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- Reimerdes, H., et al.
(författare)
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Overview of the TCV tokamak experimental programme
- 2022
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 62:4
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Tidskriftsartikel (refereegranskat)abstract
- The tokamak a configuration variable (TCV) continues to leverage its unique shaping capabilities, flexible heating systems and modern control system to address critical issues in preparation for ITER and a fusion power plant. For the 2019-20 campaign its configurational flexibility has been enhanced with the installation of removable divertor gas baffles, its diagnostic capabilities with an extensive set of upgrades and its heating systems with new dual frequency gyrotrons. The gas baffles reduce coupling between the divertor and the main chamber and allow for detailed investigations on the role of fuelling in general and, together with upgraded boundary diagnostics, test divertor and edge models in particular. The increased heating capabilities broaden the operational regime to include T (e)/T (i) similar to 1 and have stimulated refocussing studies from L-mode to H-mode across a range of research topics. ITER baseline parameters were reached in type-I ELMy H-modes and alternative regimes with 'small' (or no) ELMs explored. Most prominently, negative triangularity was investigated in detail and confirmed as an attractive scenario with H-mode level core confinement but an L-mode edge. Emphasis was also placed on control, where an increased number of observers, actuators and control solutions became available and are now integrated into a generic control framework as will be needed in future devices. The quantity and quality of results of the 2019-20 TCV campaign are a testament to its successful integration within the European research effort alongside a vibrant domestic programme and international collaborations.
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- Pucella, G., et al.
(författare)
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Overview of the FTU results
- 2022
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 62:4
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Forskningsöversikt (refereegranskat)abstract
- Since the 2018 IAEA FEC Conference, FTU operations have been devoted to several experiments covering a large range of topics, from the investigation of the behaviour of a liquid tin limiter to the runaway electrons mitigation and control and to the stabilization of tearing modes by electron cyclotron heating and by pellet injection. Other experiments have involved the spectroscopy of heavy metal ions, the electron density peaking in helium doped plasmas, the electron cyclotron assisted start-up and the electron temperature measurements in high temperature plasmas. The effectiveness of the laser induced breakdown spectroscopy system has been demonstrated and the new capabilities of the runaway electron imaging spectrometry system for in-flight runaways studies have been explored. Finally, a high resolution saddle coil array for MHD analysis and UV and SXR diamond detectors have been successfully tested on different plasma scenarios.
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- Mohanta, S. K., et al.
(författare)
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Neuroimmune cardiovascular interfaces control atherosclerosis
- 2022
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 605, s. 152-159
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Tidskriftsartikel (refereegranskat)abstract
- Atherosclerotic plaques develop in the inner intimal layer of arteries and can cause heart attacks and strokes(1). As plaques lack innervation, the effects of neuronal control on atherosclerosis remain unclear. However, the immune system respondsto plaques by forming leukocyte infiltrates in the outer connective tissue coat of arteries (the adventitia)(2-6). Here, because the peripheral nervous system uses the adventitia as its principal conduit to reach distant targets(7-9), we postulated that the peripheral nervous system may directly interact with diseased arteries. Unexpectedly, widespread neuroimmune cardiovascular interfaces (NICIs) arose in mouse and human atherosclerosis-diseased adventitia segments showed expanded axon networks, includinggrowth cones at axon endings near immune cells and media smooth muscle cells. Mouse NICIs established a structural artery-brain circuit (ABC): abdominal adventitia nociceptive afferents(10-14) entered the central nervous system through spinal cord T-6-T-13 dorsal root ganglia and were traced to higher brain regions, including the parabrachial and central amygdala neurons; and sympathetic efferent neurons projected from medullary and hypothalamic neuronsto the adventitia through spinal intermediolateral neurons and both coeliac and sympathetic chain ganglia. Moreover, ABC peripheral nervous system components were activated: splenic sympathetic and coeliac vagus nerve activities increased in parallel to disease progression, whereas coeliacganglionectomy led to the disintegration of adventitial NICIs, reduced disease progression and enhanced plaque stability. Thus, the peripheral nervous system uses NICIs to assemble a structural ABC, and therapeutic intervention in the ABC attenuates atherosclerosis.
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- Cuesta, A., et al.
(författare)
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Gender and Public Perception of Disasters : A Multiple Hazards Exploratory Study of EU Citizens
- 2022
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Ingår i: Safety. - : MDPI. - 2313-576X. ; 8:3
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Tidskriftsartikel (refereegranskat)abstract
- Aim: To explore gender influence on individual risk perception of multiple hazards and personal attitudes towards disaster preparedness across EU citizens. Method: An online survey was distributed to 2485 participants from Spain, France, Poland, Sweden and Italy. The survey was divided into two parts. The first part examined perceived likelihood (L), perceived personal impact (I) and perceived self-efficacy (E) towards disasters due to extreme weather conditions (flood, landslide and storm), fire, earthquake, hazardous materials accidents, and terrorist attacks. The overall risk rating for each specific hazard was measured through the following equation R = (L × I)/E and the resulting scores were brought into the range between 0 and 1. The second part explored people’s reactions to the Pros and Cons of preparedness to compute the overall attitudes of respondents towards preparation (expressed as a ratio between −1 and 1). Results: Although we found gender variations on concerns expressed as the likelihood of the occurrence, personal consequences and self-efficacy, the overall risks were judged significantly higher by females in all hazards (p < 0.01). We also found that, in general, most respondents (both males and females) were in favour of preparedness. More importantly, despite the gender differences in risk perception, there were no significant differences in the attitudes towards preparedness. We found weak correlations between risks perceived and attitudes towards preparedness (rho < 0.20). The intersectional analysis showed that young and adult females perceived higher risks than their gender counterparts at the same age. There were also gender differences in preparedness, i.e., females in higher age ranges are more motivated for preparedness than men in lower age ranges. We also found that risk perception for all hazards in females was significantly higher than in males at the same education level. We found no significant differences between sub-groups in the pros and cons of getting ready for disasters. However, females at a higher level of education have more positive attitudes towards preparedness. Conclusions: This study suggests that gender along with other intersecting factors (e.g., age and education) still shape differences in risk perception and attitudes towards disasters across the EU population. Overall, the presented results policy actions focus on promoting specific DRR policies and practices (bottom-up participatory and learning processes) through interventions oriented to specific target groups from a gender perspective. © 2022 by the authors.
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