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Träfflista för sökning "WFRF:(Chou S) srt2:(2000-2004)"

Sökning: WFRF:(Chou S) > (2000-2004)

  • Resultat 1-9 av 9
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1.
  • Bakajin, O., et al. (författare)
  • Separation of 100-kilobase DNA molecules in 10 seconds
  • 2001
  • Ingår i: Analytical Chemistry. - : American Chemical Society (ACS). - 0003-2700 .- 1520-6882. ; 73:24, s. 6053-6056
  • Tidskriftsartikel (refereegranskat)abstract
    • Long double-stranded DNA molecules were separated in microfabricated hexagonal arrays in less than 1 min, several orders of magnitude faster than by using conventional technology. DNA samples were first concentrated at the entrance to the array in a thin band by entropic focusing. They were then separated by pulsed field electrophoresis. T4 (168.9 kbp) and λ (48.5 kbp) DNAs could be resolved into two clearly separated bands in ∼10 s in these experiments. This corresponds to a mass resolution of 6% in 11 min in a 1-cm-long array.
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  • Tegenfeldt, Jonas O., et al. (författare)
  • Near-field scanner for moving molecules
  • 2001
  • Ingår i: Physical Review Letters. - 0031-9007. ; 86:7, s. 1378-1381
  • Tidskriftsartikel (refereegranskat)abstract
    • A new technology that provides high optical resolution as well as very high data rates for moving molecules is presented. An important aspect of the device is the dependence of both the near-field radiation pattern and the far-field transmission of a thin slit on the polarization of the incident light.
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9.
  • Tegenfeldt, Jonas, et al. (författare)
  • The dynamics of genomic-length DNA molecules in 100-nm channels
  • 2004
  • Ingår i: Proceedings of the National Academy of Sciences. - : Proceedings of the National Academy of Sciences. - 1091-6490 .- 0027-8424. ; 101:30, s. 10979-10983
  • Tidskriftsartikel (refereegranskat)abstract
    • We show that genomic-length DNA molecules imaged in nano-channels have an extension along the channel that scales linearly with the contour length of the polymer, in agreement with the scaling arguments developed by de Gennes for self-avoiding confined polymers. This fundamental relationship allows us to measure directly the contour length of single DNA molecules confined in the channels, and the statistical analysis of the dynamics of the polymer in the nanochannel allows us to compute the SD of the mean of the extension. This statistical analysis allows us to measure the extension of A DNA multimers with a 130-nm SD in 1 min.
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  • Resultat 1-9 av 9

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