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Sökning: WFRF:(D'hooge P) > (2006-2009)

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  • Larsson, Matilda, 1981-, et al. (författare)
  • Ultrasound-based 2D Strain Estimation of the Carotid Artery : an in-silico feasibility study
  • 2009
  • Ingår i: Ultrasonics Symposium (IUS), 2009 IEEE International. - : IEEE. - 9781424443895 ; , s. 5441992-
  • Konferensbidrag (refereegranskat)abstract
    • Ultrasound based estimation of arterial wall properties is commonly used to assess vessel wall stiffness in studies of vascular diseases. Recently, it was shown that the longitudinal motion of the vessel during systole can be measured using speckle tracking. However, the assessment of longitudinal strain in the vessel wall has to be further investigated. The aim of this study was to test the feasibility of simultaneous assessment of radial and longitudinal strain in the carotid artery using computer simulations. A kinematic cylindrical model of the carotid artery with realistic dimensions was constructed. The model was deformed radially according to temporal distention measured in-vivo while longitudinal deformation was the result of conservation of volume. Moreover, longitudinal motion was superimposed based on profiles obtained in-vivo. Ultrasound long axis images were simulated using a generalized convolution model (COLE) with realistic image properties. Four models with different scatterer distributions were built. For each of them, longitudinal and radial motion were estimated using normalized cross-correlation with spline interpolation to detect sub-sample motion. Radial and longitudinal strains, obtained by linear regression were compared with the ground truth from the model. The maximal systolic radial strain was estimated to be -12.77 ± 0.4% (ground truth -13.89%) while longitudinal strain was 5.21 ± 0.67% (ground truth 5.3%). This study shows the feasibility of simultaneously measuring radial and longitudinal strain in the carotid artery by making use of currently available hardware.
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