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- Khatri, C, et al.
(författare)
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Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
- 2021
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Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 11:11, s. e050830-
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Tidskriftsartikel (refereegranskat)abstract
- Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.ResultsThis study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p<0.001), age >80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).ConclusionsPatients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration numberNCT04323644
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| 4. |
- Zouganelis, I., et al.
(författare)
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The Solar Orbiter Science Activity Plan : Translating solar and heliospheric physics questions into action
- 2020
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Ingår i: Astronomy and Astrophysics. - : EDP SCIENCES S A. - 0004-6361 .- 1432-0746. ; 642
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Tidskriftsartikel (refereegranskat)abstract
- Solar Orbiter is the first space mission observing the solar plasma both in situ and remotely, from a close distance, in and out of the ecliptic. The ultimate goal is to understand how the Sun produces and controls the heliosphere, filling the Solar System and driving the planetary environments. With six remote-sensing and four in-situ instrument suites, the coordination and planning of the operations are essential to address the following four top-level science questions: (1) What drives the solar wind and where does the coronal magnetic field originate?; (2) How do solar transients drive heliospheric variability?; (3) How do solar eruptions produce energetic particle radiation that fills the heliosphere?; (4) How does the solar dynamo work and drive connections between the Sun and the heliosphere? Maximising the mission's science return requires considering the characteristics of each orbit, including the relative position of the spacecraft to Earth (affecting downlink rates), trajectory events (such as gravitational assist manoeuvres), and the phase of the solar activity cycle. Furthermore, since each orbit's science telemetry will be downloaded over the course of the following orbit, science operations must be planned at mission level, rather than at the level of individual orbits. It is important to explore the way in which those science questions are translated into an actual plan of observations that fits into the mission, thus ensuring that no opportunities are missed. First, the overarching goals are broken down into specific, answerable questions along with the required observations and the so-called Science Activity Plan (SAP) is developed to achieve this. The SAP groups objectives that require similar observations into Solar Orbiter Observing Plans, resulting in a strategic, top-level view of the optimal opportunities for science observations during the mission lifetime. This allows for all four mission goals to be addressed. In this paper, we introduce Solar Orbiter's SAP through a series of examples and the strategy being followed.
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| 5. |
- Upsdell, E. W., et al.
(författare)
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The XMM cluster survey : exploring scaling relations and completeness of the dark energy survey year 3 redMaPPer cluster catalogue
- 2023
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 522:4, s. 5267-5290
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Tidskriftsartikel (refereegranskat)abstract
- We cross-match and compare characteristics of galaxy clusters identified in observations from two sky surveys using two completely different techniques. One sample is optically selected from the analysis of 3 years of Dark Energy Survey observations using the redMaPPer cluster detection algorithm. The second is X-ray selected from XMM observations analysed by the XMM Cluster Survey. The samples comprise a total area of 57.4 deg(2), bounded by the area of four contiguous XMM survey regions that overlap the DES footprint. We find that the X-ray-selected sample is fully matched with entries in the redMaPPer catalogue, above lambda > 20 and within 0.1 < z < 0.9. Conversely, only 38 per cent of the redMaPPer catalogue is matched to an X-ray extended source. Next, using 120 optically clusters and 184 X-ray-selected clusters, we investigate the form of the X-ray luminosity-temperature (L-X -T-X ), luminosity-richness (L-X - lambda), and temperature-richness (T-X - lambda) scaling relations. We find that the fitted forms of the L-X -T-X relations are consistent between the two selection methods and also with other studies in the literature. However, we find tentative evidence for a steepening of the slope of the relation for low richness systems in the X-ray-selected sample. When considering the scaling of richness with X-ray properties, we again find consistency in the relations (i.e. L-X - lambda and T-X - lambda) between the optical and X-ray-selected samples. This is contrary to previous similar works that find a significant increase in the scatter of the luminosity scaling relation for X-ray-selected samples compared to optically selected samples.
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| 6. |
- Rodriguez-Kamenetzky, A., et al.
(författare)
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Characterizing the radio continuum nature of sources in the massive star-forming region W75N (B)
- 2020
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 496:3, s. 3128-3141
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Tidskriftsartikel (refereegranskat)abstract
- The massive star-forming region W75N (B) is thought to host a cluster of massive protostars (VLA 1, VLA 2, and VLA 3) undergoing different evolutionary stages. In this work, we present radio continuum data with the highest sensitivity and angular resolution obtained to date in this region, using the VLA-A and covering a wide range of frequencies (4-48 GHz), which allowed us to study the morphology and the nature of the emission of the different radio continuum sources. We also performed complementary studies with multi-epoch Very Large Array (VLA) data and Atacama Large Millimeter Array (ALMA) archive data at 1.3 mm wavelength. We find that VLA 1 is driving a thermal radio jet at scales of approximate to 0.1 arcsec (approximate to 130 au), but also shows signs of an incipient hypercompact HII region at scales of less than or similar to 1 arcsec (less than or similar to 1300 au). VLA 3 is also driving a thermal radio jet at scales of a few tenths of arcsec (few hundred of au). We conclude that this jet is shock exciting the radio continuum sources Bc and VLA 4 (obscured Herbig-Haro objects), which show proper motions moving outward from VLA 3 at velocities of approximate to 112-118 km s(-1). We have also detected three new weak radio continuum sources, two of them associated with millimetre continuum cores observed with ALMA, suggesting that these two sources are also embedded young stellar objects in this massive star-forming region.
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| 7. |
- Gomez, J. F., et al.
(författare)
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An SiO Toroid and Wide-angle Outflow Associated with the Massive Protostar W75N(B)-VLA2
- 2023
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Ingår i: Astrophysical Journal Letters. - 2041-8213 .- 2041-8205. ; 956:2
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Tidskriftsartikel (refereegranskat)abstract
- We have carried out Atacama Large Millimeter/submillimeter Array observations of the massive star-forming region W75N(B), which contains the massive protostars VLA1, VLA2, and VLA3. Particularly, VLA2 is an enigmatic protostar associated with a wind-driven H2O maser shell, which has evolved from an almost isotropic outflow to a collimated one in just 20 yr. The shell expansion seemed to be halted by an obstacle located to the northeast of VLA2. Here we present our findings from observing the 1.3 mm continuum and H2CO and SiO emission lines. Within a region of ∼30″ (∼39,000 au) diameter, we have detected 40 compact millimeter continuum sources, three of them coinciding with VLA1, VLA2, and VLA3. While the H2CO emission is mainly distributed in a fragmented structure around the three massive protostars, but without any of the main H2CO clumps spatially coinciding with them, the SiO is highly concentrated on VLA2, indicating the presence of very strong shocks generated near this protostar. The SiO emission is clearly resolved into an elongated structure (∼0.″6 × 0.″3; ∼780 au×390 au) perpendicular to the major axis of the wind-driven maser shell. The structure and kinematics of the SiO emission are consistent with a toroid and a wide-angle outflow surrounding a central mass of ∼10 M ⊙, thus supporting previous theoretical predictions regarding the evolution of the outflow. Additionally, we have identified the expected location and estimated the gas density of the obstacle that is hindering the expansion of the maser shell.
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| 8. |
- Surcis, G., et al.
(författare)
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Monitoring of the polarized H 2 O maser emission around the massive protostars W75N(B)-VLA 1 and W75N(B)-VLA 2
- 2023
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 673
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Tidskriftsartikel (refereegranskat)abstract
- Context. Several radio sources have been detected in the high-mass star-forming region W75N(B), with the massive young stellar objects VLA 1 and VLA 2 shown to be of particular interest among them. These objects are thought to be at different evolutionary stages: VLA 1 is in the early stage of photoionization and driving a thermal radio jet, while VLA 2 is a thermal, collimated ionized wind surrounded by a dusty disk or envelope. In both sources, 22 GHz H2O masers have been detected in the past. Those around VLA 1 show a persistent linear distribution along the thermal radio jet, while those around VLA 2 have traced the evolution from a non-collimated to a collimated outflow over a period of ~20 yr. The magnetic field inferred from the H2O masers has shown an orientation rotation following the direction of the major-axis of the shell around VLA 2, whereas it is immutable around VLA 1. Aims. By monitoring the polarized emission of the 22 GHz H2O masers around both VLA 1 and VLA 2 over a period of six years, we aim to determine whether the H2O maser distributions show any variation over time and whether the magnetic field behaves accordingly. Methods. The European VLBI Network was used in full polarization and phase-reference mode in order to determine the absolute positions of the 22 GHz H2O masers with a beam size of ~1 mas and to determine the orientation and the strength of the magnetic field. We observed four epochs separated by two years from 2014 to 2020. Results. We detected polarized emission from the H2O masers around both VLA 1 and VLA 2 in all the epochs. By comparing the H2O masers detected in the four epochs, we find that the masers around VLA 1 are tracing a nondissociative shock originating from the expansion of the thermal radio jet, while the masers around VLA 2 are tracing an asymmetric expansion of the gas that is halted in the northeast where the gas likely encounters a very dense medium. We also found that the magnetic field inferred from the H2O masers in each epoch can be considered as a portion of a quasi-static magnetic field estimated in that location rather than in that time. This allowed us to study the morphology of the magnetic field around both VLA 1 and VLA 2 locally across a larger area by considering the vectors estimated in all the epochs as a whole. We find that the magnetic field in VLA 1 is located along the jet axis, bending toward the north and south at the northeasterly and southwesterly ends of the jet, respectively, reconnecting with the large-scale magnetic field. The magnetic field in VLA 2 is perpendicular to the expansion directions until it encounters the denser matter in the northeast, where the magnetic field is parallel to the expansion direction and agrees with the large-scale magnetic field. We also measured the magnetic field strength along the line of sight in three of the four epochs, with resulting values of -764mG
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