| 1. |
- Eriksson, Siw, 1962, et al.
(författare)
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‘Co-Creation’ is On Everyone’s Lips – Designers’ Perception of Opportunities For and Barriers To Co-Creation in Product Development Organizations
- 2022
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Co-creation, aimed at encouraging users to become active partners throughout the development process, has been widely discussed in academia for the last 10-15 years as a strategy for sustainable design of products that fulfil users’ needs and enhance users’ experience of future products. However, despite the fact that universities have undertaken to educate future designers on methods and tools for co-creation with users, we emphasize that there is still a noticeable gap between theory and practice, as designers’ opportunities for incorporating co-creation activities in product development organizations remain limited. The aim of this study, consisting of twelve semi-structured, in-depth interviews with design practitioners from Swedish industry, was to create a deeper understanding of the extent to which designers can and do actively involve users in the design process in industrial organizations. While we found that designers were interested and willing to work in a more user-centered way, there was no evidence of co-creation with users. The companies’ marketing departments were mainly responsible for customer/user contact, identifying and communicating user/customer requirements by means of traditional marketing methods. Hence direct communication between designers and users was rarely supported. Moreover, the informants often experienced a strong reluctance from the marketing department to provide them with necessary contacts, as this might interfere with their relationship with the customer. The barriers to accessing users were even more pronounced for designers in consultancy firms, where the customer functioned as the link to the market and frequently declined to allocate resources to user studies, arguing that they already possessed the necessary knowledge or that such studies were too costly. Consequently, irrespective of intra- or inter-organizational settings, designers’ ability to access users often depended on individual motivation and initiatives rather than organizational factors.
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| 2. |
- Eriksson, Siw, 1962, et al.
(författare)
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Genuine co-design : an activity theory analysis involving emergency nurses in an interdisciplinary new product development project of a novel medical device
- 2021
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Ingår i: International Journal of Human Factors and Ergonomics. - 2045-7804 .- 2045-7812. ; 8:4, s. 331-369
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Tidskriftsartikel (refereegranskat)abstract
- This study analysed a series of workshops and explored prerequisites for interdisciplinary co-design among industrial designers, design engineers and users in the development of a novel medical device. Presented as a case study, this paper focus on what affects participants’ transformative processes towards genuine participation in co-design processes. Based on activity theory, we suggest that co-design activities have to support not only users, but all participants, shifting their perspectives beyond their own domain’s rules, motives, objects and division of labour, i.e., beyond their own activity system, to support users’ participation as equal members in design teams. We propose that genuine co-design requires a holistic approach where a neutral arena, an impartial facilitator, clear rules of play, along with representational artefacts as mediating tools in the formation of a new collective activity system to foster equality, mutual value and long-term knowledge generation. Such approach requires a process over time.
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| 3. |
- Molin, Mikael, 1973, et al.
(författare)
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Protein kinase A controls yeast growth in visible light
- 2020
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Ingår i: BMC Biology. - : Springer Science and Business Media LLC. - 1741-7007. ; 18:1
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Tidskriftsartikel (refereegranskat)abstract
- Background: A wide variety of photosynthetic and non-photosynthetic species sense and respond to light, having developed protective mechanisms to adapt to damaging effects on DNA and proteins. While the biology of UV light-induced damage has been well studied, cellular responses to stress from visible light (400–700 nm) remain poorly understood despite being a regular part of the life cycle of many organisms. Here, we developed a high-throughput method for measuring growth under visible light stress and used it to screen for light sensitivity in the yeast gene deletion collection. Results: We found genes involved in HOG pathway signaling, RNA polymerase II transcription, translation, diphthamide modifications of the translational elongation factor eEF2, and the oxidative stress response to be required for light resistance. Reduced nuclear localization of the transcription factor Msn2 and lower glycogen accumulation indicated higher protein kinase A (cAMP-dependent protein kinase, PKA) activity in many light-sensitive gene deletion strains. We therefore used an ectopic fluorescent PKA reporter and mutants with constitutively altered PKA activity to show that repression of PKA is essential for resistance to visible light. Conclusion: We conclude that yeast photobiology is multifaceted and that protein kinase A plays a key role in the ability of cells to grow upon visible light exposure. We propose that visible light impacts on the biology and evolution of many non-photosynthetic organisms and have practical implications for how organisms are studied in the laboratory, with or without illumination.
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| 4. |
- Nunez, J. C. B., et al.
(författare)
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Footprints of natural selection at the mannose-6-phosphate isomerase locus in barnacles
- 2020
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424. ; 117:10, s. 5376-5385
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Tidskriftsartikel (refereegranskat)abstract
- The mannose-6-phosphate isomerase (Mpi) locus in Semibalanus balanoides has been studied as a candidate gene for balancing selection for more than two decades. Previous work has shown that Mpi allozyme genotypes (fast and slow) have different fre-quencies across Atlantic intertidal zones due to selection on post-settlement survival (i.e., allele zonation). We present the complete gene sequence of the Mpi locus and quantify nucleotide polymor-phism in S. balanoides, as well as divergence to its sister taxon Semibalanus cariosus. We show that the slow allozyme contains a derived charge-altering amino acid polymorphism, and both allo-zyme classes correspond to two haplogroups with multiple internal haplotypes. The locus shows several footprints of balancing selec-tion around the fast/slow site: an enrichment of positive Tajima's D for nonsynonymous mutations, an excess of polymorphism, and a spike in the levels of silent polymorphism relative to silent diver-gence, as well as a site frequency spectrum enriched for midfre-quency mutations. We observe other departures from neutrality across the locus in both coding and noncoding regions. These in-clude a nonsynonymous trans-species polymorphism and a recent mutation under selection within the fast haplogroup. The latter suggests ongoing allelic replacement of functionally relevant amino acid variants. Moreover, predicted models of Mpi protein structure provide insight into the functional significance of the putatively selected amino acid polymorphisms. While footprints of selection are widespread across the range of S. balanoides, our data show that intertidal zonation patterns are variable across both spatial and temporal scales. These data provide further evidence for heteroge-neous selection on Mpi.
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