| 1. |
- Elia, Davide, et al.
(författare)
-
The Hi-GAL compact source catalogue - II. The 360° catalogue of clump physical properties
- 2021
-
Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 504:2, s. 2742-2766
-
Tidskriftsartikel (refereegranskat)abstract
- We present the 360° catalogue of physical properties of Hi-GAL compact sources, detected between 70 and 500 $\mu$m. This release not only completes the analogous catalogue previously produced by the Hi-GAL collaboration for -71° 2 á 2 67°, but also meaningfully improves it because of a new set of heliocentric distances, 120 808 in total. About a third of the 150 223 entries are located in the newly added portion of the Galactic plane. A first classification based on detection at 70 $\mu$m as a signature of ongoing star-forming activity distinguishes between protostellar sources (23 per cent of the total) and starless sources, with the latter further classified as gravitationally bound (pre-stellar) or unbound. The integral of the spectral energy distribution, including ancillary photometry from λ = 21 to 1100 $\mu$m, gives the source luminosity and other bolometric quantities, while a modified blackbody fitted to data for $\lambda \ge 160∼\mu$m yields mass and temperature. All tabulated clump properties are then derived using photometry and heliocentric distance, where possible. Statistics of these quantities are discussed with respect to both source Galactic location and evolutionary stage. No strong differences in the distributions of evolutionary indicators are found between the inner and outer Galaxy. However, masses and densities in the inner Galaxy are on average significantly larger, resulting in a higher number of clumps that are candidates to host massive star formation. Median behaviour of distance-independent parameters tracing source evolutionary status is examined as a function of the Galactocentric radius, showing no clear evidence of correlation with spiral arm positions.
|
|
| 2. |
- Dominguez-Rodrigo, M., et al.
(författare)
-
Earliest Acheulian paleolandscape reveals a 1.7 million-year-old megasite at Olduvai Gorge (Tanzania)
- 2023
-
Ingår i: Quaternary Science Reviews. - 0277-3791 .- 1873-457X. ; 316
-
Tidskriftsartikel (refereegranskat)abstract
- FLK West (Bed II, Olduvai Gorge) contains the oldest association of Acheulian stone tools and exploitation of fauna (including megafauna) by hominins in the Pleistocene. Recently, the FLK West paleolandscape has been intensively studied, unveiling a spatial association between archaeological materials and hydrothermal resources. A new type of landscape use by hominins has also been documented around the area where the penecontemporaneous FLK West and HWK site complex were formed, resulting in an array of habitats spanning thousands of square meters covered with large amounts of lithic artefacts. Here, we show how the intensive use of certain environments by hominins resulted in these megasites, in which hominins engaged in a variety of activities, complementary to those performed at discrete archaeological clusters like FLK West. Despite using these habitats redundantly as quarries, hominins performed extensive core reduction of several types of raw materials indicating a dexterity and careful planning undocumented in earlier periods. Here, we also show how palaeoecological reconstructions must be based on fine-scale geological analyses, given the palimpsestic nature of both geological and anthropogenic processes. The research reported here also uncovered an additional unknown source of metamorphic rocks for hominins at Olduvai, which questions a large part of previous modeling based on hominin provisioning exclusively at Naibor Soit. We also show that the manufacture of handaxes was slightly older than documented at FLK West and that they occur in isolation on the landscape in addition to being clustered at sites. This implies that at the beginning of the Acheulian, hominins were not only using and discarding handaxes at specific loci, but they also transported these tools for various activities across the landscape as part of their strategized adaptation to those environments. The occurrence of these intensively-used megasites hints at some territorial behaviors by early Acheulian hominins.
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
|
|
| 6. |
- Wang, T, et al.
(författare)
-
Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders
- 2020
-
Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 11:1, s. 4932-
-
Tidskriftsartikel (refereegranskat)abstract
- Most genes associated with neurodevelopmental disorders (NDDs) were identified with an excess of de novo mutations (DNMs) but the significance in case–control mutation burden analysis is unestablished. Here, we sequence 63 genes in 16,294 NDD cases and an additional 62 genes in 6,211 NDD cases. By combining these with published data, we assess a total of 125 genes in over 16,000 NDD cases and compare the mutation burden to nonpsychiatric controls from ExAC. We identify 48 genes (25 newly reported) showing significant burden of ultra-rare (MAF < 0.01%) gene-disruptive mutations (FDR 5%), six of which reach family-wise error rate (FWER) significance (p < 1.25E−06). Among these 125 targeted genes, we also reevaluate DNM excess in 17,426 NDD trios with 6,499 new autism trios. We identify 90 genes enriched for DNMs (FDR 5%; e.g., GABRG2 and UIMC1); of which, 61 reach FWER significance (p < 3.64E−07; e.g., CASZ1). In addition to doubling the number of patients for many NDD risk genes, we present phenotype–genotype correlations for seven risk genes (CTCF, HNRNPU, KCNQ3, ZBTB18, TCF12, SPEN, and LEO1) based on this large-scale targeted sequencing effort.
|
|
| 7. |
- Acuña, G. J., et al.
(författare)
-
Teaching about complementarity - proposal of classes for university students - including exercises
- 2022
-
Ingår i: Complementarity of Variable Renewable Energy Sources. - : Elsevier. - 9780323855273 - 9780323855280 ; , s. 687-713
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The idea behind this chapter is to provide teachers and students with material that can be used while studying renewable energy sources with special attention paid to their complementary characteristics. The questions and exercises included below refer to chapters presented in the book. In case of any questions, we provide the readers with contact details to chapters corresponding authors who would be happy in assisting you in case of any queries.
|
|
| 8. |
- Barone, Giovanni D., et al.
(författare)
-
Recent developments in the production and utilization of photosynthetic microorganisms for food applications
- 2023
-
Ingår i: Heliyon. - : Elsevier. - 2405-8440. ; 9:4
-
Forskningsöversikt (refereegranskat)abstract
- The growing use of photosynthetic microorganisms for food and food-related applications is driving related biotechnology research forward. Increasing consumer acceptance, high sustain-ability, demand of eco-friendly sources for food, and considerable global economic concern are among the main factors to enhance the focus on the novel foods. In the cases of not toxic strains, photosynthetic microorganisms not only provide a source of sustainable nutrients but are also potentially healthy. Several published studies showed that microalgae are sources of accessible protein and fatty acids. More than 400 manuscripts were published per year in the last 4 years. Furthermore, industrial approaches utilizing these microorganisms are resulting in new jobs and services. This is in line with the global strategy for bioeconomy that aims to support sustainable development of bio-based sectors. Despite the recognized potential of the microalgal biomass value chain, significant knowledge gaps still exist especially regarding their optimized production and utilization. This review highlights the potential of microalgae and cyanobacteria for food and food-related applications as well as their market size. The chosen topics also include advanced production as mixed microbial communities, production of high-value biomolecules, photopro-duction of terpenoid flavoring compounds, their utilization for sustainable agriculture, applica-tion as source of nutrients in space, and a comparison with heterotrophic microorganisms like yeast to better evaluate their advantages over existing nutrient sources. This comprehensive assessment should stimulate further interest in this highly relevant research topic.
|
|
| 9. |
- Elia, Antonis, Dr, et al.
(författare)
-
Cerebral, cardiac and skeletal muscle stress associated with a series of static and dynamic apnoeas
- 2022
-
Ingår i: Scandinavian Journal of Medicine and Science in Sports. - : Wiley. - 0905-7188 .- 1600-0838. ; 32:1, s. 233-241
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose: This study sought to explore, for the first time, the effects of repeated maximal static and dynamic apnoeic attempts on the physiological milieu by assessing cerebral, cardiac and striatal muscle stress-related biomarkers in a group of elite breath-hold divers (EBHD). Methods: Sixteen healthy males were recruited (EBHD = 8; controls = 8). On two separate occasions, EBHD performed two sets of five repeated maximal static apnoeas (STA) or five repeated maximal dynamic apnoeas (DYN). Controls performed a static eupnoeic protocol to negate any effects of water immersion and diurnal variation on haematology (CTL). Venous blood samples were drawn at 30, 90, and 180 min after each protocol to determine S100β, neuron-specific enolase (NSE), myoglobin, and high sensitivity cardiac troponin T (hscTNT) concentrations. Results: S100β and myoglobin concentrations were elevated following both apnoeic interventions (p < 0.001; p ≤ 0.028, respectively) but not after CTL (p ≥ 0.348). S100β increased from baseline (0.024 ± 0.005 µg/L) at 30 (STA, +149%, p < 0.001; DYN, +166%, p < 0.001) and 90 min (STA, +129%, p < 0.001; DYN, +132%, p = 0.008) following the last apnoeic repetition. Myoglobin was higher than baseline (22.3 ± 2.7 ng/ml) at 30 (+42%, p = 0.04), 90 (+64%, p < 0.001) and 180 min (+49%, p = 0.013) post-STA and at 90 min (+63%, p = 0.016) post-DYN. Post-apnoeic S100β and myoglobin concentrations were higher than CTL (STA, p < 0.001; DYN, p ≤ 0.004). NSE and hscTNT did not change from basal concentrations after the apnoeic (p ≥ 0.146) nor following the eupnoeic (p ≥ 0.553) intervention. Conclusions: This study suggests that a series of repeated maximal static and dynamic apnoeas transiently disrupt the blood-brain barrier and instigate muscle injury but do not induce neuronal-parenchymal damage or myocardial damage.
|
|
| 10. |
- Elkadeem, M. R., et al.
(författare)
-
Geospatial-assisted multi-criterion analysis of solar and wind power geographical-technical-economic potential assessment
- 2022
-
Ingår i: Applied Energy. - : Elsevier Ltd. - 0306-2619 .- 1872-9118. ; 322
-
Tidskriftsartikel (refereegranskat)abstract
- Amid the increasing electricity demand, energy crisis and pollution, the transition to renewable energy (RE) is becoming a preoccupation and major global challenge due to the multidimensional and intricate problem of RE planning. In Egypt, about 90% of gross power generation comes from carbon-intensive power plants (natural gas and coal). Here, we propose a novel geospatial-decision-making model aimed at geographical-technical–economic potential mapping and assessment of solar photovoltaic (PV) and onshore wind turbine (WT) power plants at a high level of resolution (1 km2) in Egypt. We identify the locations suitable for PV and WT development considering sixteen restrictive and contradictory evaluation criteria. These locations have been further analyzed to estimate how much energy generation is available and at what energy cost. The analysis identifies Middle-Upper Egypt and Suez Canal as hosting the majority of highly suitable locations for PV and WT power plants, respectively. Our finding reveals that the proper planning on RE projects at the proposed optimum locations could support the country's energy mix with a sizable 32% share of the projected country's electricity consumption from PV and 50% share from WT, by 2030. Furthermore, we show that the investment opportunities of PV and WT generation are potentially attractive with affordable competitive prices estimated at 57.84 $/MWh and 32.36 $/MWh, respectively, against conventional generation for today and the future. We anticipate that our results will provide valuable support in realizing Egypt's vision for sustainable electricity generation and in keeping abreast of the global transformation in power systems being witnessed. Ultimately, the method's relevance extends beyond the geographical boundaries of the present territory; it features a strategic, clear and reproducible approach that may be applied to a larger area or continent, provided the necessary input data and criteria are introduced.
|
|
