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- Lutz, Barbara S., et al.
(författare)
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Nerve transfer to the median nerve using parts of the ulnar and radial nerves in the rabbit : effects on motor recovery of the median nerve and donor nerve morbidity
- 2000
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Ingår i: Journal of Hand Surgery - British and European Volume. - : SAGE Publications. - 0266-7681 .- 1532-2211. ; 25:4, s. 329-335
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Tidskriftsartikel (refereegranskat)abstract
- In this study, motor re-innervation of the median nerve by transfer of one-third, one-half, and two-thirds of either the agonistic ulnar nerve or the antagonistic radial nerve was investigated in both extremities of 20 rabbits.Recipient median nerve: Muscle contraction force of the flexor digitorum sublimus muscle after a one-third and a one-half of the ulnar nerve transfer achieved an average of 75 and 97% muscle power respectively as compared to conventional end-to-end neurorrhaphy. Muscle contraction force after one-third or one-half of the radial nerve transfer was significantly lower (36%).Donor nerves: Extensor carpi radialis muscle or flexor carpi ulnaris muscle contraction force 6 months postoperatively demonstrated a significant decrease after a one-half ulnar nerve and a two-thirds ulnar or radial nerve transfer, but not after a one-third transfer of either radial or ulnar nerves.Histologically, the number of axons in the re-innervated median nerve and both donor nerves distal to the coaptation site seemed to follow variable patterns.It was concluded that in the rabbit use of one-third of the agonistic ulnar nerve for re-innervation of the median nerve results in useful motor recovery with negligible donor site morbidity. Clinically, this technique may offer an alternative option for proximal nerve injuries or for free functioning muscle transplantations.
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| 2. |
- Chuang, S.S., et al.
(författare)
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Internal Reliability, Temporal Stability, and Correlates of Individual Differences in Paternal Involvement: A 15-year Longitudinal Study in Sweden
- 2004
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Ingår i: Conceptualizing and Measuring Father Involvement. - Erlbaum : Mahwah: Lawrence Erlbaum. - 0805843590
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The Swedish study began in 1981-2, with 6 waves of data collection. The participants were 144 Swedish families and their first-born children (70 girls) who averaged 16 months of age. This chapter focuses on the first 6 phases, when the children averaged 1, 2, 3, 7, 8 and 15 years of age. The issues that will be presented are on the stabilities of the various dimensions of father involvement over time and the possible factors that may influence their levels of involvement.
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| 3. |
- Chuang, S. S., et al.
(författare)
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Paternal leave and paternal involvement in Sweden
- 2003
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Ingår i: The biennial meeting of Society for Research in Child Development, Tampa, FL, April 24-27, 2003.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 4. |
- Chuang, S.S., et al.
(författare)
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Swedish adolescents’ relational and assertive self-concepts across social contexts and relationships.
- 2004
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Ingår i: Poster presented to the American Psychological Society Annual Convention, Chicago, May 28, 2004..
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Konferensbidrag (refereegranskat)abstract
- Participants were 118 15-year –old Swedish adolescents who rated themselves on assertive and relational traits across various types of roles and relationships (e.g., as a boy/girl, with peers, parents). Analysis revealed that the adolescents’ relational and assertive ratings were context-dependent. Girls’ relational and assertive scores were independent of each other whereas boys’ relational and assertive scores were negatively related for some types of relationships. These findings underscore that traits have greater variability across social contexts than by gender.
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| 9. |
- Lutz, Barbara S., et al.
(författare)
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Interposition of a pedicle fat flap significantly improves specificity of reinnervation and motor recovery after repair of transected nerves in adjacency in rats
- 2001
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Ingår i: Plastic and reconstructive surgery (1963). - 0032-1052 .- 1529-4242. ; 107:1, s. 116-123
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Tidskriftsartikel (refereegranskat)abstract
- Despite highest standards in nerve repair, functional recovery following nerve transection still remains unsatisfactory. Nonspecific reinnervation of target organs caused by misdirected axonal growth at the repair site is regarded as one reason for a poor functional outcome. This study was conducted to establish a method for preventing aberrant reinnervation between transected and repaired nerves in adjacency.Rat sciatic nerve was transected and repaired as follows: epineural sutures of the sciatic nerve (group A, n = 6), fascicular repair of tibial and peroneal nerves respectively (group B, n = 8), and, as in group B, separating both nerves using a pedicle fat flap as barrier (group C, n = 8). As control only, the tibial nerve was transected and repaired (group D, n = 5).Muscle contraction force of the gastrocnemius muscle was significantly higher in group C as compared with groups A and B after 4 months. Muscle weight showed significantly lower values in group A as compared with groups B, C, and D. Histologic examination in group C revealed little growth of axons from the tibial to the peroneal nerve and vice versa. This axon crossing was observed only when gaps between the fat cells were available. These findings were confirmed by a significantly lower rate of misdirected axonal growth as compared with groups A and B using sequential retrograde double labeling technique of the soleus motoneuron pool.We conclude that a pedicle fat flap significantly prevents aberrant reinnervation between repaired adjacent nerves resulting in significantly improved motor recovery in rats. Clinically, this is of importance for brachial plexus, sciatic nerve, and facial nerve repair.
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| 10. |
- Lutz, Barbara S., et al.
(författare)
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Specificity of reinnervation and motor recovery after interposition of an artificial barrier between transected and repaired nerves in adjacency : an experimental study in the rat
- 2001
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Ingår i: Acta Neurochirurgica. - : Springer Science and Business Media LLC. - 0001-6268 .- 0942-0940. ; 143:4, s. 393-399
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Tidskriftsartikel (refereegranskat)abstract
- Non-specific re-innervation of target organs caused by misdirected axonal growth at the repair site is regarded as one reason for a poor functional outcome after peripheral nerve transsection and repair. This study investigates the rate of aberrant re-innervation and its influence on motor recovery in the rat sciatic nerve using artificial sheets as barrier between tibial and peroneal nerves.The sciatic nerve was transsected and repaired as follows: epineural sutures (A × 6), fascicular repair of tibial and peroneal nerves respectively (B × 8), and the same as in group B, but separating both nerves using an Integra®-sheet with silicone (C × 8), or Integra® without silicone (D × 8). As control, solely the tibial nerve was transsected and repaired (E × 5).Final investigations after 4 months revealed that in group C, 50% of the Integra®-silicone sheets were dislocated. No dislocation was found in group D. Muscle contraction force of the gastrocnemius muscle was significantly higher in group E as compared to all other groups. However although not significant, group D showed a consistently higher muscle contraction force than groups A, B, and C. Histology in groups A, B, and C with dislocated sheets demonstrated multiple axons growing from the tibial to the peroneal nerve and vice versa. In groups D and E, no such axonal growth was visible. These findings were confirmed by a significantly higher rate of specific re-innervation of the soleus muscle using sequential retrograde double labelling technique.Results of this study suggest that an artificial sheet such as Integra® bears the potential of preventing aberrant re-innervation between repaired adjacent nerves resulting in improved motor recovery. Clinically, this technique may be of importance for brachial plexus, sciatic nerve, and facial nerve repair.
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