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- Narri, Vandana, et al.
(författare)
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Set-Membership Estimation in Shared Situational Awareness for Automated Vehicles in Occluded Scenarios
- 2021
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Ingår i: 2021 32nd IEEE Intelligent Vehicles Symposium (IV). - : Institute of Electrical and Electronics Engineers (IEEE). ; , s. 385-392
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Konferensbidrag (refereegranskat)abstract
- One of the main challenges in developing autonomous transport systems based on connected and automated vehicles is the comprehension and understanding of the environment around each vehicle. In many situations, the understanding is limited to the information gathered by the sensors mounted on the ego-vehicle, and it might be severely affected by occlusion caused by other vehicles or fixed obstacles along the road. Situational awareness is the ability to perceive and comprehend a traffic situation and to predict the intent of vehicles and road users in the surrounding of the ego-vehicle. The main objective of this paper is to propose a framework for how to automatically increase the situational awareness for an automatic bus in a realistic scenario when a pedestrian behind a parked truck might decide to walk across the road. Depending on the ego-vehicle's ability to fuse information from sensors in other vehicles or in the infrastructure, shared situational awareness is developed using a set-based estimation technique that provides robust guarantees for the location of the pedestrian. A two-level information fusion architecture is adopted, where sensor measurements are fused locally, and then the corresponding estimates are shared between vehicles and units in the infrastructure. Thanks to the provided safety guarantees, it is possible to adjust the ego-vehicle speed appropriately to maintain a proper safety margin. Three scenarios of growing information complexity are considered throughout the study. Simulations show how the increased situational awareness allows the ego-vehicle to maintain a reasonable speed without sacrificing safety.
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| 2. |
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| 3. |
- Purnomo, Victor, 1992, et al.
(författare)
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New approach for particle size and shape analysis of iron-based oxygen carriers at different oxidation degrees
- 2024
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Ingår i: Particuology. - : Elsevier. - 2210-4291 .- 1674-2001. ; 90, s. 493-503
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Tidskriftsartikel (refereegranskat)abstract
- One of the crucial issues in the chemical looping technology lies in its bed material: the oxygen carrier. Particle size analysis of an oxygen carrier is important since in a fluidized bed the material can only work well within a specific size range. While the favorable size ranges for oxygen carrier materials have already been reported, none of the published studies has analyzed the particle size and shape of oxygen carriers in detail. Furthermore, the effect of oxygen carriers’ oxidation degree on such properties has not been considered either. This study aimed to report the particle size and shape analysis of five iron-based oxygen carriers, one natural ore, one synthetic material, and three residue products, at different oxidation degrees using dynamic image analysis (DIA). The oxygen carriers were prepared at different mass conversion degrees in a fluidized bed batch reactor. The size distribution, sphericity, and aspect ratio of the oxygen carrier particles were examined experimentally using a Camsizer instrument. Our results show that the DIA method was successfully able to analyze the particle size and shape of our oxygen carriers with satisfying accuracy for comparison. The oxidation state of the investigated materials seems to only affect the particle size and shape of oxygen carriers to a minor extent. However, exposures to redox cycles in a fluidized bed reactor may alter the particle size and shape of most oxygen carriers.
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| 4. |
- Siegele, Bradford J., et al.
(författare)
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N-terminus DUX4-immunohistochemistry is a reliable methodology for the diagnosis of DUX4-fused B-lymphoblastic leukemia/lymphoma (N-terminus DUX4 IHC for DUX4-fused B-ALL)
- 2022
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Ingår i: Genes Chromosomes and Cancer. - : Wiley. - 1045-2257 .- 1098-2264. ; 61:8, s. 449-458
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Tidskriftsartikel (refereegranskat)abstract
- B-lymphoblastic leukemia/lymphoma (B-ALL) is the most common pediatric malignancy and the most commonly diagnosed adult lymphoblastic leukemia. Recent advances have broadened the spectrum of B-ALL, with DUX4 gene fusions implicated in a subclass occurring in adolescents and young adults and harboring a favorable prognosis. DUX4 fusions have been challenging to identify. We aimed to determine whether expression of the DUX4 oncoprotein, as detected by targeted immunohistochemistry, might serve as a surrogate for molecular detection of DUX4 fusions in B-ALL. A cohort of investigational B-ALLs was generated with enrichment for DUX4 fusions by the inclusion of cases with characteristic demographic features and immunophenotypic properties. B-ALLs with mutually exclusive cytogenetics were collected. Immunohistochemical staining by a monoclonal antibody raised against the N-terminus of the DUX4 protein was performed. N-DUX4 immunohistochemistry demonstrated strong, crisp nuclear staining in blasts of seven investigational cases, six of which had nucleic acid material available for molecular evaluation. Five of these cases demonstrated RNA-seq DUX4-fusion positivity. One N-DUX4 immunohistochemistry positive case lacked a definitive DUX4-fusion by RNA-seq, though demonstrated a gene expression profile characteristic of DUX4-rearranged B-ALLs, a CD2+ immunophenotype, and a lack of staining by C-terminus DUX4 antibody immunohistochemistry. At least 83.3% [5/6] positive predictive value. N-DUX4 immunohistochemistry was negative in blasts of three RNA-seq DUX4-fusion-negative cases (3/3; 100% negative predictive value). B-ALLs with mutually exclusive cytogenetic profiles were all N-DUX4 negative (0/10, specificity 100%). N-DUX4 immunohistochemistry is reliable for the distinction of DUX4-rearranged B-ALLs from other B-ALLs. We recommend its use for subclassification of B-ALLs in adolescents and young adults and in B-ALLs that remain “not otherwise specified.”.
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