Sökning: WFRF:(Debeaufort Carine E.)
> (2019) >
Trends and cyclical...
Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25year period 1989-2013 : a multicentre prospective registration study
-
Patterson, Christopher C. (författare)
-
Harjutsalo, Valma (författare)
-
Rosenbauer, Joachim (författare)
-
visa fler...
-
Neu, Andreas (författare)
-
Cinek, Ondrej (författare)
-
Skrivarhaug, Torild (författare)
-
Rami-Merhar, Birgit (författare)
-
Soltesz, Gyula (författare)
-
Svensson, Jannet (författare)
-
Parslow, Roger C. (författare)
-
Castell, Conxa (författare)
-
Schoenle, Eugen J. (författare)
-
Bingley, Polly J. (författare)
-
- Dahlquist, Gisela (författare)
- Umeå universitet,Pediatrik
-
Jarosz-Chobot, Przemyslawa K. (författare)
-
Marciulionyte, Dale (författare)
-
Roche, Edna F. (författare)
-
Rothe, Ulrike (författare)
-
Bratina, Natasa (författare)
-
Ionescu-Tirgoviste, Constantin (författare)
-
Weets, Ilse (författare)
-
Kocova, Mirjana (författare)
-
Cherubini, Valentino (författare)
-
Putarek, Natasa Rojnic (författare)
-
Debeaufort, Carine E. (författare)
-
Samardzic, Mira (författare)
-
Green, Anders (författare)
-
visa färre...
-
(creator_code:org_t)
- 2018-11-28
- 2019
- Engelska.
-
Ingår i: Diabetologia. - : Springer. - 0012-186X .- 1432-0428. ; 62:3, s. 408-417
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://umu.diva-por... (primary) (Raw object)
-
https://link.springe...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Aims/hypothesis: Against a background of a near-universally increasing incidence of childhood type 1 diabetes, recent reports from some countries suggest a slowing in this increase. Occasional reports also describe cyclical variations in incidence, with periodicities of between 4 and 6years.Methods: Age/sex-standardised incidence rates for the 0- to 14-year-old age group are reported for 26 European centres (representing 22 countries) that have registered newly diagnosed individuals in geographically defined regions for up to 25years during the period 1989-2013. Poisson regression was used to estimate rates of increase and test for cyclical patterns. Joinpoint regression software was used to fit segmented log-linear relationships to incidence trends.Results: Significant increases in incidence were noted in all but two small centres, with a maximum rate of increase of 6.6% per annum in a Polish centre. Several centres in high-incidence countries showed reducing rates of increase in more recent years. Despite this, a pooled analysis across all centres revealed a 3.4% (95% CI 2.8%, 3.9%) per annum increase in incidence rate, although there was some suggestion of a reduced rate of increase in the 2004-2008 period. Rates of increase were similar in boys and girls in the 0- to 4-year-old age group (3.7% and 3.7% per annum, respectively) and in the 5- to 9-year-old age group (3.4% and 3.7% per annum, respectively), but were higher in boys than girls in the 10- to 14-year-old age group (3.3% and 2.6% per annum, respectively). Significant 4year periodicity was detected in four centres, with three centres showing that the most recent peak in fitted rates occurred in 2012.Conclusions/interpretation: Despite reductions in the rate of increase in some high-risk countries, the pooled estimate across centres continues to show a 3.4% increase per annum in incidence rate, suggesting a doubling in incidence rate within approximately 20years in Europe. Although four centres showed support for a cyclical pattern of incidence with a 4year periodicity, no plausible explanation for this can be given.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Nyckelord
- Cyclical variation
- Epidemiology
- Incidence
- Temporal change
- Type 1 diabetes mellitus
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Patterson, Chris ...
-
Harjutsalo, Valm ...
-
Rosenbauer, Joac ...
-
Neu, Andreas
-
Cinek, Ondrej
-
Skrivarhaug, Tor ...
-
visa fler...
-
Rami-Merhar, Bir ...
-
Soltesz, Gyula
-
Svensson, Jannet
-
Parslow, Roger C ...
-
Castell, Conxa
-
Schoenle, Eugen ...
-
Bingley, Polly J ...
-
Dahlquist, Gisel ...
-
Jarosz-Chobot, P ...
-
Marciulionyte, D ...
-
Roche, Edna F.
-
Rothe, Ulrike
-
Bratina, Natasa
-
Ionescu-Tirgovis ...
-
Weets, Ilse
-
Kocova, Mirjana
-
Cherubini, Valen ...
-
Putarek, Natasa ...
-
Debeaufort, Cari ...
-
Samardzic, Mira
-
Green, Anders
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Endokrinologi oc ...
- Artiklar i publikationen
-
Diabetologia
- Av lärosätet
-
Umeå universitet