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Increased risk of stroke with darbepoetin alfa in anaemic heart failure patients with diabetes and chronic kidney disease.

Bello, Natalie A (author)
Lewis, Eldrin F (author)
Desai, Akshay S (author)
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Anand, Inder S (author)
Krum, Henry (author)
McMurray, John J V (author)
Olson, Kurt (author)
Solomon, Scott D (author)
Swedberg, Karl, 1944 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
van Veldhuisen, Dirk J (author)
Young, James B (author)
Pfeffer, Marc A (author)
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 (creator_code:org_t)
2015-10-01
2015
English.
In: European journal of heart failure. - : Wiley. - 1879-0844 .- 1388-9842. ; 17:11, s. 1201-1207
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The use of an erythropoesis-stimulating agent, darbepoetin alfa (DA), to treat anaemia in patients with diabetes mellitus and chronic kidney disease was associated with a heightened risk of stroke and neutral efficacy in the Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT), despite epidemiological data suggesting the contrary. However, this association has not been evaluated in another randomized, placebo-controlled trial.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

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