| 1. |
- Szymanski, J. J., et al.
(author)
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MEGA : A search for the decay mu –> e gamma
- 1994
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In: Intersections between particle and nuclear physics. Proceedings, 5th Conference, St. Petersburg, USA, May 31-June 6, 1994. ; , s. 789-792
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Conference paper (peer-reviewed)
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| 2. |
- Chang-Chun, Chen, et al.
(author)
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Nucleoside transport inhibition mediates lidoflazine-induced cardioprotection during intermittent aortic crossclamping
- 1992
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In: Journal of Thoracic and Cardiovascular Surgery. - : Elsevier. - 0022-5223 .- 1097-685X. ; 104:6, s. 1602-1609
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Journal article (peer-reviewed)abstract
- The effects of pretreatment with the nucleoside transport inhibitor lidoflazine on repeated ischemia-reperfusion injury induced by normothermic intermittent aortic crossclamping were studied in canine hearts. Eighteen mongrel dogs were allocated to three groups: placebo (n = 6), lidoflazine (1 mg/kg) (n = 6), and lidoflazine (1 mg/kg) plus the adenosine receptor blocker aminophylline (7 mg/kg) (n = 6). Pretreatment was performed intravenously during 15 minutes before extracorporeal circulation. All hearts were subjected to four intervals of 15 minutes of global ischemia each followed by 10 minutes of reperfusion. After weaning from extracorporeal circulation, functional recovery was followed for 1 hour. In the lidoflazine group, myocardial adenosine content (0.25 +/- 0.06 mumol/gm dry weight) was 3.5 times higher than that in the control group (0.07 +/- 0.03 mumol/gm dry weight; p < 0.05) at the end of the last aortic crossclamping. The release of adenosine from the myocardium during each reperfusion period was significantly higher than that in the control group (p < 0.05). Myocardial extraction of lactate was normalized at every reperfusion interval in the lidoflazine group but not in the control group (p < 0.05). In the lidoflazine group functional recovery was significantly better than that in the control group. Positive rate of rise of pressure, negative rate of rise of pressure, and cardiac output recovered to, respectively, 150% +/- 19%, 82% +/- 8%, and 131% +/- 15% in the lidoflazine group versus, respectively, 37% +/- 9%, 23% +/- 7%, and 29% +/- 8% in the control group (p < 0.001) at 1 hour after extracorporeal circulation. When the adenosine receptor blocker aminophylline was administered in association with lidoflazine, protection dropped significantly: positive and negative rate of rise of pressure and cardiac output were, respectively, 58% +/- 8%, 46% +/- 9%, and 67% +/- 16% at 1 hour after extracorporeal circulation (p < 0.05 versus lidoflazine alone). These results suggest that the cardioprotective effects of lidoflazine are at least in part mediated by adenosine receptor stimulation via nucleoside transport inhibition-induced accumulation of endogenous adenosine in the myocardium.
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| 3. |
- Chen, F., et al.
(author)
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Evaluation of a workstation for letter sorting in the Beijing post office
- 1993
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In: Occupational and environmental economics. - : Indian Society of Ergonomics.. - 819005080X ; , s. 61-66
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Conference paper (peer-reviewed)abstract
- In the Chinese postal system, letters are sorted manually using a sorting frame, consisting of vertical and horizontal arrays of pigeon-holes of different dimensions. Letter sorting is a time consuming and a mentally intensive task involving repetitive movements of shoulder and hand muscles. Musculoskeletal complaints and disorders of the lower back, shoulder and hand occur frequently among the letter sorting workers. A total of 293 letter-sorters (71 males and 222 females) from Beijing Postal Sorting Office were subjected to a general health check-up including musculoskeletal disorders coupled with administration of a questionnaire. The worker's daily work load was evaluated by counting the number of letters sorted in each pigeon-hole in the sorting frame and also by considering their arm movements and body postures. The workplace dimensions were also measured. Results revealed that 62.1% of the workers complained of low back pain, 78.5% of shoulder pain and 48.8% of hand pain. A high percentage of workers seemed to have mental intensive symptoms, such as, headache, dizziness and drowsiness. Almost 25% of the female wokers indicated irregularity in their menstruation. An improved ergonomic design of the sorting frame is recommended.
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