| 1. |
- Dahlgren, Curt, et al.
(författare)
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Dödens semiotik : gravstenen som odödlighetens medium
- 2002
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Ingår i: Religion och sociologi : ett fruktbart möte : festskrift till Göran Gustafsson. - 0280-5723. ; , s. 97-110
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Allt fler gravstenar har enbart namn och födelsedata. Likaså minskar antalet gravar med yrkesangivelse. Antalet gravstenar med blommor, fåglar och naturscenerier ökar. Huruvida dessa skall ses som en beskrivning av individen är osäkert, men i vissa fall är det uppenbart, t ex när tecknet utgörs av en hund eller en tydlig yrkessymbol. Liksom i dödsannonserna kan man förvänta sig att också gravstenar kommer att ge antydningar om vem den döda var. På så sätt ökar chansen till odödlighet. Detta kan då antingen göras genom indicier eller genom ikoner, dvs. ett foto av den avlidna. Av de gravstenar som presenterats här kan enbart ett fåtal med säkerhet påstås vara ikoner eller indicier. Förmodligen kommer dessa att bli vanligare i framtiden. Så finns t ex två gravstenar på Västra kyrkogården i Halmstad där den ena har dels en färgbild av den avlidna svenska kvinnan, dels en flygande kolibri som suger nektar ur en blomma. Dessutom sitter en liten groda ovanpå naturstenen. Den andra stenen är rest över en invandrad och har dels en fjäril, dels ett kors, vilka båda är kristna tecken. Över korset finns ett fiskespö med en krokad fisk. Enligt min mening visar dessa tydligt på strävan efter odödlighet. Aven om jag kommer tillbaka om 20 år så vet jag hur kvinnan såg ut utan att någonsin ha träffat henne. Likaså vet jag att den invandrade mannen tyckte om att fiska, och kanske också var troende kristen.
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| 2. |
- Hamberg, Eva, et al.
(författare)
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Utbud och efterfrågan på religiösa "marknader"
- 2002
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Ingår i: Religion och sociologi : ett fruktbart möte : festskrift till Göran Gustafsson (Religio, ISSN: 0280-5723 ; 55). - 0280-5723.
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 3. |
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| 4. |
- Dahlgren, Jovanna, 1964, et al.
(författare)
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Prenatal cytokine exposure results in obesity and gender-specific programming.
- 2001
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Ingår i: American journal of physiology. Endocrinology and metabolism. - 0193-1849. ; 281:2
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Tidskriftsartikel (refereegranskat)abstract
- Prenatal events appear to program hormonal homeostasis, contributing to the development of somatic disorders at an adult age. The aim of this study was to examine whether maternal exposure to cytokines or to dexamethasone (Dxm) would be followed by hormonal consequences in the offspring at adult age. Pregnant rats were injected on days 8, 10, and 12 of gestation with either human interleukin-6 (IL-6) or tumor necrosis factor-alpha (TNF-alpha) or with Dxm. Control dams were injected with vehicle. All exposed offspring developed increased body weight (P < 0.05--0.001), apparently due to an increase of 30--40% in adipose tissue weight (P < 0.05--0.01). Corticosterone response to stress was increased in the IL-6 group (P < 0.05-0.01). Dxm-treated male rats exhibited blunted Dexamethasone suppression test results. In male rats, insulin sensitivity was decreased after IL-6 exposure (P < 0.01), whereas basal insulin was elevated in the TNF-alpha group (P < 0.01). In female rats, plasma testosterone levels were higher in all exposed groups compared with controls (P < 0.01--0.001), with the exception of Dxm-exposed offspring. Males in the TNF-alpha group showed decreased locomotor activity (P < 0.05), and females in the IL-6 group showed increased locomotor activity (P < 0.05). These results indicate that prenatal exposure to cytokines or Dxm leads to increased fat depots in both genders. In females, cytokine exposure was followed by a state of hyperandrogenicity. The results suggest that prenatal exposure to cytokines or Dxm can induce gender-specific programming of neuroendocrine regulation with consequences in adult life.
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| 5. |
- Dahlgren, Liselotte, et al.
(författare)
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Human papillomavirus is more common in base of tongue than in mobile tongue cancer and is a favorable prognostic factor in base of tongue cancer patients.
- 2004
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Ingår i: International Journal of Cancer. - : Wiley. - 0020-7136 .- 1097-0215. ; 112:6, s. 1015-9
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Tidskriftsartikel (refereegranskat)abstract
- The frequency of human papilloma virus (HPV) and its influence on clinical outcome was analyzed retrospectively in pre-treatment paraffin embedded biopsies from 110 patients with tongue cancer. The presence of HPV DNA was examined in 85 mobile tongue tumors and 25 base of tongue tumors by a polymerase chain reaction (PCR) with 2 general primer pairs, GP5+/6+ and CPI/IIG. When HPV-DNA was found, HPV-type specific primers and direct sequencing were used for HPV sub-type verification. Twelve of 110 (10.9%) samples were HPV-positive; 9 for HPV-16, 1 for HPV-33, 1 for HPV-35 and 1 could not be analyzed because of shortage of DNA. HPV was significantly more common in base of tongue tumors (10/25, 40.0%) compared to tumors of the mobile tongue (2/85, 2.3%). The influence of HPV on clinical outcome in mobile tongue cancer could not be studied, due to that HPV was present in too few cases. Of the 19 patients with base of tongue cancer that were included in the survival analysis, however, 7 patients with HPV-positive base of tongue cancer had a significantly favorable 5-year survival rate compared to the 12 HPV-negative patients. In conclusion, HPV is significantly more common in base of tongue cancer than in mobile tongue cancer, and has a positive impact on disease-specific survival in patients with base of tongue cancer.
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| 6. |
- Dahlstrand, Hanna, et al.
(författare)
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Presence of human papillomavirus in tonsillar cancer is a favourable prognostic factor for clinical outcome.
- 2004
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Ingår i: Anticancer Research. - 0250-7005 .- 1791-7530. ; 24:3b, s. 1829-35
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of this article is to review the current knowledge on the status and significance of human papillomavirus (HPV) in tonsillar cancer. Current data in scientific reports and data from the Karolinska Hospital and Karolinska Institute, Sweden, demonstrate that approximately half of all tonsillar cancer is HPV-positive. Moreover, patients with HPV-positive cancer have a lower risk of relapse and longer survival compared to patients with HPV-negative tonsillar cancer. The favourable outcome for patients harbouring HPV-positive tonsillar cancer cannot be attributed to increased radiosensitivity, since there is no significant difference in sensitivity to radiotherapy between HPV-positive and -negative tonsillar cancer. However, HPV-positive cancer exhibits less genetic instability i.e. shows a lower degree of aneuploidy and a tendency to have fewer chromosomal aberrations, when compared to HPV-negative tonsillar cancer.
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| 7. |
- Engquist, Bo, et al.
(författare)
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Marginal bone reaction to oral implants : A prospective comparative study of Astra Tech and Brσnemark System implants
- 2002
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Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 13:1, s. 30-37
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Tidskriftsartikel (refereegranskat)abstract
- In earlier studies of Astra Tech and Brσnemark System implants, high survival rates and small marginal bone changes have been demonstrated. The aim of this study was to compare the two systems, primarily with regard to marginal bone changes, but also with regard to other clinical variables of interest. The present paper describes the results after three years. Sixty-six patients were included in the study and randomly assigned to treatment with Astra Tech implants (n = 184) or Brσnemark System implants (n = 187). The marginal bone level was radiographically examined at fixture insertion, at abutment connection, at baseline (delivery of the prosthetic construction) and at 1- and 3-year follow-up examinations. Between fixture insertion and the baseline examination, the pattern of marginal bone resorption differed between the two systems. However, there was no significant marginal bone change between baseline and the 1-year examination or between the 1- and 3-year examinations. Nor were there any differences between the systems. The mean bone loss in the upper jaw between BL (baseline) and 3 years was 0.2▒0.3 mm for Astra Tech implants and 0.2▒0.1 mm for Brσnemark System implants. The corresponding figures for the lower jaw were 0.3▒0.2 mm and 0.2▒0.1 mm. The survival rate of Astra Tech implants was significantly higher (98.9%) than for Brσnemark System implants (95.2%). However, five of the nine implant losses in the Brσnemark group occurred in one patient. For that reason, this result must be interpreted with caution. The number of patients with implant losses did not differ significantly between the systems. Few complications were recorded up to 3 years.
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| 8. |
- Engquist, Bo, et al.
(författare)
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Simplified methods of implant treatment in the edentulous lower jaw. A controlled prospective study. Part I : one-stage versus two-stage surgery.
- 2002
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Ingår i: Clinical Implant Dentistry and Related Research. - 1523-0899 .- 1708-8208. ; 4:2, s. 93-103
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The original protocol for Brσnemark System implants in the mandible was a two-stage procedure with 3 months healing time. With five or six implants and a cast framework of gold, the treatment is rather expensive, and simplified methods would be desirable. PURPOSE: The goal of this controlled serial study was to investigate the outcome of a simplified procedure with one-stage surgery, four Brσnemark implants, shortened healing time, and a new titanium-acrylic fixed full prosthesis. MATERIALS AND METHODS: Eighty-two patients were treated in three different groups at two specialist centers. All patients were provided with four implants, loaded with a Procera All-in-One bridge (Nobel Biocare, Gothenburg, Sweden) after 12 weeks. In group A (n = 30), one-stage surgery was combined with two-piece implants. In group B (n = 30), the control group, two-stage surgery and two-piece implants were used. In group C (n = 22), one-stage surgery was combined with one-piece implants. Marginal bone level was rated from radiographs at implant insertion, at baseline, and after 1 year. RESULTS: The survival rate after 1 year for group A was 93.3%, group B, 97.5%, and group C, 93.2%. The differences were not statistically significant. Between fixture insertion and baseline, the average bone loss for group A was 1.2 mm, group B, 1.3 mm, and group C, 1.3 mm. No complications in the form of bridge loosening or acrylic fractures were recorded during the first year. CONCLUSIONS: The survival rates and the marginal bone changes did not differ significantly between the one-stage groups and the control group. The survival rate and the marginal bone changes were similar for one-piece and two-piece implants. Four implants were sufficient to support full fixed prostheses in the mandibles. The Procera All-in-One bridges proved to be of high quality, and no complications were experienced. key words: endosseous implants, nonsubmerged implants, one-piece implants, prospective clinical study, submerged implants
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| 9. |
- Engquist, Bo, et al.
(författare)
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Simplified methods of implant treatment in the edentulous lower jaw. Part II : Early loading
- 2004
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Ingår i: Clinical Implant Dentistry and Related Research. - 1523-0899 .- 1708-8208. ; 6:2, s. 90-100
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Tidskriftsartikel (refereegranskat)abstract
- Background: Most implant treatment is performed with a two-stage surgical procedure. A disadvantage of these implant treatments is that they are time-consuming. Purpose: The aim of the present study was to evaluate the results of early loading in the edentulous mandible and to compare those results with treatment results of one-stage surgery followed by a healing period and with two-stage surgery. Material and Methods: The material comprises four treatment groups with a total of 108 patients with edentulous lower jaws and 432 implants. All patients were treated with Brånemark implants (Nobel Biocare AB, Gothenburg, Sweden) with a turned surface and fixed prostheses in the lower jaw, supported by four implants. The patients in group A were treated with a one-stage procedure, a two-piece implant, and a 3-month healing period before loading. Group B (control group) had a two-stage procedure, a two-piece implant, and a 3-month healing period. Group C had a one-stage procedure, a one-piece implant, and a 3-month healing period. Group D was treated with a one-stage surgical procedure, a two-piece implant, and early loading (within 3 weeks). All patients were provided with a Procera® Implant Bridge (Nobel Biocare) with a framework made by computer-assisted milling of one piece of pure titanium. All patients have been followed up for 1 year. Results: The survival rates were 93.2 to 93.3% in the experimental groups and 97.5% in the control group. The difference was not statistically significant. The measurements of the marginal bone level demonstrated a mean bone loss of 0.8 mm between fixture insertion and the 1-year examination in patients with early loading (group D) whereas the bone loss in patients who underwent a healing period before loading was 1.3 to 1.6 mm. The difference between the control group and the group with early loading was significant. Conclusions: Survival rates for patients treated with a one-stage procedure were lower than survival rates for patients treated according to a "classical concept," but the differences were not statistically significant. There was no difference between treatment results with one-piece and two-piece implants. The implant loss in patients with early loading was probably caused by overloading, and careful supervision of occlusal loading is recommended. Early loading gave significantly less marginal bone loss when compared with two-stage surgery.
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| 10. |
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