| 1. |
- Nowak-Sliwinska, Patrycja, et al.
(författare)
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Consensus guidelines for the use and interpretation of angiogenesis assays
- 2018
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Ingår i: Angiogenesis. - : Springer. - 0969-6970 .- 1573-7209. ; 21:3, s. 425-532
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Forskningsöversikt (refereegranskat)abstract
- The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitations. This article describes in vivo, ex vivo, and in vitro bioassays that are available for the evaluation of angiogenesis and highlights critical aspects that are relevant for their execution and proper interpretation. As such, this collaborative work is the first edition of consensus guidelines on angiogenesis bioassays to serve for current and future reference.
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| 2. |
- Ogren, J, et al.
(författare)
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Prevalence of Dientamoeba fragilis, Giardia duodenalis, Entamoeba histolytica/dispar, and Cryptosporidium spp in Da Nang, Vietnam, detected by a multiplex real-time PCR
- 2016
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Ingår i: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. - 1600-0463. ; 124:6, s. 529-533
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Tidskriftsartikel (refereegranskat)
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| 3. |
- Dimberg, Peter H., 1985-, et al.
(författare)
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A Comparison Between Regression Models and Genetic Programming for Predictions of Chlorophyll-a Concentrations in Northern Lakes
- 2016
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Ingår i: Environmental Modelling and Assessment. - : Springer Science and Business Media LLC. - 1420-2026 .- 1573-2967. ; 21:2, s. 221-232
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Tidskriftsartikel (refereegranskat)abstract
- Chlorophyll-a (chl-a) concentrations are often used as a proxy for water quality problems as well as phytoplankton blooms. Available chl-a models range from simple phosphorus loading models to complex regression and dynamic models. A comparison of multiple regression models was made with genetic programming (GP) techniques to predict chl-a concentrations over a large range of 104 Swedish lakes. Independent variables used were lake area, mean depth, iron, latitude, ammonium, nitrogen + nitrate, pH, phosphate, secchi depth, silicon, temperature, total phosphorus, total nitrogen and total organic carbon. GP is a method based on the Darwinian evolution theory. This implies that a program will be able to test different mathematical equations, iterating and improving each equation using fundamental ideas from evolution theory to increase the predictive power. A good correspondence was found between the multiple regression and the GP modelling approach. No significant improvement of the predictive power was found using GP, and it is therefore recommended that multiple regression methods should be preferred when predicting chl-a concentrations as these models tend to be less complex and the modelling approach is easier to use. Results from GP were in some cases more accurate compared to multiple regressions; however, the best model was created by multiple regressions which used concentrations of total phosphorus, total nitrogen and latitude as independent variables. These findings will be an important note for limnologists and modelling managers when developing future models of chl-a concentrations in lakes.
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| 4. |
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| 5. |
- Song, Nguyen Van, et al.
(författare)
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Prevalence of cervical infection and genotype distribution of human Papilloma virus among females in Da Nang, Vietnam
- 2017
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Ingår i: Anticancer Research. - : International Institute of Anticancer Research. - 0250-7005 .- 1791-7530. ; 37:3, s. 1243-1247
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Tidskriftsartikel (refereegranskat)abstract
- Aim: The goal of the present study was to determine the prevalence and distribution of high-risk human papilloma virus (HPV) genotypes in women from two districts in and around Da Nang city, Vietnam.Materials and Methods: All participants were randomly selected, 200 from the Hai Chau district and 200 from the Son Tra district. The detection and genotyping of HPV were performed by real-time polymerase chain reaction (PCR) technique.Results: Out of a total of 400 women, we found that 38 (9.5%) were infected with a high-risk HPV genotype, the most prevalent genotypes being 16, 18, 58 and 59. By assessment of the HPV findings in relation to sociodemographic characteristics, we found significant differences between the two study districts and between the age groups, as well as differences associated with occupation and the use of contraceptives.Conclusion: The proportion of high–risk genotypes other than 16 and 18 was relatively high, and since the HPV genotype distribution is known to vary greatly across populations, the information from this study can be used for planning of screening and vaccination programs in Da Nang.
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