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Intraductal papilla...
Intraductal papillary neoplasms of the bile duct: a European retrospective multicenter observational study (EUR-IPNB study)
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- Lluis, Nuria (författare)
- Miami Canc Inst, FL 33176 USA,Miami Cancer Institute at Baptist Health South Florida
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- Serradilla-Martin, Mario (författare)
- Miguel Servet Univ Hosp, Spain,Vall d'Hebron University Hospital
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- Achalandabaso, Mar (författare)
- Hosp Univ Vall dHebron, Spain,Vall d'Hebron University Hospital
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- Jehaes, Francois (författare)
- Univ Paris Cite, France,Beaujon Hospital,Université Paris Cité
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- Dasari, Bobby V. M. (författare)
- Queen Elizabeth Hosp, England,New Queen Elizabeth Hospital
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- Mambrilla-Herrero, Sara (författare)
- Cruces Univ Hosp, Spain,Hospital de Cruces
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- Sparrelid, Ernesto (författare)
- Karolinska Institutet
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- Balakrishnan, Anita (författare)
- Cambridge Univ Hosp NHS Fdn Trust, England; Univ Cambridge, England,Cambridge University Hospitals NHS Foundation Trust,University of Cambridge
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- Hoogwater, Frederik J. H. (författare)
- Univ Groningen, Netherlands,University Medical Center Groningen,University of Groningen
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- Amaral, Maria J. (författare)
- Ctr Hosp & Univ Coimbra, Portugal; Univ Coimbra, Portugal,University Hospital of Coimbra
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- Andersson, Bodil (författare)
- Lund University,Lunds universitet,Lever-, pankreas- och gallvägskirurgi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Hepato-Pancreato-Biliary Surgery,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
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- Berrevoet, Frederik (författare)
- Univ Hosp Gent, Belgium,Ghent University Hospital
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- Doussot, Alexandre (författare)
- CHU Besancon, France,Centre Hospitalier Universitaire de Besancon,Karolinska University Hospital
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- Lopez-Lopez, Victor (författare)
- Clin & Univ Hosp Virgen La Arrixaca, Spain,Hospital Virgen de la Arrixaca
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- Alsammani, Mohammedsuror (författare)
- Univ Witwatersrand, South Africa,University of the Witwatersrand
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- Detry, Olivier (författare)
- Univ Liege, Belgium,University of Liège Hospital
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- Domingo-del Pozo, Carlos (författare)
- Hosp Doctor Peset, Spain,Hospital Universitario Doctor Peset
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- Machairas, Nikolaos (författare)
- Natl & Kapodistrian Univ Athens, Greece,National and Kapodistrian University of Athens
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- Pekli, Damjan (författare)
- Semmelweis Univ, Hungary,Semmelweis University
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- Alcazar-Lopez, Candido F. (författare)
- Dr Balmis Gen Univ Hosp, Spain; Alicante Inst Hlth & Biomed Res ISABIAL, Spain,Alicante University General Hospital
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- Asbun, Horacio (författare)
- Miami Canc Inst, FL 33176 USA,Miami Cancer Institute at Baptist Health South Florida
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- Björnsson, Bergthor (författare)
- Linköping University,Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US,University of the Free State
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- Christophides, Thalis (författare)
- Nicosia Gen Hosp, Cyprus,Nicosia General Hospital
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- Diez-Caballero, Alberto (författare)
- Quirurg Cirujanos Asociados, Spain,Teknon Medical Center
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- Francart, David (författare)
- CHC Grp Sante, Belgium
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- Noel, Colin B. (författare)
- Univ Free State, South Africa
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- Sousa-Silva, Donzilia (författare)
- CHU Porto, Portugal,S. António General Hospital
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- Toledo-Martinez, Enrique (författare)
- Hosp Univ Marques de Valdecilla, Spain,Hospital Universitario Marqués de Valdecilla
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- Tzimas, George N. (författare)
- Hygeia Hosp, Greece,Hygeia Hospital
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- Yaqub, Sheraz (författare)
- Oslo Univ Hosp, Norway; Univ Oslo, Norway,University of Oslo,Oslo university hospital
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- Cauchy, Francois (författare)
- Univ Paris Cite, France,Université Paris Cité,Beaujon Hospital
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- Prieto-Calvo, Mikel (författare)
- Cruces Univ Hosp, Spain,Hospital de Cruces
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- DSouza, Melroy A. (författare)
- Karolinska Inst, Sweden
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- Spiers, Harry V. M. (författare)
- Cambridge Univ Hosp NHS Fdn Trust, England; Univ Cambridge, England,University of Cambridge,Cambridge University Hospitals NHS Foundation Trust
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- van den Heuvel, Marius C. (författare)
- Univ Groningen, Netherlands,University of Groningen,University Medical Center Groningen
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- Charco, Ramon (författare)
- Hosp Univ Vall dHebron, Spain,Vall d'Hebron University Hospital
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- Lesurtel, Mickael (författare)
- Univ Paris Cite, France,Université Paris Cité,Beaujon Hospital
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- Ramia, Jose M. (författare)
- Dr Balmis Gen Univ Hosp, Spain; Alicante Inst Hlth & Biomed Res ISABIAL, Spain; Miguel Hernandez Univ, Spain,Miguel Hernández University of Elche,Alicante University General Hospital
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(creator_code:org_t)
- LIPPINCOTT WILLIAMS & WILKINS, 2023
- 2023
- Engelska.
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Ingår i: International Journal of Surgery. - : LIPPINCOTT WILLIAMS & WILKINS. - 1743-9191 .- 1743-9159. ; 109:4, s. 760-771
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background/Purpose:Intraductal papillary neoplasm of the bile duct (IPNB) is a rare disease in Western countries. The main aim of this study was to characterize current surgical strategies and outcomes in the mainly European participating centers. Methods:A multi-institutional retrospective series of patients with a diagnosis of IPNB undergoing surgery between 1 January 2010 and 31 December 2020 was gathered under the auspices of the European-African Hepato-Pancreato-Biliary Association. The textbook outcome (TO) was defined as a non-prolonged length of hospital stay plus the absence of any Clavien-Dindo grade at least III complications, readmission, or mortality within 90 postoperative days. Results:A total of 28 centers contributed 85 patients who underwent surgery for IPNB. The median age was 66 years (55-72), 49.4% were women, and 87.1% were Caucasian. Open surgery was performed in 72 patients (84.7%) and laparoscopic in 13 (15.3%). TO was achieved in 54.1% of patients, reaching 63.8% after liver resection and 32.0% after pancreas resection. Median overall survival was 5.72 years, with 5-year overall survival of 63% (95% CI: 50-82). Overall survival was better in patients with Charlson comorbidity score 4 or less versus more than 4 (P=0.016), intrahepatic versus extrahepatic tumor (P=0.027), single versus multiple tumors (P=0.007), those who underwent hepatic versus pancreatic resection (P=0.017), or achieved versus failed TO (P=0.029). Multivariable Cox regression analysis showed that not achieving TO (HR: 4.20; 95% CI: 1.11-15.94; P=0.03) was an independent prognostic factor of poor overall survival. Conclusions:Patients undergoing liver resection for IPNB were more likely to achieve a TO outcome than those requiring a pancreatic resection. Comorbidity, tumor location, and tumor multiplicity influenced overall survival. TO was an independent prognostic factor of overall survival.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- bile duct neoplasms; intraductal precursor lesion; pancreas; surgical resection; textbook outcome
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- ref (ämneskategori)
- art (ämneskategori)
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Lluis, Nuria
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Serradilla-Marti ...
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Achalandabaso, M ...
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Jehaes, Francois
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Dasari, Bobby V. ...
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Mambrilla-Herrer ...
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visa fler...
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Sparrelid, Ernes ...
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Balakrishnan, An ...
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Hoogwater, Frede ...
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Amaral, Maria J.
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Andersson, Bodil
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Berrevoet, Frede ...
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Doussot, Alexand ...
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Lopez-Lopez, Vic ...
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Alsammani, Moham ...
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Detry, Olivier
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Domingo-del Pozo ...
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Machairas, Nikol ...
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Pekli, Damjan
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Alcazar-Lopez, C ...
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Asbun, Horacio
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Björnsson, Bergt ...
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Christophides, T ...
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Diez-Caballero, ...
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Francart, David
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Noel, Colin B.
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Sousa-Silva, Don ...
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Toledo-Martinez, ...
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Tzimas, George N ...
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Yaqub, Sheraz
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Cauchy, Francois
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Prieto-Calvo, Mi ...
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DSouza, Melroy A ...
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Spiers, Harry V. ...
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van den Heuvel, ...
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Charco, Ramon
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Lesurtel, Mickae ...
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Ramia, Jose M.
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