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Träfflista för sökning "WFRF:(Bozec A) srt2:(2015-2019)"

Sökning: WFRF:(Bozec A) > (2015-2019)

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1.
  • Ferreira, Silvia A, et al. (författare)
  • Bi-directional cell-pericellular matrix interactions direct stem cell fate
  • 2018
  • Ingår i: Nature Communications. - : Nature Publishing Group. - 2041-1723. ; 9:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Modifiable hydrogels have revealed tremendous insight into how physical characteristics of cells' 3D environment drive stem cell lineage specification. However, in native tissues, cells do not passively receive signals from their niche. Instead they actively probe and modify their pericellular space to suit their needs, yet the dynamics of cells' reciprocal interactions with their pericellular environment when encapsulated within hydrogels remains relatively unexplored. Here, we show that human bone marrow stromal cells (hMSC) encapsulated within hyaluronic acid-based hydrogels modify their surroundings by synthesizing, secreting and arranging proteins pericellularly or by degrading the hydrogel. hMSC's interactions with this local environment have a role in regulating hMSC fate, with a secreted proteinaceous pericellular matrix associated with adipogenesis, and degradation with osteogenesis. Our observations suggest that hMSC participate in a bi-directional interplay between the properties of their 3D milieu and their own secreted pericellular matrix, and that this combination of interactions drives fate.
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2.
  • Chang, Tingru, et al. (författare)
  • The role of Sn on the long-term atmospheric corrosion of binary Cu-Sn bronze alloys in architecture
  • 2019
  • Ingår i: Corrosion Science. - : Elsevier Ltd. - 0010-938X .- 1879-0496. ; 149, s. 54-67
  • Tidskriftsartikel (refereegranskat)abstract
    • The role of Sn on the atmospheric corrosion performance of binary Cu-Sn bronze alloys (4–6 wt.% Sn) compared with Cu metal used in outdoor architecture is elucidated in terms of microstructure, native surface oxide composition, patina evolution, corrosion rates, appearance and metal release. Results are presented for non-exposed surfaces and surfaces exposed at different urban and marine sites in Europe up to 5 years and based on multi-analytical findings from microscopic, spectroscopic, electrochemical and chemical investigations. Alloying influenced the corrosion, aesthetic appearance and patina evolution, differently for urban and marine sites, whereas no effects were observed on the release pattern. © 2019 The Authors
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