| 1. |
- Ananth, Sudarshan, et al.
(författare)
-
BMS algebra from residual gauge invariance in light-cone gravity
- 2021
-
Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2021:11
-
Tidskriftsartikel (refereegranskat)abstract
- We analyze the residual gauge freedom in gravity, in four dimensions, in the light-cone gauge, in a formulation where unphysical fields are integrated out. By checking the invariance of the light-cone Hamiltonian, we obtain a set of residual gauge transformations, which satisfy the BMS algebra realized on the two physical fields in the theory. Hence, the BMS algebra appears as a consequence of residual gauge invariance in the bulk and not just at the asymptotic boundary. We highlight the key features of the light-cone BMS algebra and discuss its connection with the quadratic form structure of the Hamiltonian.
|
|
| 2. |
- Ananth, S., et al.
(författare)
-
Bondi-Metzner-Sachs algebra as an extension of the Poincaré symmetry in light-cone gravity
- 2021
-
Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2021:7
-
Tidskriftsartikel (refereegranskat)abstract
- We analyze possible local extensions of the Poincaré symmetry in light-cone gravity in four dimensions. We use a formalism where we represent the algebra on the two physical degrees of freedom, one with helicity 2 and the other with helicity −2. The representation is non-linearly realized and one of the light-cone momenta is the Hamiltonian, which is hence a non-linear generator of the algebra. We find that this can be locally realized and the Poincaré algebra extended to the BMS symmetry without any reference to asymptotic limits.
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
- Brink, Lars, 1943, et al.
(författare)
-
Looking Beyond the Frontiers of Science : Dedicated to the 80th Birthday of K.K. Phua
- 2022
-
Bok (övrigt vetenskapligt/konstnärligt)abstract
- Professor Kok Khoo Phua is the Founding Director and Emeritus Professor of the Institute of Advanced Studies (IAS) at Nanyang Technological University (NTU) and Adjunct Professor of Department of Physics both at Nanyang Technological University (NTU) and National University of Singapore (NUS). He is the Chairman and Editor-in-Chief of World Scientific Publishing Co Pte Ltd. When he was elected a Fellow of the American Physical Society (APS) in 2009, the citation read: “For tireless efforts to strengthen scientific research throughout Asia and promote international physics education and scholarly exchanges, and for enriching science and education through the World Scientific Publishing Co. he founded.” This unique volume on the occasion of his 80th birthday is a compilation of tributes from his friends who have known him for decades along with scientific articles that celebrate his visionary approach to promote science worldwide.
|
|
| 6. |
- Brink, Lars, 1943, et al.
(författare)
-
Preface
- 2022
-
Ingår i: Looking Beyond the Frontiers of Science: Dedicated to the 80th Birthday of K.K. Phua. - : WORLD SCIENTIFIC. ; , s. v-vi
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)
|
|
| 7. |
- Brink, Mikael, et al.
(författare)
-
Anti-citrullinated protein antibody specificities and pulmonary fibrosis in relation to genetic loci in early rheumatoid arthritis
- 2022
-
Ingår i: Rheumatology. - : Oxford University Press. - 1462-0324 .- 1462-0332. ; 61:12, s. 4985-4990
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives Pulmonary manifestations in RA are common comorbidities, but the underlying mechanisms are largely unknown. The added value of a multiplex of ACPA and genetic risk markers was evaluated for the development of pulmonary fibrosis (PF) in an inception cohort. Methods A total of 1184 patients with early RA were consecutively included and followed prospectively from the index date until death or 31 December 2016. The presence of 21 ACPA fine specificities was analysed using a custom-made microarray chip (Thermo Fisher Scientific, Uppsala, Sweden). Three SNPs, previously found related to PF were evaluated, rs2609255 (FAM13A), rs111521887 (TOLLIP) and rs35705950 (MUC5B). ACPA and genetic data were available for 841 RA patients, of whom 50 developed radiologically defined PF. Results In unadjusted analyses, 11 ACPA specificities were associated with PF development. In multiple variable analyses, six ACPA specificities were associated with increased risk of PF: vimentin (Vim)60-75, fibrinogen (Fib)beta 62-78 (72), Fib alpha 621-635, Bla26, collagen (C)II359-369 and F4-CIT-R (P < 0.01 to P < 0.05). The number of ACPA specificities was also related to PF development (P < 0.05 crude and adjusted models). In multiple variable models respectively adjusted for each of the SNPs, the number of ACPA specificities (P < 0.05 in all models), anti-Vim60-75 (P < 0.05, in all models), anti-Fib beta 62-78 (72) (P < 0.001 to P < 0.05), anti-CII359-369 (P < 0.05 in all models) and anti-F4-CIT-R AQ4 (P < 0.01 to P < 0.05), anti-Fib alpha 621-635 (P < 0.05 in one) and anti-Bla26 (P < 0.05 in two) were significantly associated with PF development. Conclusion The development of PF in an inception cohort of RA patients was associated with both presence of certain ACPA and the number of ACPA specificities and risk genes.
|
|
| 8. |
- Sourander, Birger, et al.
(författare)
-
No effect of remdesivir or betamethasone on upper respiratory tract SARS-CoV-2 RNA kinetics in hospitalised COVID-19 patients: a retrospective observational study
- 2022
-
Ingår i: Infectious Diseases. - : Informa UK Limited. - 2374-4235 .- 2374-4243. ; 54:10, s. 703-712
-
Tidskriftsartikel (refereegranskat)abstract
- Background The viral kinetics of SARS-CoV-2 has been considered clinically important. While remdesivir and corticosteroids are recommended for COVID-19 patients requiring oxygen support, there is a limited number of published reports on viral kinetics in hospitalised patients with COVID-19 treated with remdesivir or corticosteroids. Methods We conducted a retrospective study by collecting longitudinal samples from the nasopharynx/throat of 123 hospitalised patients (median age 55 years, 74% male) with COVID-19, to evaluate the effects of remdesivir and corticosteroid treatment on viral RNA levels. The subjects were divided into four groups: those receiving remdesivir (n = 25), betamethasone (n = 41), both (n = 15), or neither (n = 42). Time to viral RNA clearance was analysed using Kaplan-Meier plots, categorical data were analysed using Fisher's exact test, and Kruskal-Wallis for continuous data. Viral RNA decline rate was analysed using a mixed effect model. Results We found no significant difference in SARS-CoV-2 RNA decline rate or time to SARS-CoV-2 RNA clearance between the groups. Moreover, clinical status at baseline was not correlated with time to viral clearance. Conclusions Since SARS-CoV-2 RNA kinetics was not affected by treatment, repeated sampling from the upper respiratory tract cannot be used to evaluate treatment response.
|
|
| 9. |
|
|
