| 1. |
- Davis, V. T., et al.
(författare)
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Photo-double detachment from the F- ion
- 2005
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Ingår i: Journal of Physics B-Atomic Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 38:14, s. 2579-2589
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Tidskriftsartikel (refereegranskat)
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| 2. |
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| 3. |
- Covington, A. M., et al.
(författare)
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Inner-shell photodetachment from the K- ion
- 2007
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Ingår i: Journal of Physics B-Atomic Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 40:5, s. 935-942
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Nordborg, M, et al.
(författare)
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The pattern of polymorphism in Arabidopsis thaliana
- 2005
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Ingår i: PLoS Biology. - : Public Library of Science (PLoS). - 1545-7885. ; 3:7, s. 1289-1299
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Tidskriftsartikel (refereegranskat)abstract
- We resequenced 876 short fragments in a sample of 96 individuals of Arabidopsis thaliana that included stock center accessions as well as a hierarchical sample from natural populations. Although A. thaliana is a selfing weed, the pattern of polymorphism in general agrees with what is expected for a widely distributed, sexually reproducing species. Linkage disequilibrium decays rapidly, within 50 kb. Variation is shared worldwide, although population structure and isolation by distance are evident. The data fail to fit standard neutral models in several ways. There is a genome-wide excess of rare alleles, at least partially due to selection. There is too much variation between genomic regions in the level of polymorphism. The local level of polymorphism is negatively correlated with gene density and positively correlated with segmental duplications. Because the data do not fit theoretical null distributions, attempts to infer natural selection from polymorphism data will require genome-wide surveys of polymorphism in order to identify anomalous regions. Despite this, our data support the utility of A. thaliana as a model for evolutionary functional genomics.
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| 5. |
- Burns, A, et al.
(författare)
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The clinical use of memantine.
- 2005
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Ingår i: Research and Practice in Alzheimer's Disease. ; 10, s. 205-20
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Tidskriftsartikel (refereegranskat)
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| 6. |
- Gabriel, J. P., et al.
(författare)
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Locomotor pattern in the adult zebrafish spinal cord in vitro
- 2008
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Ingår i: Journal of Neurophysiology. - : American Physiological Society. - 0022-3077 .- 1522-1598. ; 99:1, s. 37-48
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Tidskriftsartikel (refereegranskat)abstract
- The zebrafish is an attractive model system for studying the function of the spinal locomotor network by combining electrophysiological, imaging, and genetic approaches. Thus far, most studies have been focusing on embryonic and larval stages. In this study we have developed an in vitro preparation of the isolated spinal cord from adult zebrafish in which locomotor activity can be induced while the activity of single neurons can be monitored using whole cell recording techniques. Application of NMDA elicited rhythmic locomotor activity that was monitored by recording from muscles or ventral roots in semi-intact or isolated spinal cord preparations, respectively. This rhythmic activity displayed a left-right alternation and a rostrocaudal delay. Blockade of glycinergic synaptic transmission by strychnine switched the alternating activity into synchronous bursting in the left and right sides as well as along the rostrocaudal axis. Whole cell recordings from motoneurons showed that they receive phasic synaptic inputs that were correlated with the locomotor activity recorded in ventral roots. This newly developed in vitro preparation of the adult zebrafish spinal cord will allow examination of the organization of the spinal locomotor network in an adult system to complement studies in zebrafish larvae and new born rodents.
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