| 1. |
- Dai, X W, et al.
(författare)
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Pyrolysis of waste tires in a circulating fluidized-bed reactor
- 2001
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Ingår i: Energy. - 0360-5442 .- 1873-6785. ; 26:4, s. 385-399
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Tidskriftsartikel (refereegranskat)abstract
- Using a circulating fluidized bed (CFB) as the main reactor, an integrated process development unit was operated aiming at the pyrolysis of waste tires. The main chemical processes in the CFB can be divided into two zones corresponding to pyrolysis and secondary reactions. The pyrolysis of tire powder was carried out at various pyrolysis temperatures, particle sizes of tire powder and feed positions. The effects of temperature, residence time and heating rate on pyrolysis were analyzed based on the experimental data. The main trends are that (1) a long residence time contributes to secondary reactions and (2) lower temperature and heating rate favor carbonization, which reduces the oil yield. Analysis of the pyrolytic oil shows that the predominant components are aromatics, followed by alkanes, non-hydrocarbons and asphalt.
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| 2. |
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| 3. |
- Dai, Y, et al.
(författare)
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Analysis of an interferon-gamma gene dinucleotide-repeat polymorphism in Nordic multiple sclerosis patients
- 2001
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Ingår i: Multiple sclerosis (Houndmills, Basingstoke, England). - : SAGE Publications. - 1352-4585 .- 1477-0970. ; 7:3, s. 157-163
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Tidskriftsartikel (refereegranskat)abstract
- The proinflammatory cytokine interferon (IFN)-γ has been shown to influence the course of multiple sclerosis (MS). The IFN-γ (IFNG) contains a multiallelic dinucleotide repeat in intron l. To investigate whether alleles at this locus influence susceptibility to MS, we performed linkage and familial association analyses on 100 sibling pairs from four Nordic countries, and case-control association analysis on 220 intermediately disabled sporadic MS patients and 266 controls. To determine the effect of the polymorphism on disease outcome, we compared genotype frequencies in the most and least disabled octiles of a total cohort of 913 cases. We also measured IFN-γ mRNA levels in unstimulated peripheral blood mononuclear cells from 46 MS patients and 27 controls grouped according to IFNG intron l genotype. Both nonparametric linkage analysis and transmission disequilibrium testing of the 100 sibling pairs produced negative results. Genotype frequencies for intermediate-MS patients did not differ significantly from those for controls; nor did genotype frequencies in the benign-MS octile differ significantly from those in the severe-MS octile. Comparison of IFN-γ mRNA levels in genotype-conditioned subgroups revealed no significant differences. Thus, alleles at the IFNG intron l dinucleotide repeat appear to affect neither MS susceptibility and severity nor IFN-γ mRNA expression in vivo.
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| 5. |
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| 6. |
- MacDonald, Patrick, et al.
(författare)
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Impaired glucose-stimulated insulin secretion, enhanced IP insulin tolerance and increased {beta}-cell mass in mice lacking the p110{gamma} isoform of PI3-kinase.
- 2004
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Ingår i: Endocrinology. - : The Endocrine Society. - 0013-7227 .- 1945-7170. ; 145:9, s. 4078-4083
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Tidskriftsartikel (refereegranskat)abstract
- Phosphoinositide 3-kinase (PI3 kinase) has been implicated in G protein-coupled receptor regulation of pancreatic ß-cell growth and glucose-stimulated insulin secretion. The G protein-activated p110{gamma} isoform of PI3 kinase was detected in insulinoma cells, mouse islets, and human islets. In 7- to 10-wk-old mice, knockout of p110{gamma} reduced the plasma insulin response to ip glucose injection and impaired first and second phase glucose-stimulated insulin secretion from pancreata perfused ex vivo. The p110{gamma} –/– mice responded to preinjection with the glucagon-like peptide-1 receptor agonist exendin 4, such that plasma glucose and insulin responses to ip glucose injection were not different from wild types. Mice lacking p110{gamma} were not diabetic and were only slightly glucose intolerant (ip glucose injection) compared with wild types, in part due to enhanced responsiveness to insulin as determined by an ip insulin tolerance test. Despite severely reduced insulin secretion in these animals, the p110{gamma} –/– mice had greater pancreatic insulin content, and an increased ß-cell mass due to ß-cell hypertrophy. These surprising results suggest that the G protein-coupled p110{gamma} isoform of PI3 kinase is not central to the development or maintenance of sufficient ß-cell mass but positively regulates glucose-stimulated insulin secretion.
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| 7. |
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| 8. |
- Zhang, Z. G, et al.
(författare)
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Radiative properties of EuII and EuIII obtained from lifetime and branching ratio measurements
- 2000
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Ingår i: Journal of Physics B: Atomic, Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 33:3, s. 521-526
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Tidskriftsartikel (refereegranskat)abstract
- Radiative lifetimes of nine levels in Eu II (4f(7)6p, 4f(6)5d6s and 4f(6)5d(2)) and Eu III (4f(6)5d) have been measured using time-resolved laser-induced fluorescence spectroscopy on a laser-produced europium plasma. Oscillator strengths for a number of Eu II lines have been derived by combining the lifetimes with branching ratios measured in the emission spectrum of a hollow-cathode lamp.
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