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2022 EULAR recommen...
2022 EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in adults with autoimmune inflammatory rheumatic diseases
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- Fragoulis, George E. (författare)
- Glasgow Royal Infirmary,National and Kapodistrian University of Athens
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- Nikiphorou, Elena (författare)
- King's College London
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- Dey, Mrinalini (författare)
- University of Liverpool
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- Zhao, Sizheng Steven (författare)
- Centre for Epidemiology Versus Arthritis
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- Courvoisier, Delphine Sophie (författare)
- Geneva University Hospital
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- Arnaud, Laurent (författare)
- University Hospital Of Strasbourg
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- Atzeni, Fabiola (författare)
- University of Messina
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- Behrens, Georg M.N. (författare)
- Hannover Medical School
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- Bijlsma, Johannes W.J. (författare)
- University Medical Center Utrecht
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Böhm, Peter (författare)
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- Constantinou, Costas A. (författare)
- Cyprus Ministry of Health
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Garcia-Diaz, Silvia (författare)
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- Kapetanovic, Meliha Crnkic (författare)
- Lund University,Lunds universitet,Lund Arthritis Research Group (LARG),Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital
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- Lauper, Kim (författare)
- Centre for Epidemiology Versus Arthritis,University of Geneva
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- Luís, Mariana (författare)
- University Hospital of Coimbra
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- Morel, Jacques (författare)
- Montpellier University Hospital
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- Nagy, György (författare)
- Semmelweis University
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- Poleverino, Eva (författare)
- Vall d'Hebron University Hospital
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Van Rompay, Jef (författare)
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- Sebastiani, Marco (författare)
- University of Modena and Reggio Emilia
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- Strangfeld, Anja (författare)
- Charité - University Medicine Berlin
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- De Thurah, Annette (författare)
- Aarhus University Hospital
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- Galloway, James (författare)
- King's College London
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- Hyrich, Kimme L. (författare)
- Manchester Academic Health Science Centre,Centre for Epidemiology Versus Arthritis
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(creator_code:org_t)
- 2022-11-03
- 2023
- Engelska.
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Ingår i: Annals of the Rheumatic Diseases. - : BMJ. - 0003-4967 .- 1468-2060. ; 82:6, s. 742-753
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Objectives: To develop EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in patients with autoimmune inflammatory rheumatic diseases (AIIRD). Methods: An international Task Force (TF) (22 members/15 countries) formulated recommendations, supported by systematic literature review findings. Level of evidence and grade of recommendation were assigned for each recommendation. Level of agreement was provided anonymously by each TF member. Results: Four overarching principles (OAP) and eight recommendations were developed. The OAPs highlight the need for infections to be discussed with patients and with other medical specialties, in accordance with national regulations. In addition to biologic/targeted synthetic disease-modifying antirheumatic drugs (DMARDs) for which screening for latent tuberculosis (TB) should be performed, screening could be considered also before conventional synthetic DMARDs, glucocorticoids and immunosuppressants. Interferon gamma release assay should be preferred over tuberculin skin test, where available. Hepatitis B (HBV) antiviral treatment should be guided by HBV status defined prior to starting antirheumatic drugs. All patients positive for hepatitis-C-RNA should be referred for antiviral treatment. Also, patients who are non-immune to varicella zoster virus should be informed about the availability of postexposure prophylaxis should they have contact with this pathogen. Prophylaxis against Pneumocystis jirovecii seems to be beneficial in patients treated with daily doses >15-30 mg of prednisolone or equivalent for >2-4 weeks. Conclusions: These recommendations provide guidance on the screening and prevention of chronic and opportunistic infections. Their adoption in clinical practice is recommended to standardise and optimise care to reduce the burden of opportunistic infections in people living with AIIRD.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Antirheumatic Agents
- Autoimmune Diseases
- Tuberculosis
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- art (ämneskategori)
- ref (ämneskategori)
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Fragoulis, Georg ...
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Nikiphorou, Elen ...
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Dey, Mrinalini
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Zhao, Sizheng St ...
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Courvoisier, Del ...
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Arnaud, Laurent
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Atzeni, Fabiola
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Behrens, Georg M ...
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Bijlsma, Johanne ...
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Böhm, Peter
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Constantinou, Co ...
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Garcia-Diaz, Sil ...
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Kapetanovic, Mel ...
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Lauper, Kim
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Luís, Mariana
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Morel, Jacques
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Nagy, György
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Poleverino, Eva
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Van Rompay, Jef
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Sebastiani, Marc ...
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Strangfeld, Anja
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De Thurah, Annet ...
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Galloway, James
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Hyrich, Kimme L.
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