| 1. |
- Ding, Huaiyi, et al.
(författare)
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Maximizing Integrated Optical and Electrical Properties of a Single ZnO Nanowire through Native Interfacial Doping
- 2014
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Ingår i: Advanced Materials. - : Wiley. - 0935-9648 .- 1521-4095. ; 26:19, s. 3035-3041
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Tidskriftsartikel (refereegranskat)abstract
- A native interfacial doping layer introduced in core-shell type ZnO nanowires by a simple vapor phase re-growth procedure endows the produced nanowires with both excellent electrical and optical performances compared to conventional homogeneous ZnO nanowires. The unique Zn-rich interfacial structure in the core-shell nanowires plays a crucial role in the outstanding performances.
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| 2. |
- Jacobs, Kevin B, et al.
(författare)
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Detectable clonal mosaicism and its relationship to aging and cancer.
- 2012
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Ingår i: Nature Genetics. - New York : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 44:6, s. 651-658
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Tidskriftsartikel (refereegranskat)abstract
- In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, we observed large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples. We observed mosaic abnormalities, either aneuploidy or copy-neutral loss of heterozygosity, of >2 Mb in size in autosomes of 517 individuals (0.89%), with abnormal cell proportions of between 7% and 95%. In cancer-free individuals, frequency increased with age, from 0.23% under 50 years to 1.91% between 75 and 79 years (P = 4.8 × 10(-8)). Mosaic abnormalities were more frequent in individuals with solid tumors (0.97% versus 0.74% in cancer-free individuals; odds ratio (OR) = 1.25; P = 0.016), with stronger association with cases who had DNA collected before diagnosis or treatment (OR = 1.45; P = 0.0005). Detectable mosaicism was also more common in individuals for whom DNA was collected at least 1 year before diagnosis with leukemia compared to cancer-free individuals (OR = 35.4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases.
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| 3. |
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| 4. |
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| 5. |
- Wang, Hao, et al.
(författare)
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Minimum rate guaranteed call admission control for cumulative rate distribution based scheduling
- 2011
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Ingår i: IEEE Communications Letters. - 1089-7798 .- 1558-2558. ; 15:11, s. 1181-1183
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Tidskriftsartikel (refereegranskat)abstract
- In this letter, we investigate call admission control (CAC) for cumulative rate distribution based scheduling (CS) in wireless communication networks. We first analyze the multi-user diversity gain (MDG) of CS, which is applicable to general channel conditions. Then we propose the minimum rate guaranteed CS/ORR based CAC algorithm, COCAC, which jointly uses CS and opportunistic round robin (ORR) for resource prediction and CAC decision. Furthermore, we evaluate the performance of our COCAC algorithm through simulation. Results show that COCAC can significantly reduce the new call blocking rate, while strictly guarantee the minimum rate requirements of all serving users.
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| 6. |
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| 7. |
- Wang, Yutao, et al.
(författare)
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Strategic assessment of fuel taxation in energy conservation and CO2 reduction for road transportation: a case study from China
- 2013
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Ingår i: Stochastic Environmental Research and Risk Assessment. - : Springer Science and Business Media LLC. - 1436-3240 .- 1436-3259. ; 27:5, s. 1231-1238
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Tidskriftsartikel (refereegranskat)abstract
- Road transportation has attracted extensive attention throughout the world because of its high energy demands and numerous externalities. Sustainable road transportation has thus become a great challenge for politicians and decision-makers all over the world. There have been a series of studies indicating that appropriate pricing of fuel can be both effective and efficient for reducing overconsumption of transport fuel. However, relatively little research has been done on fuel price approaches in developing country contexts. For a country like China, where road traffic today is growing more than in other countries, there is a strategic interest to do more economic analyses of fair and efficient pricing of fuel. In this study, we present a strategic assessment of fuel pricing in energy conservation and CO2 reduction from road transportation in China, both in a retrospective and a prospective perspective. First of all, the correlation between fuel price and road transport gasoline demand, based upon data from 1995 to 2007, was examined with an econometric model. Secondly, on basis of the elasticity model, the potential reductions with respect to fuel demand and Green House Gas (GHG) emissions as a consequence of a strategic fuel tax implementation in China were examined up to 2030. The results indicate that such strategic fuel taxation can play a considerable role in steering the growth of road transport gasoline demand, and thus also Chinese GHG emissions.
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| 8. |
- Wang, Zhaoming, et al.
(författare)
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Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
- 2014
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Ingår i: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 23:24, s. 6616-6633
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Tidskriftsartikel (refereegranskat)abstract
- Genome-wide association studies (GWAS) have mapped risk alleles for at least 10 distinct cancers to a small region of 63 000 bp on chromosome 5p15.33. This region harbors the TERT and CLPTM1L genes; the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play a role in apoptosis. To investigate further the genetic architecture of common susceptibility alleles in this region, we conducted an agnostic subset-based meta-analysis (association analysis based on subsets) across six distinct cancers in 34 248 cases and 45 036 controls. Based on sequential conditional analysis, we identified as many as six independent risk loci marked by common single-nucleotide polymorphisms: five in the TERT gene (Region 1: rs7726159, P = 2.10 × 10(-39); Region 3: rs2853677, P = 3.30 × 10(-36) and PConditional = 2.36 × 10(-8); Region 4: rs2736098, P = 3.87 × 10(-12) and PConditional = 5.19 × 10(-6), Region 5: rs13172201, P = 0.041 and PConditional = 2.04 × 10(-6); and Region 6: rs10069690, P = 7.49 × 10(-15) and PConditional = 5.35 × 10(-7)) and one in the neighboring CLPTM1L gene (Region 2: rs451360; P = 1.90 × 10(-18) and PConditional = 7.06 × 10(-16)). Between three and five cancers mapped to each independent locus with both risk-enhancing and protective effects. Allele-specific effects on DNA methylation were seen for a subset of risk loci, indicating that methylation and subsequent effects on gene expression may contribute to the biology of risk variants on 5p15.33. Our results provide strong support for extensive pleiotropy across this region of 5p15.33, to an extent not previously observed in other cancer susceptibility loci.
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