| 1. |
- Gustavsson, Lars, et al.
(författare)
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Venous lactate levels can be used to identify patients with poor outcome following community-onset norovirus enteritis
- 2012
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Ingår i: Scandinavian Journal of Infectious Diseases. - : Informa UK Limited. - 0036-5548 .- 1651-1980. ; 44:10, s. 782-787
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Tidskriftsartikel (refereegranskat)abstract
- Background: Norovirus enteritis (NVE) can be fatal in frail patients. High blood lactate levels indicate hypoperfusion and predict mortality in many infectious diseases. The objective was to determine the frequency and association with mortality of elevated lactate levels in patients with community-onset NVE. Methods: A retrospective cohort study was performed. All hospitalized adult patients with community-onset NVE verified by polymerase chain reaction during the period August 2008 to June 2009 were included. Vital signs and venous lactate on arrival, co-morbid conditions, and time of death were registered. The outcome measure was 30-day all-cause mortality. Results: Eighty-two patients with a median age of 77 y (interquartile range (IQR) 53-86 y) were included, of whom 47 (57%) were female and 49 (60%) had at least 1 major co-morbid condition. Lactate levels were above the upper limit of normal (ULN; 1.6 mmol/l) in 45 patients (55%). The overall 30-day mortality rate was 7% (6/82). Mortality was 18% (5/28) with lactate >= 2.4 mmol/l (> 50% above the ULN) on admission compared to 2% (1/54) with lactate < 2.4 mmol/l (p < 0.05). Patients who died had a higher median lactate level compared to survivors: 4.5 (IQR 2.7-7.9) mmol/l vs 1.7 (IQR 1.3-2.5) mmol/l, respectively (p < 0.01). The adjusted odds ratio for death within 30 days for a 1 mmol/l increase in lactate was 2.5 (95% confidence interval 1.003-6.3, p = 0.049). Conclusions: We observed a high proportion of patients with elevated lactate levels in community-onset NVE. Lactate elevation could predict mortality. Measurement of blood lactate may be a valuable tool in the clinical management of patients with a suspected norovirus infection.
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| 2. |
- Olsson, Peter, et al.
(författare)
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Minnesteckningar över avlidna ledamöter 2010. Särtryck ur KVVS Årsbok 2011
- 2011
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Ingår i: Kungl. Vetenskaps- och Vitterhets-Samhället i Göteborg (KVVS).
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Minnesteckningar. Kungl. Vetenskaps- och Vitterhets-Samhället - ledamöter avlidna 2010. Bengt Holmberg, Gunilla Åkerström-Hougen, Gunnar Harling, Jan S. Nilsson, Ulf Lagerkvist, Erik Frykman, Sigvard Rubenowitz
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| 3. |
- Verder, Henrik, et al.
(författare)
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Early Surfactant Guided by Lamellar Body Counts on Gastric Aspirate in Very Preterm Infants
- 2013
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Ingår i: Neonatology. - : S. Karger AG. - 1661-7800 .- 1661-7819. ; 104:2, s. 116-122
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Tidskriftsartikel (refereegranskat)abstract
- Background: We have developed a rapid method, based on lamellar body counts (LBC) on gastric aspirate, for identifying newborns who will develop respiratory distress syndrome with a need for surfactant supplementation. Objective: We set out to test whether it was possible to improve the outcome when used in a clinical trial. Methods: We randomly assigned 380 infants born at 24-29 weeks' gestation and supported with nasal continuous positive airway pressure (nCPAP) to receive surfactant guided either by LBC (intervention group) or increasing need for oxygen (control group). The primary outcome was mechanical ventilation or death within 5 days. Secondary outcomes included need for oxygen expressed by arterial to alveolar oxygen tension ratio (a/APO(2)) at the age of 6 h and need for oxygen at day 28. Results: The primary outcomes were equal (25%) in the two groups. The intervention group had higher a/APO(2) than the control group at 6 h, median 0.64 versus 0.52 (p < 0.01), and the subgroup with gestational age 26-29 weeks needed fewer days of oxygen supplementation than the controls, median 2 vs. 9 days (p = 0.01), and fewer infants needed oxygen at day 28 (p = 0.04). Furthermore, there was a tendency in the intervention group towards a shorter duration of nCPAP. Too little or viscose aspirate in 23% of the cases was a limitation of the method. Conclusion: Using LBC test as indicator of lung maturity and early surfactant therapy in very preterm newborns, it is possible to reduce the need for oxygen supplementation. Copyright (C) 2013 S. Karger AG, Basel
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| 4. |
- Alsén, Pia, 1956-, et al.
(författare)
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Fatigue after myocardial infarction : Relationships with indices of emotional distress, and sociodemographic and clinical variables
- 2010
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Ingår i: International Journal of Nursing Practice. - 1322-7114 .- 1440-172X. ; 16:4, s. 326-334
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Tidskriftsartikel (refereegranskat)abstract
- Fatigue and depressive symptoms are relatively common among patients recovering from myocardial infarction (MI). The symptoms of depression and fatigue overlap. The present study aimed at identifying patient fatigue and at examining the incidence of fatigue, particularly without coexisting depression, after MI. The sample comprised 204 consecutive patients who had completed the questionnaires Hospital Anxiety and Depression Scale and the Multidimensional Fatigue Inventory–20 after MI (1 week and 4 months). The results showed that fatigue had decreased after 4 months compared with the time of MI onset. Compared with the general population, patients reported significantly higher levels of fatigue. Furthermore, fatigue was associated with depression, but 33% of the sample reported fatigue without coexisting depression after 4 months. In order to prevent or treat patients' symptoms of fatigue after MI, the concepts of fatigue and depression should be assessed separately so as to exclude overlapping effects.
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| 5. |
- Alsén, Pia, 1956, et al.
(författare)
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Illness perceptions after myocardial infarction: relations to fatigue, emotional distress, and health-related quality of life.
- 2010
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Ingår i: Journal of Cardiovascular Nursing. - 1550-5049. ; 25:2
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Tidskriftsartikel (refereegranskat)abstract
- Background and Research Objective: Health-related quality of life (HRQoL) is impaired in patients after a myocardial infarction (MI), and fatigue and depression are common health complaints among these patients. Patients' own beliefs about their illness (illness perceptions) influence health behavior and health outcomes. The aim of the present study was to examine illness perception and its association with self-reported HRQoL, fatigue, and emotional distress among patients with MI. Subjects and Methods: The sample consisted of 204 patients who had had MI and who completed the questionnaires during the first week in the hospital and 4 months after the MI. The questionnaires used were the Illness Perception Questionnaire, Multidimensional Fatigue Inventory, Hospital Anxiety and Depression Scale, and the Short Form Health Survey (SF-36). Results: Patient's illness perception changed over time from a more acute to a more chronic perception of illness, and beliefs in personal and treatment control of MI had decreased. Furthermore, these negative beliefs were associated with worse experiences of fatigue and lowered HRQoL. Conclusions: Patients' illness perceptions influence health outcomes after an MI. Supporting MI patients in increasing their perception of personal control could be a primary nursing strategy in rehabilitation programs aimed at facilitating health behavior, decreasing experiences of fatigue, and increasing HRQoL.
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| 6. |
- Antoniadis, I., et al.
(författare)
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Extensions of the Poincare group
- 2011
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Ingår i: Journal of Mathematical Physics. - : AIP Publishing. - 1089-7658 .- 0022-2488. ; 52:7
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Tidskriftsartikel (refereegranskat)abstract
- We construct an extension of the Poincare group which involves a mixture of internal and space-time supersymmetries. The resulting group is an extension of the superPoincare group with infinitely many generators which carry internal and space-time indices. It is a closed algebra since all Jacobi identities are satisfied and it has, therefore, explicit matrix representations. We investigate the massless case and construct the irreducible representations of the extended symmetry. They are divided into two sets, longitudinal and transversal representations. The transversal representations involve an infinite series of integer and half-integer helicities. Finally, we suggest an extension of the conformal group along the same line.
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| 7. |
- Belyaev, D., et al.
(författare)
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The BLG theory in light-cone superspace
- 2010
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Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2010:4
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Tidskriftsartikel (refereegranskat)abstract
- The light-cone superspace version of the d = 3, N = 8 superconformal theory of Bagger, Lambert and Gustavsson (BLG) is obtained as a solution to constraints imposed by OSp(2, 2 vertical bar 8) superalgebra. The Hamiltonian of the theory is shown to be a quadratic form of the dynamical supersymmetry transformation.
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| 8. |
- Bengtsson, Anders, et al.
(författare)
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Counterterms in Gravity in the Light-Front Formulation and a D=2 Conformal-like Summetry in Gravity
- 2013
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Ingår i: Journal of High Energy Physics (JHEP). - 1126-6708 .- 1029-8479. ; 2013:3
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- In this paper we discuss gravity in the light-front formulation (light-cone gauge) and show how possible counterterms arise. We find that Poincare invariance is not enough to find the three-point counterterms uniquely. Higher-spin fields can intrude and mimic three-point higher derivative gravity terms. To select the correct term we have to use the remaining reparametrization invariance that exists after the gauge choice. We finally sketch how the corresponding programme for N=8 Supergravity should work.
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| 9. |
- Bengtsson, Anders, 1988, et al.
(författare)
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Counterterms in gravity in the light-front formulation and a D=2 conformal-like symmetry in gravity
- 2013
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Ingår i: Journal of High Energy Physics. - : Springer Science and Business Media LLC. - 1029-8479 .- 1126-6708. ; 58:5-6, s. 485-501
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Tidskriftsartikel (refereegranskat)abstract
- In this paper we discuss gravity in the light-front formulation (light-cone gauge) and show how possible counterterms arise. We find that Poincare invariance is not enough to find the three-point counterterms uniquely. Higher-spin fields can intrude and mimic three-point higher derivative gravity terms. To select the correct term we have to use the remaining reparametrization invariance that exists after the gauge choice. We finally sketch how the corresponding programme for N = 8 Supergravity should work.
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| 10. |
- Brink, Lars, 1943
(författare)
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Counterterms in Gravity in the Light-Front Formulation and a D = 2 Conformal-like Symmetry in Gravity
- 2012
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Ingår i: 7th Mathematical Physics Meeting: Summer School and Conference on Modern Mathematical Physics 2012, MPHYS 2012; Belgrade; Serbia; 9 September 2012 through 19 September 2012. ; , s. 67-84
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Konferensbidrag (refereegranskat)abstract
- In this lecture I discuss gravity in the light-front formulation (light-cone gauge) and show how possible counterterms arise. We find that Poincaré invariance is not enough to find the three-point counterterms uniquely. Higher-spin fields can intrude and mimic three-point higher derivative gravity terms. To select the correct term we have to use the remaining reparametrization invariance that exists after the gauge choice. We finally sketch how the corresponding programme for N = 8 Supergravity should work.
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