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- Johansson, Pär, et al.
(författare)
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Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants : a study in the rabbit tibia
- 2014
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Ingår i: International Journal of Nanomedicine. - : Nakladatelstvi Lidove noviny. - 1176-9114 .- 1178-2013. ; 9, s. 3903-3911
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Tidskriftsartikel (refereegranskat)abstract
- Polyether ether ketone (PEEK) is today frequently used as a biomaterial in different medical operations due to its excellent mechanical and chemical properties. However, the untreated surface of PEEK is bio-inert, hydrophobic and does not osseointegrate in its pure form. The aim of this study was to evaluate a unique nano modified surface of PEEK with respect to osseointegration. Forty-eight threaded, non-cutting PEEK implants were inserted bilaterally in the tibia of 24 rabbits. Half of the implants (n = 24) were coated with nanocrystalline hydroxyapatite (test) and the remaining implants (n = 24) were left uncoated (control). Half of the animals (n = 12) were euthanized after 3 weeks of healing and the remaining (n = 12) after 12 weeks. The implant retention was measured with a removal torque apparatus. Surface analysis was performed with interferometry, scanning electron microscopy and X-ray photon spectroscopy to relate the removal torque to the applied surface. The test implants revealed a significantly higher retention after 3 weeks (p-value = 0.05) and 12 weeks (p-value = 0.028) compared to controls. The result of the present study proves that the addition of nanocrystalline HA coating to PEEK surfaces significantly increased its removal torque and biocompability.
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