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Träfflista för sökning "WFRF:(Brown Martin) srt2:(1995-1999)"

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Numrering	Referens	Omslagsbild	Hitta
1.	ABE, O, et al. (författare) EFFECTS OF RADIOTHERAPY AND SURGERY IN EARLY BREAST-CANCER - AN OVERVIEW OF THE RANDOMIZED TRIALS 1995 Ingår i: NEW ENGLAND JOURNAL OF MEDICINE. - 0028-4793. ; 333:22, s. 1444-1455 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
2.	Budka, H, et al. (författare) The human prion diseases: from neuropathology to pathobiology and molecular genetics. Final report of an EU concerted action 1997 Ingår i: Neuropathology and applied neurobiology. - 0305-1846. ; 23, s. 416- Tidskriftsartikel (refereegranskat)
3.	Clarke, M, et al. (författare) Ovarian ablation in early breast cancer: overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group 1996 Ingår i: Lancet (London, England). - 0140-6736. ; 348:9036, s. 1189-1196 Tidskriftsartikel (refereegranskat)
4.	Shah, K, et al. (författare) SV40 as a putative human commensal - Opening remarks - Panel-audience discussion II 1998 Ingår i: SIMIAN VIRUS 40 (SV40): POSSIBLE HUMAN POLYOMAVIRUS. - 1424-6074. ; 94, s. 251-269 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
5.	VETHAMUTHU, Martin S, et al. (författare) AGGREGATE STRUCTURE, GELLING, AND COACERVATION WITHIN THE L(1) PHASE OF THE QUASI-TERNARY SYSTEM ALKYLTRIMETHYLAMMONIUM BROMIDE SODIUM DEOXYCHOLATE WATER 1995 Ingår i: JOURNAL OF COLLOID AND INTERFACE SCIENCE. - : ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS. - 0021-9797. ; 174:2, s. 461-479 Tidskriftsartikel (refereegranskat)abstract The phase behavior of mixtures of a cationic surfactant, cetyltrimethylammonium bromide (CTAB), with a bile salt, sodium desoxycholate (NaDOC), in water has been studied at 25 degrees C. Mixing of the two surfactants at equimolar composition gave an assoc
6.	Webb, Dominic-Luc, et al. (författare) Insulin exocytosis and glucose-mediated increase in cytoplasmic free Ca2+ concentration in the pancreatic beta-cell are independent of cyclic ADP-ribose 1996 Ingår i: Journal of Biological Chemistry. - : Elsevier BV. - 0021-9258 .- 1083-351X. ; 271:32, s. 19074-19079 Tidskriftsartikel (refereegranskat)abstract Stimulation of pancreatic beta-cells by glucose gives rise to an increase in the cytoplasmic free calcium concentration ([Ca2+]i) and exocytosis of insulin. Cyclic adenosine 5'-diphosphate ribose (cADPR), a metabolite of beta-NAD+, has been reported to increase [Ca2+]i in pancreatic beta-cells by releasing Ca2+ from inositol 1,4,5-trisphosphate-insensitive intracellular stores. In the present study, we have examined the role of cADPR in glucose-mediated increases in [Ca2+]i and insulin exocytosis. Dispersed ob/ob mouse beta-cell aggregates were either pressure microinjected with fura-2 salt or loaded with fura-2 acetoxymethyl ester, and [Ca2+]i was monitored by microfluorimetry. Microinjection of beta-NAD+ into fura-2-loaded beta-cells did not increase [Ca2+]i nor did it alter the cells' subsequent [Ca2+]i response to glucose. Cells microinjected with the cADPR antagonist 8NH2-cADPR increased [Ca2+]i in response to glucose equally well as those injected with cADPR. Finally, the ability of cADPR to promote exocytosis of insulin in electropermeabilized beta-cells was investigated. cADPR on its own did not increase insulin secretion nor did it potentiate Ca2+-induced insulin secretion. We conclude that cADPR neither plays a significant role in glucose-mediated increases in [Ca2+]i nor interacts directly with the molecular mechanisms regulating exocytosis of insulin in normal pancreatic beta-cells.

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Resultat 1-6 av 6

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Typ av publikation: tidskriftsartikel (6)

Typ av innehåll: refereegranskat (4); övrigt vetenskapligt/konstnärligt (2)

Författare/redaktör: Schumacher, M. (2); Brown, A. (2); Simon, R. (2); Jonat, W. (2); James, S. (2); Jackson, S. (2); visa fler...; Soderberg, M (2); Cross, M (2); Hill, C. (2); Collins, R (2); Nakamura, Y. (2); Martin, P. (2); Yoshida, M. (2); Abe, O (2); Abe, R (2); Enomoto, K (2); Kikuchi, K (2); Koyama, H (2); Nomura, Y (2); Uchino, J (2); Haybittle, JL (2); Davies, C (2); Harvey, VJ (2); Holdaway, TM (2); Kay, RG (2); Mason, BH (2); Forbes, JF (2); Jakesz, R (2); Yosef, HMA (2); Focan, C (2); Lobelle, JP (2); Peek, U (2); Oates, GD (2); Powell, J (2); Ragaz, J (2); Cirrincione, C (2); Norton, L (2); Weiss, RB (2); Baum, M (2); Cuzick, J (2); Houghton, J (2); Riley, D (2); Gordon, NH (2); Davis, HL (2); Naja, A (2); Dubois, JB (2); Delozier, T (2); Rambert, P (2); Andrysek, O (2); Barkmanova, J (2); visa färre...

Lärosäte: Karolinska Institutet (5); Uppsala universitet (3)

Språk: Engelska (6)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (1)

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