiklar, vilket lett till en brokig samling av ämnesval och på så sätt ett rikt men samtidigt vitt förgrenat innehåll, där artiklarna också har olika karaktär. Medan en del är traditionella forskningsartiklar, har andra karaktären av essäer, även nationella traditioner har bidragit till hur artiklarna utformats. Redaktörerna har valt att gruppera artiklarna i fem tematiska avdelningar, där artiklarna, trots olikheterna, ändå karakteriseras av ett övergripande samband, några karaktäriseras av författarna som vetenskapliga essäer. Samtliga artiklar har genomgått dubbelblind granskning av externa granskare. Presentation av respektive författare återfinns i anslutning till artiklarna. Antologin avslutas med en epilog, författad av redaktörerna.
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| 10. |
- Westerlund, Stina, Filosofie doktor, PhD, 1968-, et al.
(författare)
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Inledning
- 2021
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Ingår i: Slöjdkunnande i förändring. - Umeå : NordFo. ; , s. ii-vi
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Bokkapitel (refereegranskat)
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