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Global burden of pr...
Global burden of primary liver cancer and its asso- ciation with underlying aetiologies, sociodemo- graphic status, and sex differences from 1990-2019: A DALY-based analysis of the Global Burden of Disease 2019 study
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- Choi, Sungchul (författare)
- Yonsei Univ, South Korea
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- Kim, Beom Kyung (författare)
- Yonsei Univ, South Korea; Yonsei Univ, South Korea; Yonsei Univ Hlth Syst, South Korea
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- Yon, Dong Keon (författare)
- Kyung Hee Univ, South Korea
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- Lee, Seung Won (författare)
- Sungkyunkwan Univ, South Korea
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- Lee, Han Gyeol (författare)
- Yonsei Univ, South Korea
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- Chang, Ho Hyeok (författare)
- Yonsei Univ, South Korea
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- Park, Seoyeon (författare)
- Yonsei Univ, South Korea
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- Koyanagi, Ai (författare)
- CIBERSAM, Spain; Pg Lluis Co 23, Spain
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- Jacob, Louis (författare)
- CIBERSAM, Spain; Univ Paris Cite, France
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- Dragioti, Elena (författare)
- Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Smärt och rehabiliteringscentrum
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- Radua, Joaquim (författare)
- Univ Barcelona, Spain; Karolinska Inst, Sweden; Kings Coll London, England
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- Shin, Jae Il (författare)
- Yonsei Univ, South Korea
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- Kim, Seung Up (författare)
- Yonsei Univ, South Korea; Yonsei Univ, South Korea; Yonsei Univ Hlth Syst, South Korea
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- Smith, Lee (författare)
- Anglia Ruskin Univ, England
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(creator_code:org_t)
- 2023-01-04
- 2023
- Engelska.
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Ingår i: Clinical and Molecular Hepatology. - : KOREAN ASSOC STUDY LIVER. - 2287-2728 .- 2287-285X. ; 29:2, s. 433-452
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background/Aims: Global distribution of dominant liver cancer aetiologies has significantly changed over the past decades. This study analyzed the updated temporal trends of liver cancer aetiologies and sociodemographic status in 204 countries and territories from 1990 to 2019.Methods: The Global Burden of Disease 2019 report was used for statistical analysis. In addition, we performed stratification analysis to five quintiles using sociodemographic index and 21 geographic regions.Results: The crude numbers of liver cancer disease-adjusted life years (DALYs) and deaths significantly increased during the study period (DALYs; 11,278,630 in 1990 and 12,528,422 in 2019, deaths; 365,215 in 1990 and 484,577 in 2019). However, the Age-standardized DALY and mortality rates decreased. Hepatitis B virus (HBV) remains the leading cause of liver cancer DALYs and mortality, followed by hepatitis C virus (HCV), alcohol consumption, and non-alcoholic steatohepatitis/non-alcoholic fatty liver disease (NASH/NAFLD). Although Age-standardized DALY and mortality rates of liver cancer due to HBV and HCV have decreased, the rates due to alcohol consumption and NASH/NAFLD have increased. In 2019, the population of the East Asia region had the highest Age-standardized DALY and mortality rates, followed by high-income Asia-Pacific and Central Asia populations. Although East Asia and high-income Asia-Pacific regions showed a decrease during the study period, Age-standardized DALY rates increased in Central Asia. High-income North American and Australasian populations also showed a significant increase in Age-standardized DALY.Conclusions: Liver cancer remains an ongoing global threat. The burden of liver cancer associated with alcohol consumption and NASH/NAFLD is markedly increasing and projected to continuously increase. (Clin Mol Hepatol 2023;29:433-452)
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Beroendelära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Substance Abuse (hsv//eng)
Nyckelord
- Global burden; Primary liver cancer; Incidence; Mortality; Aetiology
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- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Choi, Sungchul
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Kim, Beom Kyung
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Yon, Dong Keon
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Lee, Seung Won
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Lee, Han Gyeol
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Chang, Ho Hyeok
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Park, Seoyeon
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Koyanagi, Ai
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Jacob, Louis
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Dragioti, Elena
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Radua, Joaquim
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Shin, Jae Il
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Kim, Seung Up
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Smith, Lee
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- MEDICIN OCH HÄLSOVETENSKAP
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och Hälsovetenskap
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och Beroendelära
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Clinical and Mol ...
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Linköpings universitet
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Karolinska Institutet