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Sökning: WFRF:(Carini Gabriella) > (2021) > Ptychographic wavef...

Ptychographic wavefront characterization for single-particle imaging at x-ray lasers

Daurer, Benedikt J. (författare)
Uppsala universitet,Molekylär biofysik,Centre for BioImaging Sciences, National University of Singapore, Singapore 117557, Singapore; Diamond Light Source, Harwell Science & Innovation Campus, Didcot OX11 0DE, UK,Natl Univ Singapore, Ctr Bioimaging Sci, Singapore 117557, Singapore.;Uppsala Univ, Lab Mol Biophys, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.;Harwell Sci & Innovat Campus, Diamond Light Source, Didcot OX11 0DE, Oxon, England.
Sala, Simone (författare)
Diamond Light Source, Harwell Science & Innovation Campus, Didcot OX11 0DE, UK; Department of Physics & Astronomy, University College London, London WC1E 6BT, UK; Department of Physics & Astronomy, University of Southampton, Southampton SO17 1BJ, UK,Harwell Sci & Innovat Campus, Diamond Light Source, Didcot OX11 0DE, Oxon, England.;UCL, Dept Phys & Astron, London W E 6BT, England.;Univ Southampton, Dept Phys & Astron, Southampton SO17 1BJ, Hants, England.
Hantke, Max (författare)
Physical and Theoretical Chemistry Laboratory, Oxford University, Oxford OX1 3QZO, UK,Univ Oxford, Phys & Theoret Chem Lab, Oxford OX1 3QZO, England.
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Reddy, Hemanth K.N. (författare)
Uppsala universitet,Molekylär biofysik,Uppsala Univ, Lab Mol Biophys, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.
Bielecki, Johan (författare)
Uppsala universitet,Molekylär biofysik,Uppsala Univ, Lab Mol Biophys, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.;European XFEL GmbH, Holzkoppel 4, D-22869 Schenefeld, Germany.
Shen, Zhou (författare)
Centre for BioImaging Sciences, National University of Singapore, Singapore 117557, Singapore; Department of Physics, National University of Singapore, Singapore 117557, Singapore,Natl Univ Singapore, Ctr Bioimaging Sci, Singapore 117557, Singapore.;Natl Univ Singapore, Dept Phys, Singapore 117557, Singapore.
Nettelblad, Carl, 1985- (författare)
Uppsala universitet,Avdelningen för beräkningsvetenskap,Tillämpad beräkningsvetenskap,Science for Life Laboratory, SciLifeLab,Molekylär biofysik,Uppsala Univ, Lab Mol Biophys, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.;Uppsala Univ, Div Sci Comp, Dept Informat Technol, Sci Life Lab, SE-75105 Uppsala, Sweden.,Uppsala Univ, Lab Mol Biophys, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.;Lawrence Berkeley Natl Lab, NERSC, Berkeley, CA 94720 USA.,NERSC, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
Svenda, Martin (författare)
KTH,Uppsala universitet,Molekylär biofysik,Department of Applied Physics, Biomedical and X-Ray Physics, KTH—Royal Institute of Technology, SE 10691 Stockholm, Sweden,Biomedicinsk fysik och röntgenfysik,Uppsala Univ, Lab Mol Biophys, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.;KTH Royal Inst Technol, Dept Appl Phys Biomed & Xray Phys, SE-10691 Stockholm, Sweden.
Ekeberg, Tomas, 1983- (författare)
Uppsala universitet,Molekylär biofysik,Uppsala Univ, Lab Mol Biophys, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden.
Carini, Gabriella A. (författare)
SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA; Brookhaven National Laboratory, Upton, New York 11973, USA,SLAC Natl Accelerator Lab, 2575 Sand Hill Rd, Menlo Pk, CA 94025 USA.;Brookhaven Natl Lab, Upton, NY 11973 USA.
Hart, Philip (författare)
SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA,SLAC Natl Accelerator Lab, 2575 Sand Hill Rd, Menlo Pk, CA 94025 USA.
Osipov, Timur (författare)
SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA,SLAC Natl Accelerator Lab, 2575 Sand Hill Rd, Menlo Pk, CA 94025 USA.
Aquila, Andrew (författare)
SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA
Loh, N. Duane (författare)
Centre for BioImaging Sciences, National University of Singapore, Singapore 117557, Singapore; Department of Physics, National University of Singapore, Singapore 117557, Singapore,Natl Univ Singapore, Ctr Bioimaging Sci, Singapore 117557, Singapore.;Natl Univ Singapore, Dept Phys, Singapore 117557, Singapore.
Maia, Filipe R.N.C. (författare)
Uppsala universitet,Molekylär biofysik,NERSC, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
Thibault, Pierre (författare)
Diamond Light Source, Harwell Science & Innovation Campus, Didcot OX11 0DE, UK; Department of Physics & Astronomy, University of Southampton, Southampton SO17 1BJ, UK; Universitá degli Studi di Trieste, Trieste 34127, Italy,Harwell Sci & Innovat Campus, Diamond Light Source, Didcot OX11 0DE, Oxon, England.;Univ Southampton, Dept Phys & Astron, Southampton SO17 1BJ, Hants, England.;Univ Trieste, I-34127 Trieste, Italy.
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 (creator_code:org_t)
Optical Society of America, 2021
2021
Engelska.
Ingår i: Optica. - : Optical Society of America. - 2334-2536. ; 8:4, s. 551-562
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • A well-characterized wavefront is important for many x-ray free-electron laser (XFEL) experiments, especially for single-particle imaging (SPI), where individual biomolecules randomly sample a nanometer region of highly focused femtosecond pulses. We demonstrate high-resolution multiple-plane wavefront imaging of an ensemble of XFEL pulses, focused by Kirkpatrick–Baez mirrors, based on mixed-state ptychography, an approach letting us infer and reduce experimental sources of instability. From the recovered wavefront profiles, we show that while local photon fluence correction is crucial and possible for SPI, a small diversity of phase tilts likely has no impact. Our detailed characterization will aid interpretation of data from past and future SPI experiments and provides a basis for further improvements to experimental design and reconstruction algorithms.

Ämnesord

NATURVETENSKAP  -- Biologi -- Biofysik (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Biophysics (hsv//eng)
NATURVETENSKAP  -- Fysik -- Atom- och molekylfysik och optik (hsv//swe)
NATURAL SCIENCES  -- Physical Sciences -- Atom and Molecular Physics and Optics (hsv//eng)

Nyckelord

Femtosecond pulses
Imaging techniques
Reconstruction algorithms
Synchrotron radiation
Wave front sensing
X ray lasers
Physics with specialization in Biophysics
Fysik med inriktning mot biofysik

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