| 1. |
- Gale, S. J., et al.
(författare)
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Band termination spectroscopy in 157Er
- 1995
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Ingår i: Journal of Physics G: Nuclear and Particle Physics. - 0954-3899. ; 21:2, s. 193-213
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Tidskriftsartikel (refereegranskat)abstract
- The level scheme of 157Er has been extended from a spin region where the nucleus behaves as a prolate rotor to a region where the spin is produced by the alignment of all or most of the available valence nucleons along the symmetry axis of a weakly deformed oblate shape. The level scheme was established at high spin using up to four-fold gamma -ray coincidences detected in the Eurogam spectrometer following the reaction 114Cd( 48Ca,5n)157Er at a bombarding energy of 210 MeV. Particularly favoured states have been established at IK=69/2+, 81/2+, 71/2+, 77/2-, 87-/2 and 89-/2. Specific single-particle configurations are assigned to these special states by comparison with cranked Nilsson-Strutinsky calculations. These states are related to structures observed in the neighbouring nuclei 158Er and 157Ho. These data provide the spectrum of single-particle states for the lowest lying valence orbitals above the 146Gd closed core.
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| 2. |
- Bruce, SPO, et al.
(författare)
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Design and realization of a millimeter-wave Si/SiGe HBT frequency multiplier
- 1998
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Ingår i: IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 0018-9480. ; 46:5, s. 695-700
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, the design of an active millimeterwave frequency doubler using an Si/SiGe heterojunction bipolar transistor (HBT) as the active device is studied. Simulations are made using a developed physics-based large-signal model for Si/SiGe HBT's, wh
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| 3. |
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| 4. |
- Bruce, S, et al.
(författare)
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Extraction of thermal time constant in HBTs using small signal measurements
- 1997
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Ingår i: ELECTRONICS LETTERS. - : IEE-INST ELEC ENG. - 0013-5194. ; 33:2, s. 165-167
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Tidskriftsartikel (refereegranskat)abstract
- A novel method for finding the thermal time constant of HBTs is proposed. It utilises small signal measurements in the frequency domain of the typical negative differential resistance found int he active region, i.e. normal bias conditions for the device.
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| 5. |
- Holmberg, L, et al.
(författare)
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A search for recall bias in a case-control study of diet and breast cancer
- 1996
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Ingår i: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. - : OXFORD UNIV PRESS UNITED KINGDOM. - 0300-5771. ; 25:2, s. 235-244
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Tidskriftsartikel (refereegranskat)abstract
- Background. In retrospective studies of dietary habits and breast cancer risk, recall bias is a concern since diet has been publicized as a cause of breast cancer. Methods, In a case-control study of diet and breast cancer risk nested within a cohort of w
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| 6. |
- Warrier, Indira, et al.
(författare)
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Factor IX inhibitors and anaphylaxis in hemophilia B
- 1997
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Ingår i: Journal of Pediatric Hematology/Oncology. - : Ovid Technologies (Wolters Kluwer Health). - 1077-4114 .- 0192-8562. ; 19:1, s. 23-27
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: We present clinical and laboratory data on 18 children from 12 hemophilia treatment centers in the United States, Canada, and Europe with the purpose of disseminating information regarding a recently recognized, potentially life-threatening complication of treatment in very young children with hemophilia B. Patients and Methods: Twelve hemophilia centers from the United States, Canada, and Europe provided clinical information and laboratory data concerning 18 children who had severe allergic reactions to infused factor (F) IX in close association with the development of an inhibitor to FIX. Laboratory testing for establishment of the diagnosis of hemophilia B and inhibitor to FIX was done locally at the centers treating these patients. FIX gene analysis was performed at one of six molecular genetics institutes. Results: All 18 children had severe hemophilia B, and in each an inhibitor antibody to FIX developed. The median age at the time of anaphylaxis (or anaphylactoid reaction) was 16 months, and the median number of exposure days to FIX was 11. The FIX inhibitor was detected almost simultaneously with the first occurrence of anaphylaxis in 12 of 18 patients. Maximum inhibitor liters were 4.5-600 Bethesda units (BU), with a median titer of 48 BU. FIX gene analysis, performed in 17 of 18 patients, demonstrated complete deletion of the FIX gene in 10 and major derangements in seven. Immune tolerance induction (ITI) regimens have been attempted in 12 patients, with generally poor responses. Two of the 12 experienced nephrotic syndrome while on ITI. Recombinant FVIIa has been successfully used to treat bleeding episodes in 11 of these children. Conclusion: Physicians treating young children with hemophilia B should be aware of the potentially life- threatening complication of anaphylaxis. Children with complete gene deletions or major derangements of the FIX gene appear to be at greater risk. Those identified by genotype as being at greater risk may need to receive their first 10-20 treatments in a medical facility equipped for handling such emergencies. Recombinant FVIIa, although not licensed for use in the United States, appears to be the most suitable treatment option for bleeding episodes in such patients.
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